Material Safety Data Sheet **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION **** MSDS Name: Cadmium Chloride Catalog Numbers: C10 100, C10 500, C10-100, C10-500, C10100, C10500, S75062, S75063, S79936, S79938ACS Synonyms: Cadmium Dichloride Company Identification: Fisher Scientific 1 Reagent Lane Fairlawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887 **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 10108-64-2 |Cadmium Chloride | >99% | 233-296-7 | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: T Risk Phrases: 45 48/23/25 **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW May cause cancer. Toxic : danger of serious damage to health by prolonged exposure through inhalation and if swallowed.Hygroscopic. Potential Health Effects Eye: Exposure to the substance as an aqueous solution may cause irritation and corneal abnormalities. Skin: Exposure may cause irritation and possible burns. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Exposure may cause severe swelling of face and neck areas with possible death. Inhalation: May cause respiratory tract irritation. Irritation may lead to chemical pneumonitis and pulmonary edema. May cause ulceration and perforation of the nasal septum if inhaled in excessive quantities. May cause pulmonary fibrosis and permanent damage. Chronic: May cause respiratory tract cancer. Prolonged or repeated exposure may cause permanent bone structure abnormalities. May cause liver and kidney damage. Chronic inhalation may cause nasal septum ulceration and perforation. Chronic inhalation of cadmium compounds has been associated with lung and prostrate cancer. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Antidote: The use of Calcium disodium EDTA as a chelating agent should be determined by qualified medical personnel. **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use extinguishing media appropriate to the surrounding fire. Dusts may be combustible when exposed to heat, flame, or oxidizing agents. Extinguishing Media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. **** SECTION 7 - HANDLING and STORAGE **** Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Storage: Keep away from sources of ignition. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use substance with extreme caution and designate regulated areas for use. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear impervious gloves. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES **** Physical State: Solid Appearance: white Odor: odorless pH: Not available. Vapor Pressure: 10 mm Hg Vapor Density: Not available. Evaporation Rate: Not available. Viscosity: Not available. Boiling Point: 967 deg C @ 760.00mmHg Freezing/Melting Point: 568 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility: 1400 G/L (20&C) Specific Gravity/Density: Molecular Formula: CDCL2 Molecular Weight: 183.32 **** SECTION 10 - STABILITY AND REACTIVITY **** Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, ignition sources, dust generation, excess heat. Incompatibilities with Other Materials: Bromine trifluoride, hydrogen azide, oxidizers, potassium, selenium, tellurium, zinc. Hazardous Decomposition Products: Irritating and toxic fumes and gases, cadmium fumes, chloride fumes. Hazardous Polymerization: Has not been reported. **** SECTION 11 - TOXICOLOGICAL INFORMATION **** RTECS#: CAS# 10108-64-2: EV0175000 LD50/LC50: CAS# 10108-64-2: Oral, mouse: LD50 = 60 mg/kg; Oral, rat: LD50 = 88 mg/kg. Carcinogenicity: Cadmium Chloride - ACGIH: A2 - suspected human carcinogen (elemental) (listed as ** California: carcinogen; initial date 10/1/87 (listed as ** undefined * NIOSH: occupational carcinogen (listed as ** undefined **) NTP: Known carcinogen OSHA: Possible select carcinogen (listed as ** undefined **). IARC: Group 1 carcinogen (listed as ** undefined **). Epidemiology: Studies suggest that occupational inhalation of cadmium is correlated with an increased lung cancer risk. Please refer to Patty's Industrial Hygiene and Toxicology and IARC volume 11 for a more detailed discussion. Teratogenicity: Effects on Newborn: reduced weight gain, orl-mouse TDLo=6 mg/kg; other postnatal effects, orl-rat TDLo=48 mg/kg. Embryo or Fetus: death, orl-rat TDLo=14677 ug/kg and ihl-rat TCLo=130 ug/m3; stunted fetus, orl-rat TDLo=130 mg/kg; maternal-fetal exchange effects, scu-rat TDLo=7 mg/kg. Specific Developmental Abnormalities: cardiovascular, orl-rat TDLo=280 mg/kg; CNS, ipr-rat TDLo=2 mg/kg; craniofacial, ipr-mouse TDLo=1833 ug/kg; musculoskeletal, orl-rat TDLo=17 mg/kg; respiratory, scu-rat TDLo=32 mg/kg. Reproductive Effects: Fertility: litter size and post-implantation mortality, orl-rat TDLo=652 mg/kg. Maternal Effects: ovaries/fallopian tubes, orl-rat TDLo=652 mg/kg. Paternal Effects: spermatogenesis and testes/sperm duct/epididymis, scu-rat TDLo=1250 ug/kg. Neurotoxicity: No information available. Mutagenicity: DNA Damage: hamster embryo 2 umol/L, mammal lymphocyte 350 umol/L. DNA Inhibition: hamster lung and mammal kidney 2 umol/L. Unscheduled DNA Synthesis: hamster embryo 10 umol/L. Gene Mutation in Mammal Cells: hamster lung 1 umol/L. Other Studies: Please refer to RTECS EVO175000 for additional data. **** SECTION 12 - ECOLOGICAL INFORMATION **** Ecotoxicity: Fish: Bluegill/Sunfish: 1.94ppm; 96HJapanese quail, oral LC50=2584 ppm/5D Ring-necked pheasant, oral LC50=767 ppm/5D Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA." **** SECTION 13 - DISPOSAL CONSIDERATIONS **** Dispose of in a manner consistent with federal, state, and local regulations. **** SECTION 14 - TRANSPORT INFORMATION **** US DOT Shipping Name: CADMIUM COMPOUMDS Hazard Class: 6.1 UN Number: UN2570 Packing Group: III Canadian TDG Shipping Name: CADMIUM COMPOUNDS NOS (CADMIUM CHLORIDE) Hazard Class: 6.1(9.2) UN Number: UN2570 **** SECTION 15 - REGULATORY INFORMATION **** US FEDERAL TSCA CAS# 10108-64-2 is listed on the TSCA inventory. This material does not contain any Class 2 Ozone depletors. Clean Water Act: CAS# 10108-64-2 is listed as a Hazardous Substance under the CWA. CAS# 10108-64-2 is listed as a Priority Pollutant under the Clean Water Act. CAS# 10108-64-2 is listed as a Toxic Pollutant under the Clean Water Act. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE Cadmium Chloride can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, (listed as ** no name **), Minnesota, (listed as ** no name **), Massachusetts. The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act: WARNING: This product contains Cadmium Chloride, listed as ` ** undefined **', a chemical known to the state of California to cause cancer. WARNING: This product contains Cadmium Chloride, listed as ` ** undefined **', a chemical known to the state of California to cause birth defects or other reproductive harm. California No Significant Risk Level: CAS# 10108-64-2: inhalation: no significant risk level = 0.05 ug/day (listed under ** no name **) European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 45 May cause cancer. R 48/23/25 Toxic : danger of serious damage to health by prolonged exposure through inhalation and if swallowed. Safety Phrases: S 53 Avoid exposure - obtain special instructions before use. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 10108-64-2: No information available. United Kingdom Occupational Exposure Limits Canada CAS# 10108-64-2 is listed on Canada's DSL List. CAS# 10108-64-2 is listed on Canada's Ingredient Disclosure List. Exposure Limits CAS# 10108-64-2: OEL-ARAB Republic of Egypt:TWA 0.05 mg(Cd)/m3 OEL-AUSTRALIA:TWA 0.05 mg(Cd)/m3 OEL-BELGIUM:TWA 0.05 mg(Cd)/m3 OEL-CZECHOSLOVAKIA:TWA 0.05 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 OEL-DENMARK:TWA 0.01 mg(Cd)/m3 OEL-FINLAND:TWA 0.02 mg(Cd)/m3;Carcinogen OEL-FRANCE;Skin OEL-GERMANY;Carcinogen OEL-INDIA:TWA 0.05 mg(Cd)/m3 OEL-JAPAN:TWA 0.05 mg(Cd)/m3 OEL-THE NETHERLANDS:TWA 0.02 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 OEL-THE PHILIPPINES:TWA 0.2 mg(Cd)/m3 OEL-RUSSIA:TWA 0.01 mg(Cd)/m3;STEL 0.05 mg(Cd)/m3 OEL-SWEDEN:TWA 0.02 mg(Cd)/m3;Carcinogen OEL-SWITZERLAND:TWA 0.05 mg(Cd)/m3 OEL-SWITZERLAND;Carcinogen OEL-THAILAND:TWA 0.2 mg(Cd)/m3;STEL 0.5 mg(Cd)/m3 OEL-TURKEY:TWA 0.2 mg(Cd)/m3 OEL-UNITED KINGDOM:TWA 0.01 mg(Cd)/m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV **** SECTION 16 - ADDITIONAL INFORMATION **** MSDS Creation Date: 6/08/1999 Revision #1 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------