Material Safety Data Sheet Acetone-d6, 100.0 atom % D ACC# 95391 Section 1 - Chemical Product and Company Identification MSDS Name: Acetone-d6, 100.0 atom % D Catalog Numbers: AC174820000, AC174820010, AC174820050, AC174820250 Synonyms: 2-Propanone Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410 For information in North America, call: 800-ACROS-01 For emergencies in the US, call CHEMTREC: 800-424-9300 Section 2 - Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS 666-52-4 Acetone-d6 211-563-9 Section 3 - Hazards Identification EMERGENCY OVERVIEW Appearance: colorless clear liquid. Flash Point: -20 deg C. Hygroscopic (absorbs moisture from the air). Target Organs: Kidneys, central nervous system, liver, respiratory system, skin. Potential Health Effects Eye: Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. Skin: Exposure may cause irritation characterized by redness, dryness, and inflammation. Ingestion: May cause irritation of the digestive tract. May cause central nervous system depression, kidney damage, and liver damage. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause motor incoordination and speech abnormalities. May cause narcotic effects in high concentration. Chronic: Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation may cause effects similar to those of acute inhalation. Section 4 - First Aid Measures Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Wash mouth out with water. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - Fire Fighting Measures General Information: If breathing is difficult, give oxygen. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Vapor may cause flash fire. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Flash Point: -20 deg C ( -4.00 deg F) Autoignition Temperature: Not available. Explosion Limits, Lower:2.50 vol % Upper: 13.00 vol % NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0 Section 6 - Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wear appropriate protective clothing to minimize contact with skin. Remove all sources of ignition. Section 7 - Handling and Storage Handling: Use with adequate ventilation. Use spark-proof tools and explosion proof equipment. Avoid breathing dust, mist, or vapor. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep away from heat, sparks and flame. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Flammables-area. Store under nitrogen. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs Acetone-d6 none listed none listed none listed OSHA Vacated PELs: Acetone-d6: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Wear appropriate gloves to prevent skin exposure. Clothing: Wear polyethylene gloves, apron, and/or clothing. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - Physical and Chemical Properties Physical State: Clear liquid Appearance: colorless Odor: Not available. pH: Not available. Vapor Pressure: 247 mbar @ 20 deg C Vapor Density: 2.0 Evaporation Rate:7.7 (n-Butyl acetate=1) Viscosity: Not available. Boiling Point: 56 deg C @ 760.00mm Hg Freezing/Melting Point:-94 deg C Decomposition Temperature:Not available. Solubility: Not available. Specific Gravity/Density:.7910g/cm3 Molecular Formula:CD3COCD3 Molecular Weight:64.13 Section 10 - Stability and Reactivity Chemical Stability: Not available. Conditions to Avoid: Incompatible materials, moisture, temperatures above 220°C. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, bases. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - Toxicological Information RTECS#: CAS# 666-52-4 unlisted. LD50/LC50: Not available. Carcinogenicity: CAS# 666-52-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65. Epidemiology: No information available. Teratogenicity: No. 13672] Reproductive Effects: No data available. Mutagenicity: No data available. Neurotoxicity: No information available. Other Studies: Section 12 - Ecological Information Ecotoxicity: No data available. Harlequin fish LC50:5700 ppm/24H Daphnia magna ED50:10 mg/l/24,48H Brine shrimp LD50:2100 mg/l/24,48H at 24øC Environmental: No information available. Physical: No information available. Other: None. Section 13 - Disposal Considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. Section 14 - Transport Information US DOT Canada TDG Shipping Name: ACETONE ACETONE Hazard Class: 3 3 UN Number: UN1090 UN1090 Packing Group: II II Additional Info: FLASHPOINT -17 C Section 15 - Regulatory Information US FEDERAL TSCA CAS# 666-52-4 is not listed on the TSCA inventory. It is for research and development use only. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. CERCLA Hazardous Substances and corresponding RQs None of the chemicals in this material have an RQ. SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ. Section 313 No chemicals are reportable under Section 313. Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE CAS# 666-52-4 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California Prop 65 California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI F Risk Phrases: R 11 Highly flammable. R 36 Irritating to eyes. R 66 Repeated exposure may cause skin dryness or cracking. R 67 Vapours may cause drowsiness and dizziness. Safety Phrases: S 16 Keep away from sources of ignition - No smoking. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 9 Keep container in a well-ventilated place. WGK (Water Danger/Protection) CAS# 666-52-4: No information available. Canada - DSL/NDSL None of the chemicals in this product are listed on the DSL or NDSL list. Canada - WHMIS not available. This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations. Canadian Ingredient Disclosure List Section 16 - Additional Information MSDS Creation Date: 1/15/1998 Revision #12 Date: 9/26/2007 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.