In USA: In Europe:
Pierce Perbio Science
P.O. Box 117 Industriezone III
Rockford, IL 61105 Industrielaan 27
USA 9320 Erembodegem-Aalst
815.968.0747 or Belgium
1.800.874.3723 Tel:+32 53 83 44 04
Fax:+32 53 83 76 38
Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
CarboLink Coupling Gel
1106
1852700 1886250 20391 20392 20392B
5/16/2006
5/16/2006
Product Name
Supplier Manufacturer
Product no.
MSDS#
Validation date
Print date In case of emergency
Section 1. Chemical Product and Company Identification
Responsible Name MSDS Administrator
Use of the
substance/preparation
Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
USA
815.968.0747 or
1.800.874.3723
CHEMTREC:
800.424.9300
OUTSIDE US:
703.527.3887
Substance/preparation Preparation :
Section 2. Composition, Information on Ingredients
CAS number Ingredient name % EC number Classification
Adipic Dihydrazide 111-69-3 0.1 - 1 203-896-3 T+; R27
T; R23/25
Xi; R36/37/38
Physical/chemical hazards Not applicable.
Eye contact. Ingestion.
Emergency overview
Medical conditions aggravated
by overexposure
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Not available. Over-exposure signs/symptoms
Section 3. Hazards identification
Routes of entry
Carcinogenic effects CARCINOGENIC EFFECTS: Classified None. by OSHA, None. by NIOSH [Agarose]. Classified None. by NIOSH
[Adipic Dihydrazide].
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Classified POSSIBLE for human [Adipic Dihydrazide].
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
No specific hazard.
Classification Xn; R21
United States
Europe
Potential acute health effects
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Eyes
Skin
Inhalation
Ingestion
Potential chronic health effects
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Human health hazards
Environmental hazards Not applicable.
Harmful in contact with skin.
See toxicological Information (section 11)
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Get medical attention if symptoms appear.
Skin contact
Ingestion
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation
occurs.
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing
before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Slightly hazardous in case of inhalation.
Slightly hazardous in case of ingestion.
Irritation of the product in case of skin contact: Not available. Sensitization of the product: Not available. Skin contact
Not available. Eye contact
Inhalation
Aggravating conditions Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
First-Aid measures
If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical
attention.
Notes to physician Not available.
Not available. Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye contact
Section 4. First aid measures
Notice to reader Get immediate medical attention.
Hazardous thermal decomposition
products
Not applicable.
Non-flammable.
Not applicable.
Use an extinguishing agent suitable for surrounding fires.
Not applicable.
Section 5. Fire fighting measures
Flammability of the product
Flash Points
Fire hazards in presence of various
substances
Fire fighting media and instructions
Not applicable. Protective clothing (fire)
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
Section 6. Accidental release measures
Small spill and leak Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Environmental precautions and
clean-up methods
Personal precautions Safety glasses. Lab coat. Gloves.
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Keep container tightly closed. Keep container in a cool, well-ventilated area.
Avoid prolonged contact with eyes, skin, and clothing. Wash thoroughly after handling.
Section 7. Handling and storage
Handling
Storage
Suitable / Not suitable
Packaging materials
Use original container.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
United States
Ingredient Name Occupational Exposure Limits
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective occupational exposure limits.
Section 8. Exposure Controls, Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Hands
Protective Clothing
(Pictograms)
Gloves.
Lab coat.
Splash goggles.
Respiratory Respirator is not needed under normal and intended conditions of use, if exposures are kept below established limits.
Adipic Dihydrazide Arbeidsinspectie (Netherlands).
TGG: 8.8 mg/m3
Netherlands
Turkey
Adipic Dihydrazide NIOSH (United States).
TWA: 4 ppm
The lowest known value is 100°C (212°F) (water).
Liquid. (Suspension.)
Neutral.
May start to solidify at 0°C (32°F) based on data for: water.
The only known value is 1 (Water = 1) (water).
The highest known value is 0.62 (Air = 1) (water).
The highest known value is 2.3 kPa (17.5 mm Hg) (at 20°C) (water).
See solubility in water, methanol, acetone.
The lowest known value is 374.2°C (705.6°F) (water).
Not applicable.
Not available.
Not available.
White.
Boiling/condensation point
Melting/freezing point
0.36 (water) compared to (n-BUTYL ACETATE=1)
Dynamic: The highest known value is 1 cP (water)
Physical State
Molecular weight
pH (1% Soln/Water)
Critical temperature
Specific Gravity
Vapor pressure
Vapor density
Evaporation rate
Viscosity
Dispersion properties
Odor
Taste
Color
Section 9. Physical and chemical properties
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Easily soluble in methanol, acetone.
Insoluble in cold water, hot water, diethyl ether.
Solubility
The product is stable.
Reactive with oxidizing agents, acids.
Will not occur.
Sodium azide may react with lead or copper plumbing to form highly explosive metal azides. (Sodium Azide)
Section 10. Stability and reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous polymerization
Hazardous Decomposition
Products
Not available.
water:
ORAL (LD50): Acute: >90000 mg/kg [ Rat].
Agarose
LD50: Not available.
LC50: Not available.
Adipic Dihydrazide:
ORAL (LD50): Acute: 155 mg/kg [Rat]. 22 mg/kg [Rabbit]. 25 mg/kg
[Cat.].
VAPOR (LC50): Acute: 1710 mg/m3 4 hour(s) [Rat].
Sodium Azide:
ORAL (LD50): Acute: 27 mg/kg [Rat]. 27 mg/kg [Mouse]. 23.7 mg/kg
[Birds.].
DERMAL (LD50): Acute: 20 mg/kg [Rabbit]. 50 mg/kg [Rat].
Slightly hazardous in case of ingestion, of inhalation.
CARCINOGENIC EFFECTS: Classified None. by OSHA, None. by NIOSH [Agarose]. Classified None. by NIOSH [Adipic
Dihydrazide].
TERATOGENIC EFFECTS: Classified POSSIBLE for human [Adipic Dihydrazide].
Not available.
To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated. (Agarose)
Can cause CNS depression. Exposure can cause coughing, chest pains, difficulty in breathing. Exposure can cause
stomach pains, vomiting and diarrhea. May be fatal, if the substance enters bloodstream. (Adipic Dihydrazide)
Section 11. Toxicological information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Skin
Ingestion
Inhalation No known significant effects or critical hazards.
No known significant effects or critical hazards.
No known significant effects or critical hazards.
Over-exposure
signs/symptoms
No known significant effects or critical hazards. Carcinogenicity
No known significant effects or critical hazards. Mutagenicity
No known significant effects or critical hazards. Reproductive toxicity
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological information
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Mobility Not available. :
Species Period
Ecotoxicity data
Ingredient name
LogPow BCF
Persistence/degradability
Bioaccumulative potential
Other ecological information
Other adverse effects : No known significant effects or critical hazards.
Ingredient name
Ingredient name BOD5 COD
Ingredient name Aquatic half-life Photolysis
Not available. Waste Stream
Section 13. Disposal considerations
Denmark – Carcinogenic waste Not available.
Not available. Sweden - thermoset plastic
waste
Not available. European waste catalogue
(EWC)
The classification of the product may meet the criteria for a hazardous waste Hazardous waste
Austria - Waste catalogue Not available.
Denmark - Waste card number Not available.
Denmark - Waste group Not available.
Sweden - Waste group Not available.
Norway - Waste number Not available.
Switzerland - Waste code Not available.
The generation of waste should be avoided or minimized wherever possible. Avoid dispersal of
spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal of this
product, solutions and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local authority
requirements.
Methods of disposal
Norway - Hazardous waste The classification of the product may meet the criteria for a hazardous waste
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport information
Section 15. Regulatory information
R21- Harmful in contact with skin.
S2- Keep out of the reach of children. S36/37- Wear suitable protective clothing and gloves. S46- If
swallowed, seek medical advice immediately and show this container or label.
Label Requirements
(Europe)
1
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U.S. Federal Regulations
Pennsylvania RTK: Adipic Dihydrazide; Sodium Azide: (environmental hazard, generic environmental hazard)
Florida: Sodium Azide
Minnesota: Adipic Dihydrazide; Sodium Azide
Massachusetts RTK: Adipic Dihydrazide; Sodium Azide
New Jersey: Adipic Dihydrazide; Sodium Azide
-- HCS Classification
TSCA 8(b) inventory: Adipic Dihydrazide; Agarose; Sodium Azide; water
TSCA 8(d) H and S data reporting: Sodium Azide
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State Regulations
CEPA DSL: Adipic Dihydrazide; Agarose; Sodium Azide; water
Australia (NICNAS): Sodium Azide
Germany water class: Adipic Dihydrazide; Agarose; Sodium Azide
Japan (METI): Sodium Azide
Korea (TCCL): Sodium Azide
Philippines (RA6969): Sodium Azide
WHMIS (Canada) Not controlled under WHMIS (Canada).
R21- Harmful in contact with skin. DSCL (EEC)
International Regulations
Not available. EINECS
International Lists
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
Harmful
Pennsylvania RTK: Adipic Dihydrazide; Sodium Azide: (environmental hazard, generic environmental
hazard)
Florida: Sodium Azide
Minnesota: Adipic Dihydrazide; Sodium Azide
Massachusetts RTK: Adipic Dihydrazide; Sodium Azide
New Jersey: Adipic Dihydrazide; Sodium Azide
State regulations
Not available.
Section 16. Other information
References
Hazardous Material
Information System
(U.S.A.)
National Fire Protection
Association (U.S.A.)
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
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0
0
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Health
Fire hazard
Reactivity
Personal protection
0
0
0 Health
Special
Instability
Flammability
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Version 0.01
Date of previous issue No Previous
Validation
Validated by MSDS Administrator on 5/16/2006. Verified by MSDS Administrator.
Printed 5/16/2006.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its
subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and
should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that
exist.
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Full text of classifications
referred to in sections 2 and 3
- Europe
Full text of R phrases referred
to in sections 2 and 3 -
Europe
T+ - Very toxic
T - Toxic
Xn - Harmful
Xi - Irritant
R27- Very toxic in contact with skin.
R23/25- Toxic by inhalation and if swallowed.
R21- Harmful in contact with skin.
R36/37/38- Irritating to eyes, respiratory system and skin.