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MSDS Safety Information 
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NAME: CELL CONDITIONING SOLUTION (CC2)

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MATERIAL SAFETY DATA SHEET
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
VENTANA MEDICAL SYSTEMS INC. EMERGENCY TELEPHONE NUMBER:
1910 E. Innovation Park Drive (800) 424-9300 (USA/Canada)
Tucson, Arizona 85755 (CHEMTREC)
(520) 887-2155 +1 (703) 527-3887 (International)
MSDS NUMBER: 00231367
SUBSTANCE: Cell Conditioning Solution (CC2)
TRADE NAMES/SYNONYMS:
CC2 (Pre-dilute)
PRODUCT NUMBER(S): 950-123
PRODUCT USE: clinical/research
CREATION DATE: Oct 27 2005
REVISION DATE: Mar 05 2009
2. HAZARDS IDENTIFICATION
NFPA RATINGS (SCALE 0-4): HEALTH=2 FIRE=0 REACTIVITY=0
EC CLASSIFICATION:
No classification assigned.
EMERGENCY OVERVIEW:
COLOR: colorless
PHYSICAL FORM: liquid
ODOR: faint odor
MAJOR HEALTH HAZARDS: respiratory tract irritation, skin irritation, eye irritation, central nervous
system depression, nerve damage, kidney damage
POTENTIAL HEALTH EFFECTS:
INHALATION:
SHORT TERM EXPOSURE: irritation, allergic reactions, headache, drowsiness, dizziness, loss of
coordination, blood disorders
LONG TERM EXPOSURE: irritation, allergic reactions, headache
SKIN CONTACT:
SHORT TERM EXPOSURE: irritation, allergic reactions
LONG TERM EXPOSURE: irritation, allergic reactions
EYE CONTACT:
SHORT TERM EXPOSURE: irritation
LONG TERM EXPOSURE: irritation
INGESTION:
SHORT TERM EXPOSURE: nausea, vomiting, stomach pain, difficulty breathing, headache, drowsiness,
dizziness, disorientation, hyperactivity, emotional disturbances, hallucinations, tremors, loss of coordination,
visual disturbances, lung congestion, heart damage, kidney damage, liver damage, nerve damage, brain
damage, convulsions, coma
LONG TERM EXPOSURE: kidney damage
3. COMPOSITION, INFORMATION ON INGREDIENTS
COMPONENT: NON-HAZARDOUS
CAS NUMBER: Not assigned.
EC NUMBER: Not assigned.
PERCENTAGE: 60-100
EC CLASSIFICATION: No classification assigned.
COMPONENT: ETHYLENE GLYCOL
CAS NUMBER: 107-21-1
EC NUMBER (EINECS): 203-473-3
PERCENTAGE: 3-7
EC CLASSIFICATION: Xn
RISK PHRASES: 22
COMPONENT: DODECYL SODIUM SULFATE
CAS NUMBER: 151-21-3
EC NUMBER (EINECS): 205-788-1
PERCENTAGE: <1
EC CLASSIFICATION: Xn
RISK PHRASES: 22-36-38
COMPONENT: HYDROUS CITRIC ACID
CAS NUMBER: 5949-29-1
EC NUMBER: Not assigned.
PERCENTAGE: <1
EC CLASSIFICATION: Xi
RISK PHRASES: 37-38-41
COMPONENT: SODIUM METABISULFITE
CAS NUMBER: 7681-57-4
EC NUMBER (EINECS): 231-673-0
PERCENTAGE: <1
EC CLASSIFICATION: Xn; Xi
RISK PHRASES: 22-31-41
4. FIRST AID MEASURES
INHALATION: If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not
breathing. If breathing is difficult, oxygen should be administered by qualified personnel. Get immediate
medical attention.
SKIN CONTACT: Wash contaminated areas with soap and water. Thoroughly clean and dry contaminated
clothing before reuse. Get medical attention, if needed.
EYE CONTACT: Flush eyes with plenty of water for at least 15 minutes. Then get immediate medical
attention.
INGESTION: If a large amount is swallowed, get medical attention.
NOTE TO PHYSICIAN: For inhalation, consider oxygen.
5. FIRE FIGHTING MEASURES
FIRE AND EXPLOSION HAZARDS: Negligible fire hazard.
EXTINGUISHING MEDIA: Use extinguishing agents appropriate for surrounding fire.
FIRE FIGHTING: Move container from fire area if it can be done without risk. Avoid inhalation of
material or combustion by-products.
SENSITIVITY TO MECHANICAL IMPACT: Not sensitive
SENSITIVITY TO STATIC DISCHARGE: Not sensitive
FLASH POINT: not flammable
HAZARDOUS COMBUSTION PRODUCTS:
Thermal decomposition or combustion products: oxides of carbon
6. ACCIDENTAL RELEASE MEASURES
OCCUPATIONAL RELEASE:
Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for
disposal.
7. HANDLING AND STORAGE
STORAGE: Store and handle in accordance with all current regulations and standards. Store at room
temperature. Avoid direct sunlight. Protect from freezing. See original container for storage
recommendations. Keep separated from incompatible substances.
8. EXPOSURE CONTROLS, PERSONAL PROTECTION
EXPOSURE LIMITS:
ETHYLENE GLYCOL:
50 ppm (125 mg/m3) OSHA ceiling (vacated by 58 FR 35338, June 30, 1993)
100 mg/m3 ACGIH ceiling (aerosol)
26 mg/m3 (10 ml/m3) DFG MAK (peak limitation category - I, with excursion factor of 2) (cutaneous
absorption danger)
52 mg/m3 (20 ppm) EC OEL TWA (skin) (IOELV)
104 mg/m3 (40 ppm) EC OEL STEL (skin) (IOELV)
10 mg/m3 UK WEL TWA (particulate) (skin)
52 mg/m3 (20 ppm) UK WEL TWA (vapor) (skin)
104 mg/m3 (40 ppm) UK WEL STEL (vapor) (skin)
VENTILATION: Provide adequate ventilation. Ensure compliance with applicable exposure limits.
EYE PROTECTION: Safety glasses or goggles are recommended when there is a potential for eye contact.
Provide an emergency eye wash fountain and quick drench shower in the immediate work area.
CLOTHING: Lab coat or apron.
GLOVES: Wear appropriate chemical resistant gloves.
PROTECTIVE MATERIAL TYPES: latex, nitrile
RESPIRATOR: No respirator is required under normal conditions of use.
9. PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE: liquid
APPEARANCE: clear
COLOR: colorless
ODOR: faint odor
BOILING POINT: Not available
FREEZING POINT: Not available
VAPOR PRESSURE: Not available
VAPOR DENSITY: Not available
SPECIFIC GRAVITY: Not available
WATER SOLUBILITY: miscible
PH: 6
VOLATILITY: Not available
ODOR THRESHOLD: Not available
EVAPORATION RATE: Not available
COEFFICIENT OF WATER/OIL DISTRIBUTION: Not available
10. STABILITY AND REACTIVITY
REACTIVITY: Stable at normal temperatures and pressure.
CONDITIONS TO AVOID: None reported.
INCOMPATIBILITIES: oxidizing materials, bases, acids
HAZARDOUS DECOMPOSITION:
Thermal decomposition or combustion products: oxides of carbon
POLYMERIZATION: Will not polymerize.
11. TOXICOLOGICAL INFORMATION
ETHYLENE GLYCOL:
IRRITATION DATA: 0.012 percent/3 day(s) eyes-rat; 555 mg open skin-rabbit mild; 500 mg/24 hour(s)
eyes-rabbit mild; 100 mg/1 hour(s) eyes-rabbit mild; 0.012 ppm/3 day(s) eyes-rabbit; 1440 mg/6 hour(s)
eyes-rabbit moderate
TOXICITY DATA: 9530 ul/kg skin-rabbit LD50; 4700 mg/kg oral-rat LD50
CARCINOGEN STATUS: ACGIH: A4 -Not Classifiable as a Human Carcinogen
LOCAL EFFECTS:
Irritant: inhalation, skin, eye
ACUTE TOXICITY LEVEL:
Moderately Toxic: ingestion
Slightly Toxic: dermal absorption
TARGET ORGANS: nervous system, kidneys
12. ECOLOGICAL INFORMATION
Not available
13. DISPOSAL CONSIDERATIONS
Dispose in accordance with all applicable regulations.
14. TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION: Not regulated.
CANADIAN TRANSPORTATION OF DANGEROUS GOODS: Not regulated.
LAND TRANSPORT ADR: Not regulated.
LAND TRANSPORT RID: Not regulated.
AIR TRANSPORT IATA: Not regulated.
AIR TRANSPORT ICAO: Not regulated.
MARITIME TRANSPORT IMDG: Not regulated.
15. REGULATORY INFORMATION
U.S. REGULATIONS:
CERCLA SECTIONS 102a/103 HAZARDOUS SUBSTANCES (40 CFR 302.4):
ETHYLENE GLYCOL: 5000 LBS RQ
SARA TITLE III SECTION 302 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355 Subpart
B): Not regulated.
SARA TITLE III SECTION 304 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355 Subpart
C): Not regulated.
SARA TITLE III SARA SECTIONS 311/312 HAZARDOUS CATEGORIES (40 CFR 370 Subparts B
and C):
ACUTE: Yes
CHRONIC: Yes
FIRE: No
REACTIVE: No
SUDDEN RELEASE: No
SARA TITLE III SECTION 313 (40 CFR 372.65):
ETHYLENE GLYCOL
STATE REGULATIONS:
California Proposition 65: Not regulated.
CANADIAN REGULATIONS:
WHMIS CLASSIFICATION: D2A, D2B.
EUROPEAN REGULATIONS:
EC CLASSIFICATION (CALCULATED):
No classification assigned.
16. OTHER INFORMATION
EC RISK PHRASES:
R 22 Harmful if swallowed.
R 31 Contact with acids liberates toxic gas.
R 36 Irritating to eyes.
R 37 Irritating to respiratory system.
R 38 Irritating to skin.
R 41 Risk of serious damage to eyes.
“RTECS®” is a United States trademark owned and licensed under authority of the U.S. Government, by
and through Symyx Software, Inc. Portions ©Copyright 2001, U.S. Government. All rights reserved.
Limitations: The information and recommendations set forth in this MSDS are believed to be correct
as of this date. Ventana Medical Systems, Inc. makes no warranty with respect to the content of this
MSDS and disclaims all liability from reliance thereon.