SIGMA CHEMICAL CO -- 5-HYDROXYTRYPTAMINE HYDROCHLORIDE, H5755 ======================================================= MSDS Safety Information ======================================================= FSC: 6810 MSDS Date: 11/19/1991 MSDS Num: BMNYX LIIN: 00N024924 Product ID: 5-HYDROXYTRYPTAMINE HYDROCHLORIDE, H5755 MFN: 01 Responsible Party Cage: 21076 Name: SIGMA CHEMICAL CO Box: 14508 City: ST. LOUIS MO 63178 Info Phone Number: 800-325-3010; 314-771-5750 Emergency Phone Number: 314-771-5765 Published: Y ======================================================= Contractor Summary ======================================================= Cage: 21076 Name: SIGMA CHEMICAL COMPANY Address: 3050 SPRUCE ST Box: 14508 City: ST LOUIS MO 63178 Phone: 314-771-5765 ======================================================= Ingredients ======================================================= Name: 5-HYDROXYTRYPTAMINE HYDROCHLORIDE ======================================================= Health Hazards Data ======================================================= LD50 LC50 Mixture: NONE SPECIFIED BY MANUFACTURER. Route Of Entry Inds - Inhalation: YES Skin: YES Ingestion: YES Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO Effects of Exposure: ACUTE: HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION. CHRONIC: OVEREXP MAY CAUSE REPRODUCTIVE DISORDER(S) BASED ON TESTS WITH LABORATORY ANIMALS. TARGET ORGANS: NERVES, SMOOTH MUSCLE, VASCULAR SYSTEM, ENDOCRINE SYSTEM. POSSIBLE TERATOGEN. HYGROSCOPIC. (EFTS OF OVEREXP) Explanation Of Carcinogenicity: NOT RELEVANT Signs And Symptions Of Overexposure: HLTH HAZ: POSSIBLE RISK OF IRREVERSIBLE EFFECTS. Medical Cond Aggravated By Exposure: NONE SPECIFIED BY MANUFACTURER. First Aid: EYES: IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SKIN: IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER. INHAL: REMOVE TO FRESH AIR. IF NOT BREATHING GIV E ARTF RESP. IF BREATHING IS DIFFICULT,GIVE O2. INGEST: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL MD. ======================================================= Handling and Disposal ======================================================= Spill Release Procedures: WEAR NIOSH/MSHA APPROVED RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN BAG & HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENT AREA & WASH SPILL SITE AF TER MATL PICKUP IS COMPLETE. Neutralizing Agent: NONE SPECIFIED BY MANUFACTURER. Waste Disposal Methods: DISSOLVE OR MIX THE MATL W/COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN AFTER BURNER & SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS. Handling And Storage Precautions: STORE IN COOL DRY PLACE. AVOID BREATHING DUST. AVOID CONTACT WITH EYES, SKIN AND CLOTHING. KEEP CONTAINER CLOSED. LIGHT SENSITIVE. Other Precautions: HARMFUL BY INHALATION, CONTACT WITH SKIN AND INGEST. POSSIBLE RISK OF IRRIVERSIBLE EFTS. WEAR SUITABLE PROTECTIVE CLOTHING. ======================================================= Fire and Explosion Hazard Information ======================================================= Extinguishing Media: WATER SPRAY, CO2, DRY CHEMICAL POWDER OR APPROPRIATE FOAM. Fire Fighting Procedures: WEAR NIOSH/MSHA APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT (FP N). Unusual Fire/Explosion Hazard: EMITS TOXIC FUMES UNDER FIRE CONDITIONS. ======================================================= Control Measures ======================================================= Respiratory Protection: WEAR NIOSH/MSHA APPROVED RESPIRATOR APPROPRIATE FOR EXPOSURE OF CONCERN (FP N). Ventilation: MECHANICAL EXHAUST REQUIRED. Protective Gloves: IMPERVIOUS GLOVES (FP N). Eye Protection: CHEMICAL WORKERS GOGGLES (FP N). Other Protective Equipment: WEAR SUITABLE PROTECTIVE CLOTHING. Work Hygienic Practices: WASH THOROUGHLY AFTER HANDLING. Supplemental Safety and Health: NONE SPECIFIED BY MANUFACTURER. ======================================================= Physical/Chemical Properties ======================================================= HCC: N1 M.P/F.P Text: 297F,147C Appearance and Odor: OFF-WHITE POWDER. ======================================================= Reactivity Data ======================================================= Stability Indicator: YES Stability Condition To Avoid: MAY DISCOLOR ON EXPOSURE TO LIGHT. Materials To Avoid: STRONG OXIDIZING AGENTS. Hazardous Decomposition Products: TOXIC FUMES OF CO, CO2, NOX, HYDROGEN CHLORIDE GAS. Hazardous Polymerization Indicator: NO Conditions To Avoid Polymerization: NOT RELEVANT ======================================================= Toxicological Information ======================================================= ======================================================= Ecological Information ======================================================= ======================================================= MSDS Transport Information ======================================================= ======================================================= Regulatory Information ======================================================= ======================================================= Other Information ======================================================= ======================================================= Transportation Information ======================================================= Responsible Party Cage: 21076 Trans ID NO: 29587 Product ID: 5-HYDROXYTRYPTAMINE HYDROCHLORIDE, H5755 MSDS Prepared Date: 11/19/1991 Review Date: 04/30/1992 MFN: 1 AF MMAC Code: Z Multiple KIT Number: 0 Review IND: Y ======================================================= Detail DOT Information ======================================================= DOT PSN Code: ZZZ DOT Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION ======================================================= Detail IMO Information ======================================================= IMO PSN Code: ZZZ IMO Proper Shipping Name: NOT REGULATED FOR THIS MODE OF TRANSPORTATION ======================================================= Detail IATA Information ======================================================= IATA PSN Code: ZZZ IATA Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION ======================================================= Detail AFI Information ======================================================= AFI PSN Code: ZZZ AFI Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION ======================================================= HAZCOM Label ======================================================= Product ID: 5-HYDROXYTRYPTAMINE HYDROCHLORIDE, H5755 Cage: 21076 Company Name: SIGMA CHEMICAL COMPANY Street: 3050 SPRUCE ST PO Box: 14508 City: ST LOUIS MO Zipcode: 63178 Health Emergency Phone: 314-771-5765 Label Required IND: Y Date Of Label Review: 01/20/1992 Status Code: C Label Date: 01/20/1992 Origination Code: G Chronic Hazard IND: Y Eye Protection IND: YES Skin Protection IND: YES Signal Word: WARNING Respiratory Protection IND: YES Health Hazard: Moderate Contact Hazard: Slight Fire Hazard: None Reactivity Hazard: None Hazard And Precautions: ACUTE: HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION. AVOID BREATHING DUST. AVOID CONTACT W/EYES, SKIN AND CLOTHING. KEEP CONTAINER CLOSED WHEN NOT IN USE. CHRONIC: MAY CAUSE REPRODUCTIVE DISORDERS. POSSIBLE TERATOGEN. ======================================================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever expressly or implied warrants, states, or intends said information to have any application, use or viability by or to any person or persons outside the Department of Defense nor any person or persons contracting with any instrumentality of the United States of America and disclaims all liability for such use. Any person utilizing this instruction who is not a military or civilian employee of the United States of America should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation regardless of similarity to a corresponding Department of Defense or other government situation.