5000111 - DC Protein Assay Reagent A Product: Bio-Rad DC Protein Assay Kit 1 Product code: 5000111 Substance no. description qty. symbols 5000113 DC Protein Assay Reagent A 1 C 5000114 DC Protein Assay Reagent B 1 - 5000115 DC Protein Assay Reagent S 1 - 5000005 Protein Standard I Globulin 1 - Material Safety Data Sheet Printing date 03/13/2003Reviewed on 08/07/2002 1 Identification of substance: Product details: Trade name: DC Protein Assay Reagent A Catalog or product number: 5000113, 9702088 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: Bio-Rad Laboratories, Life Science Group 2000 Alfred Nobel Drive Hercules, California 94547 (510)741-1000 Information department: Technical services, customer support. Emergency information: 1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT. 510-741-1000 2 Composition/Information on components: Chemical characterization: CAS No. Description: 7732-18-5 water Identification number(s): EINECS Number: 231-791-2 Chemical characterization Listing of dangerous and non-hazardous components: 1310-73-2 sodium hydroxide 2.5-5 % C; R 35 EINECS: 215-185-5 3 Hazards identification Emergency overview: C Corrosive Information pertaining to particular dangers for man and environment R 34 Causes burns. NFPA ratings (scale 0-4) Health = 1 Fire = 0 Reactivity = 0 4 First aid measures General information Immediately remove any clothing soiled by the product. After inhalation In case of unconsciousness place patient stably in side position for transportation. After skin contact Immediately wash with water and soap and rinse thoroughly. After eye contact Rinse opened eye for several minutes under running water. Then consult a doctor. After swallowing Drink copious amounts of water and provide fresh air. Immediately call a doctor. 5 Fire fighting measures Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: No special measures required. 6 Accidental release measures Person-related safety precautions: Wear protective equipment (See section 8). Keep unprotected persons away. Measures for environmental protection: Prevent seepage into sewage system, workpits and cellars. Do not allow to enter sewers/ surface or ground water. Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Use neutralizing agent. Dispose contaminated material as waste according to item 13. Ensure adequate ventilation. 7 Handling and storage Handling Information for safe handling: No special measures required. No special precautions are necessary if used correctly. Information about protection against explosions and fires: No special measures required. Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: Keep receptacle tightly sealed. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: Not required. Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment General protective and hygienic measures Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. Breathing equipment: Not required. Protection of hands: Protective gloves. Synthetic gloves Material of gloves Synthetic gloves Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Tightly sealed goggles. 9 Physical and chemical properties: General Information Form: liquid Color: Light blue Odor: Odorless Value/Range Unit Method Change in condition Melting point/Melting range: 0 ° C Boiling point/Boiling range: 100 ° C Flash point: Not applicable Danger of explosion: Product does not present an explosion hazard. Vapor pressure: at 20 ° C 23 hPa Density: at 20 ° C 1 g/cm³ Solubility in / Miscibility with Water: Fully miscible Not miscible or difficult to mix pH-value: at 20 ° C 13.6 Viscosity: dynamic: at 20 ° C 1 mPas Organic solvents: 0.0 % Water: 95.3 % Solids content: 4.7 % 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Dangerous reactions No dangerous reactions known Dangerous products of decomposition: No dangerous decomposition products known 11 Toxicological information Acute toxicity: LD/LC50 values for hazardous components per OSHA criteria: 1310-73-2 sodium hydroxide Oral: LD50: 2000 mg/kg (rat) Primary irritant effect: on the skin: Caustic effect on skin and mucous membranes. on the eye: Strong caustic effect. Sensitization: No sensitizing effects known. Additional toxicological information: Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of esophagus and stomach. 12 Ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Must not reach bodies of water or drainage ditch undiluted or unneutralized. 13 Disposal considerations Product: Recommendation Must not be disposed of together with household garbage. Do not allow product to reach sewage system. Hand over to hazardous waste disposers. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. 14 Transport information DOT regulations: Hazard class: - Land transport ADR/RID (cross-border) ADR/RID class: - Maritime transport IMDG: IMDG Class: - Marine pollutant: No Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: - 15 Regulations SARA (Superfund Amendents and Reauthorization Act of 1986 - USA) Section 302/304 (40CFR355.30 / 40CFR355.40): Substance not listed. Section 313 (40CFR372.65): Substance is not listed. TSCA (Toxic Substances Control Act): Substance is listed. California Proposition 65: Chemicals known to cause cancer: Substance is not listed. Chemicals known to cause reproductive toxicity: Substance is not listed. Cancerogenity categories EPA (Environmental Protection Agency) Substance is not listed. IARC (International Agency for Research on Cancer) Substance is not listed. NTP (National Toxicology Program) Substance is not listed. TLV (Threshold Limit Value established by ACGIH) Substance is not listed. MAK (German Maximum Workplace Concentration) Substance is not listed. NIOSH-Ca (National Institute for Occupational Safety and Health) Substance is not listed. OSHA-Ca (Occupational Safety & Health Administration) Substance is not listed. Markings according to EU guidelines: The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials Code letter and hazard designation of product: C Corrosive Risk phrases: 34 Causes burns. Safety phrases: 20 When using do not eat or drink. 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. 45 In case of accident or if you feel unwell, seek medical advice immediately. 60 This material and its container must be disposed of as hazardous waste. National regulations Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water. 16 Other information: This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing MSDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000 Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000 Material Safety Data Sheet Printing date 03/13/2003Reviewed on 03/13/2003 1 Identification of substance: Product details: Trade name: DC Protein Assay Reagent B Catalog or product number: 5000114, 9702089 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: Bio-Rad Laboratories, Life Science Group 2000 Alfred Nobel Drive Hercules, California 94547 (510)741-1000 Information department: Technical services, customer support. Emergency information: 1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT. 510-741-1000 2 Composition/Information on components: Chemical characterization: CAS No. Description: 7732-18-5 water Identification number(s): EINECS Number: 231-791-2 Chemical characterization Listing of dangerous and non-hazardous components: 7782-91-4 molybdic acid 0.1-1.0 % T; R 23/24/25 EINECS: 231-970-5 RTECS: QA 4725000 3 Hazards identification Information pertaining to particular dangers for man and environment · not applicable NFPA ratings (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 4 First aid measures General information No special measures required. After inhalation Supply fresh air; consult doctor in case of complaints. After skin contact Generally the product does not irritate the skin. After eye contact Rinse opened eye for several minutes under running water. After swallowing Induce vomiting and call for medical help. 5 Fire fighting measures Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: No special measures required. 6 Accidental release measures Person-related safety precautions: Not required Measures for environmental protection: No special measures required. Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Additional information: No dangerous substances are released. 7 Handling and storage Handling Information for safe handling: No special measures required. No special precautions are necessary if used correctly. Information about protection against explosions and fires: No special measures required. Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: 7664-38-2 phosphoric acid PEL: 1 mg/m³ REL: Short-term value: 3 mg/m³ Long-term value: 1 mg/m³ TLV: Short-term value: 3 mg/m³ Long-term value: 1 mg/m³ 7647-01-0 hydrogen chloride PEL: Short-term value: C 7 mg/m³, C 5 ppm REL: Short-term value: C 7 mg/m³, C 5 ppm TLV: Short-term value: C 7.5 mg/m³, C 5 ppm NIC-C 2; C 2.98; NIC-A4 Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed. Breathing equipment: Not required. Protection of hands: Synthetic gloves Material of gloves Synthetic gloves Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Goggles recommended during refilling. 9 Physical and chemical properties: General Information Form: liquid Color: Colorless Odor: Odorless Value/Range Unit Method Change in condition Melting point/Melting range: 0 ° C Boiling point/Boiling range: 100 ° C Flash point: Not applicable Danger of explosion: Product does not present an explosion hazard. Vapor pressure: at 20 ° C 23 hPa Density: at 20 ° C 1 g/cm³ Solubility in / Miscibility with Water: Fully miscible Not miscible or difficult to mix pH-value: at 20 ° C 2.0 Viscosity: dynamic: at 20 ° C 1 mPas Organic solvents: 0.0 % Water: 98.4 % Solids content: 1.4 % 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Dangerous reactions No dangerous reactions known Dangerous products of decomposition: No dangerous decomposition products known 11 Toxicological information Acute toxicity: Primary irritant effect: on the skin: No irritant effect. on the eye: No irritant effect. Sensitization: No sensitizing effects known. Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. The substance is not subject to classification according to the latest version of the EU lists. 12 Ecological information: General notes: Generally not hazardous for water. 13 Disposal considerations Product: Recommendation Hand over to hazardous waste disposers. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. 14 Transport information DOT regulations: Hazard class: - Land transport ADR/RID (cross-border) ADR/RID class: - Maritime transport IMDG: IMDG Class: - Marine pollutant: No Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: - 15 Regulations SARA (Superfund Amendents and Reauthorization Act of 1986 - USA) Section 302/304 (40CFR355.30 / 40CFR355.40): Substance not listed. Section 313 (40CFR372.65): Substance is not listed. TSCA (Toxic Substances Control Act): 7732-18-5 water California Proposition 65: Chemicals known to cause cancer: Substance is not listed. Chemicals known to cause reproductive toxicity: Substance is not listed. Cancerogenity categories EPA (Environmental Protection Agency) Substance is not listed. IARC (International Agency for Research on Cancer) 7647-01-0 hydrogen chloride: 3 NTP (National Toxicology Program) Substance is not listed. TLV (Threshold Limit Value established by ACGIH) Substance is not listed. MAK (German Maximum Workplace Concentration) Substance is not listed. NIOSH-Ca (National Institute for Occupational Safety and Health) Substance is not listed. OSHA-Ca (Occupational Safety & Health Administration) Substance is not listed. Markings according to EU guidelines: The substance is not subject to classification according to EU lists and other sources of literature known to us. Observe the general safety regulations when handling chemicals The product is not subject to identification regulations under EU Directives and the Ordinance on Hazardous Materials (GefStoffV). Safety phrases: 60 This material and its container must be disposed of as hazardous waste. National regulations Water hazard class: Generally not hazardous for water. 16 Other information: This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing MSDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000 Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000 Material Safety Data Sheet Printing date 03/13/2003Reviewed on 03/13/2003 1 Identification of substance: Product details: Trade name: DC Protein Assay Reagent S Catalog or product number: 5000115, 9702090 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: Bio-Rad Laboratories, Life Science Group 2000 Alfred Nobel Drive Hercules, California 94547 (510)741-1000 Information department: Technical services, customer support. Emergency information: 1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT. 510-741-1000 2 Composition/Information on components: Chemical characterization Description: Mixture of the substances listed below with non-hazardous additions. Listing of dangerous and non-hazardous components: 7732-18-5 water 50-100 % EINECS: 231-791-2 RTECS: ZC 0110000 151-21-3 sodium dodecyl sulphate 5-10 % Xn; R 21/22-36/38 EINECS: 205-788-1 RTECS: WT 1050000 3 Hazards identification Information pertaining to particular dangers for man and environment · not applicable Classification system The classification was made according to the latest editions of the EU- lists, and expanded upon from company and literature data. NFPA ratings (scale 0-4) Health = 1 Fire = 0 Reactivity = 0 OSHA hazard ratings Health 0: Minimal Hazard. Fire 0: Minimal hazard. Reactivity 0: Minimal hazard. 4 First aid measures General information No special measures required. After inhalation Supply fresh air; consult doctor in case of complaints. After skin contact Generally the product does not irritate the skin. After eye contact Rinse opened eye for several minutes under running water. After swallowing Induce vomiting and call for medical help. 5 Fire fighting measures Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: No special measures required. 6 Accidental release measures Person-related safety precautions: Not required Measures for environmental protection: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Additional information: No dangerous substances are released. 7 Handling and storage Handling Information for safe handling: No special measures required. No special precautions are necessary if used correctly. Information about protection against explosions and fires: No special measures required. Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed. Breathing equipment: Not required. Protection of hands: Synthetic gloves Material of gloves Synthetic gloves Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Goggles recommended during refilling. 9 Physical and chemical properties: General Information Form: liquid Color: Transparent Odor: Odorless Value/Range Unit Method Change in condition Melting point/Melting range: undetermined Boiling point/Boiling range: 100 ° C Flash point: Not applicable Auto igniting: Product is not selfigniting. Danger of explosion: Product does not present an explosion hazard. Vapor pressure: at 20 ° C 23.0 hPa Density: at 20 ° C 0.964 g/cm³ Solubility in / Miscibility with Water: Fully miscible Solvent content: Organic solvents: 0.0 % Water: 92.5 % Solids content: 7.5 % 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Dangerous reactions No dangerous reactions known Dangerous products of decomposition: No dangerous decomposition products known 11 Toxicological information Acute toxicity: LD/LC50 values for hazardous components per OSHA criteria: 151-21-3 sodium dodecyl sulphate Oral: LD50: 1288 mg/kg (rat) Primary irritant effect: on the skin: No irritant effect. on the eye: No irritant effect. Sensitization: No sensitizing effects known. Additional toxicological information: The product is not subject to classification according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. 12 Ecological information: General notes: Water hazard class 2 (Self-assessment): hazardous for water. Do not allow product to reach ground water, water course or sewage system. Danger to drinking water if even small quantities leak into the ground. 13 Disposal considerations Product: Recommendation Hand over to hazardous waste disposers. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agent: Water, if necessary with cleansing agents. 14 Transport information DOT regulations: Hazard class: - Land transport ADR/RID (cross-border) ADR/RID class: - Maritime transport IMDG: IMDG Class: - Marine pollutant: No Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: - 15 Regulations SARA (Superfund Amendents and Reauthorization Act of 1986 - USA) Section 302/304 (40CFR355.30 / 40CFR355.40): None of the ingredients is listed. Section 313 (40CFR372.65): None of the ingredients is listed. TSCA (Toxic Substances Control Act): All ingredients are listed. California Proposition 65: Chemicals known to cause cancer: The product does not contain listed components. Chemicals known to cause reproductive toxicity: The product does not contain listed components. Cancerogenity categories EPA (Environmental Protection Agency) None of the ingredients is listed. IARC (International Agency for Research on Cancer) None of the ingredients is listed. NTP (National Toxicology Program) None of the ingredients is listed. TLV (Threshold Limit Value established by ACGIH) None of the ingredients is listed. MAK (German Maximum Workplace Concentration) None of the ingredients is listed. NIOSH-Ca (National Institute for Occupational Safety and Health) None of the ingredients is listed. OSHA-Ca (Occupational Safety & Health Administration) None of the ingredients is listed. Markings according to EU guidelines: Observe the general safety regulations when handling chemicals The product is not subject to identification regulations under EU Directives and the Ordinance on Hazardous Materials (GefStoffV). Safety phrases: 60 This material and its container must be disposed of as hazardous waste. National regulations Water hazard class: Water hazard class 2 (Self-assessment): hazardous for water. 16 Other information: This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing MSDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000 Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000 Material Safety Data Sheet Printing date 03/13/2003Reviewed on 03/13/2003 1 Identification of substance: Product details: Trade name: Protein Standard I Globulin Catalog or product number: 5000005 Application of the substance / the preparation Laboratory chemicals Manufacturer/Supplier: Bio-Rad Laboratories, Life Science Group 2000 Alfred Nobel Drive Hercules, California 94547 (510)741-1000 Information department: Technical services, customer support. Emergency information: 1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT. 510-741-1000 2 Composition/Information on components: Chemical characterization: CAS No. Description: 9007-83-4 gamma globulin Identification number(s): EINECS Number: 285-365-6 3 Hazards identification Information pertaining to particular dangers for man and environment · not applicable NFPA ratings (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 4 First aid measures General information No special measures required. After inhalation Supply fresh air; consult doctor in case of complaints. After skin contact Generally the product does not irritate the skin. After eye contact Rinse opened eye for several minutes under running water. After swallowing Induce vomiting and call for medical help. 5 Fire fighting measures Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Protective equipment: No special measures required. 6 Accidental release measures Person-related safety precautions: Not required Measures for environmental protection: No special measures required. Measures for cleaning/collecting: Pick up mechanically. Additional information: No dangerous substances are released. 7 Handling and storage Handling Information for safe handling: No special measures required. No special precautions are necessary if used correctly. Information about protection against explosions and fires: No special measures required. Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 8 Exposure controls and personal protection Additional information about design of technical systems: No further data; see item 7. Components with limit values that require monitoring at the workplace: Not required. Additional information: The lists that were valid during the creation were used as basis. Personal protective equipment General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed. Protection of hands: Synthetic gloves Material of gloves Synthetic gloves Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Not required. 9 Physical and chemical properties: General Information Form: Flakes Color: Light yellow Odor: Odorless Value/Range Unit Method Change in condition Melting point/Melting range: undetermined Boiling point/Boiling range: undetermined Flash point: Not applicable Flammability (solid, gaseous) Product is not flammable. Danger of explosion: Product does not present an explosion hazard. Density: Not determined Solubility in / Miscibility with Water: Fully miscible Soluble Organic solvents: 0.0 % Solids content: 100.0 % 10 Stability and reactivity Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. Dangerous reactions No dangerous reactions known Dangerous products of decomposition: No dangerous decomposition products known 11 Toxicological information Acute toxicity: Primary irritant effect: on the skin: No irritant effect. on the eye: No irritant effect. Sensitization: No sensitizing effects known. Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. The substance is not subject to classification according to the latest version of the EU lists. 12 Ecological information: General notes: Generally not hazardous for water. 13 Disposal considerations Product: Recommendation Hand over to hazardous waste disposers. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agent: Water, if necessary with cleansing agents. 14 Transport information DOT regulations: Hazard class: - Land transport ADR/RID (cross-border) ADR/RID class: - Maritime transport IMDG: IMDG Class: - Marine pollutant: No Air transport ICAO-TI and IATA-DGR: ICAO/IATA Class: - 15 Regulations SARA (Superfund Amendents and Reauthorization Act of 1986 - USA) Section 302/304 (40CFR355.30 / 40CFR355.40): Substance not listed. Section 313 (40CFR372.65): Substance is not listed. TSCA (Toxic Substances Control Act): Substance is not listed. California Proposition 65: Chemicals known to cause cancer: Substance is not listed. Chemicals known to cause reproductive toxicity: Substance is not listed. Cancerogenity categories EPA (Environmental Protection Agency) Substance is not listed. IARC (International Agency for Research on Cancer) Substance is not listed. NTP (National Toxicology Program) Substance is not listed. TLV (Threshold Limit Value established by ACGIH) Substance is not listed. MAK (German Maximum Workplace Concentration) Substance is not listed. NIOSH-Ca (National Institute for Occupational Safety and Health) Substance is not listed. OSHA-Ca (Occupational Safety & Health Administration) Substance is not listed. Markings according to EU guidelines: The substance is not subject to classification according to EU lists and other sources of literature known to us. Observe the general safety regulations when handling chemicals The product is not subject to identification regulations under EU Directives and the Ordinance on Hazardous Materials (GefStoffV). National regulations Water hazard class: Generally not hazardous for water. 16 Other information: This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing MSDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000 Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000