AET, Dihydrobromide 2-Aminoethylisothiouronium Bromide 15435 Calbiochem-Novabiochem Corp. 10394 Pacific Center Court San Diego, CA 92121 (858)450-5558/(800)854-3417 FAX: (858)453-3552 Material Safety Data Sheet Common Name Supplier Synonym In Case of Emergency Section 1. Chemical Product and Company Identification Catalog # Call ChemtrecŪ (800)424-9300 (within U.S.A.) (703)527-3887 (outside U.S.A.) Order Number Customer Number 1) AET, Dihydrobromide 56-10-0 Not available. Section 2. Composition, Information on Ingredients Name CAS # Exposure Limits CARCINOGENIC EFFECTS : Classified None. by NIOSH. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion. Emergency Overview Medical Conditions Aggravated by Overexposure: Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. Not available. Overexposure /Signs/Symptoms Section 3. Hazards Identification Routes of Entry Potential Acute Health Effects Potential Chronic Health Effects Very hazardous in case of inhalation. May be fatal if inhaled. Hazardous in case of eye contact (irritant). Very hazardous in case of ingestion. May be fatal if swallowed. Very hazardous in case of skin contact (permeator). Hazardous in case of skin contact (irritant). Severe over-exposure can result in death. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering. Eyes Skin Inhalation Ingestion Physical State and Appearance Solid. (Solid powder.) See Toxicological Information (section 11) WARNING! HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED. MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION. Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing dust. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. Page: 1/5 Catalog # 15435 If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. Section 4. First Aid Measures Eye Contact Skin Contact Inhalation Ingestion Not available. Notes to Physician May be combustible at high temperature. These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...), halogenated compounds. Not available. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Not available. Not available. Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. Not available. Section 5. Fire Fighting Measures Flammability of the Product Flash Points Products of Combustion Fire Hazards in Presence of Various Substances Explosion Hazards in Presence of Various Substances Fire Fighting Media and Instructions Special Remarks on Fire Hazards Special Remarks on Explosion Hazards Be sure to use an approved/certified respirator or equivalent. Protective Clothing (Fire) Use appropriate tools to put the spilled solid in a convenient waste disposal container. Poisonous solid. Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Call for assistance on disposal. Section 6. Accidental Release Measures Small Spill and Leak Large Spill and Leak Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20°C (-4°F). Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing dust. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. Section 7. Handling and Storage Handling Storage Page: 2/5 Catalog # 15435 Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. 1) AET, Dihydrobromide Not available. Section 8. Exposure Controls, Personal Protection Engineering Controls Personal Protection in Case of a Large Spill Product Name Exposure Limits Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Splash goggles. Lab coat. Gloves. Not applicable. Personal Protection Eyes Body Respiratory Hands Feet Protective Clothing (Pictograms) Consult local authorities for acceptable exposure limits. Not available. Solid. (Solid powder.) 189 to 193°C (372.2 to 379.4°F) Not available. Not available. Not applicable. Easily soluble in cold water. 281 g/mole White. Boiling/Condensation Point Melting/Freezing Point Section 9. Physical and Chemical Properties Physical State and Appearance Molecular Weight Specific Gravity Vapor Pressure Vapor Density Solubility Color C3H9N3S . 2HBr Molecular Formula The product is stable. Reactive with oxidizing agents. Not available. These products are halogenated compounds. Section 10. Stability and Reactivity Stability and Reactivity Incompatibility with Various Substances Hazardous Decomposition Products Hazardous Polymerization Page: 3/5 Catalog # 15435 Acute oral toxicity (LD50): 177 mg/kg [Dog]. Very hazardous in case of skin contact (permeator), of ingestion, . Hazardous in case of skin contact (irritant), of inhalation (lung irritant). CARCINOGENIC EFFECTS : Classified None. by NIOSH. Toxic for humans or animal life. Material is irritating to mucous membranes and upper respiratory tract. Not available. Section 11. Toxicological Information Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Special Remarks on Toxicity to Animals Special Remarks on Chronic Effects on Humans Special Remarks on Other Toxic Effects on Humans RTECS # UM0175000 Not available. The products of degradation are less toxic than the product itself. Section 12. Ecological Information Ecotoxicity Toxicity of the Products of Biodegradation Waste must be disposed of in accordance with federal, state and local environmental control regulations. Not available. Waste Information Waste Stream Section 13. Disposal Considerations Consult your local or regional authorities. Toxic solid, organic, n.o.s.* Not available. CLASS 6.1: Toxic substance. CLASS 6.1: Toxic substance. Marine Pollutant Not available. CLASS 6.1: Toxic substance. Section 14. Transport Information DOT Classification Special Provisions for Transport TDG Classification IMO/IMDG Classification ICAO/IATA Classification ADR/RID Classification Toxic solid, organic, n.o.s.*, 6.1, UN2811, II CLASS 6.1: Poisonous material. CLASS: 9.2: Environmentally hazardous material. Toxic solid, organic, n.o.s.*, 6.1, 9.2, UN2811, II Page: 4/5 Catalog # 15435 U.S. Federal Regulations No products were found. CLASS: Toxic. CLASS: Irritating substance. HCS Classification Section 15. Regulatory Information California prop. 65: No products were found. TSCA 8(b) inventory: AET, Dihydrobromide Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean air act (CAA) 112 accidental release prevention: No products were found. Clean air act (CAA) 112 regulated flammable substances: No products were found. Clean air act (CAA) 112 regulated toxic substances: No products were found. State Regulations CEPA NDSL: AET, Dihydrobromide Philippines (RA6969): AET, Dihydrobromide WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC). R23/24/25- Toxic by inhalation, in contact with skin and if swallowed. R36/37/38- Irritating to eyes, respiratory system and skin. DSCL (EEC) International Regulations Not available. EINECS International Lists SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. SARA 313 toxic chemical notification and release reporting: No products were found. Section 16. Other Information Notice to Reader To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Hazardous Material Information System (U.S.A.) 3 1 0 E 0 1 3 National Fire Protection Association (U.S.A.) Health Specific Hazard Reactivity Fire Hazard Health Fire Hazard Reactivity Personal Protection HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED. MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION. Label Requirements Page: 5/5 7/9/2002. Date of issue Catalog # 15435