Material Safety Data Sheet **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION **** MSDS Name: 4-Ethoxymethylene-2-Phenyl-2-Oxazolin- 5-One, 97% Catalog Numbers: AC227980000, AC227980050, AC227980100 Synonyms: Company Identification (Europe): Acros Organics BVBA Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Company Identification (USA): Acros Organics One Reagent Lane Fairlawn, NJ 07410 For information in North America, call: 800-ACROS-01 For information in Europe, call: 0032(0) 14575211 For emergencies in the US, call CHEMTREC: 800-424-9300 For emergencies in Europe, call: 0032(0) 14575299 **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 15646-46-5 |4 Ethoxymethylene-2-Phenyl-2-Oxazolin-| 97 | 239-713-9 | | |5-One | | | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: None Listed. Risk Phrases: None Listed. **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. The toxicological properties of this material have not been fully investigated. Skin: May cause skin irritation. The toxicological properties of this material have not been fully investigated. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation. **** SECTION 7 - HANDLING and STORAGE **** Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES **** Physical State: Powder Appearance: white to off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 93.00 - 94.00 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility: Specific Gravity/Density: Molecular Formula: C12H11NO3 Molecular Weight: 217.22 **** SECTION 10 - STABILITY AND REACTIVITY **** Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Not available. **** SECTION 11 - TOXICOLOGICAL INFORMATION **** RTECS#: CAS# 15646-46-5: RQ5786250 LD50/LC50: Not available. Carcinogenicity: 4 Ethoxymethylene-2-Phenyl-2-Oxazolin-5-One - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available. Mutagenicity: No information available. Other Studies: No data available. **** SECTION 12 - ECOLOGICAL INFORMATION **** **** SECTION 13 - DISPOSAL CONSIDERATIONS **** Dispose of in a manner consistent with federal, state, and local regulations. **** SECTION 14 - TRANSPORT INFORMATION **** US DOT No information available Canadian TDG No information available. **** SECTION 15 - REGULATORY INFORMATION **** US FEDERAL TSCA CAS# 15646-46-5 is not listed on the TSCA inventory. It is for research and development use only. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE 4 Ethoxymethylene-2-Phenyl-2-Oxazolin-5-One is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 15646-46-5: No information available. United Kingdom Occupational Exposure Limits Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 15646-46-5 is not listed on Canada's Ingredient Disclosure List. Exposure Limits **** SECTION 16 - ADDITIONAL INFORMATION **** MSDS Creation Date: 4/27/1998 Revision #1 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------