MATERIAL SAFETY DATA SHEET 3. HAZARDS IDENTIFICATION INHALATION: May cause irritation to respiratory tract and mucous membranes, sore throat, coughing, dizziness, shortness of breath and fainting. May be absorbed through inhalation. INGESTION: May cause breathlessness, pulmonary edema and rapid heartbeat within 5 minutes. Nausea, vomiting, headache, restlessness and diarrhea may occur within 15 minutes. Other symptoms may include low blood pressure, abnormal breathing, reduced body temperature, reduced body pH, convulsions, collapse and death. EYE CONTACT: Causes irritation, redness, pain and blurred vision. SKIN CONTACT: Causes redness, irritation and pain. May be absorbed through skin. MEDICAL CONDITIONS POSSIBLY AGGRAVATED: None known. 4. FIRST AID MEASURES INHALATION: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. INGESTION: DO NOT induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. EYE CONTACT: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately. SKIN CONTACT: Wipe off affected area and flush with plenty of soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention. Wash clothing and shoes thoroughly before reuse. 1. IDENTIFICATION OF SUBSTANCE/PREPARATION AND OF COMPANY/UNDERTAKING This Material Safety Data Sheet is for the following products: MANUFACTURER: Product Name Gamma-clone Control Gamma-clone Control Anti -D IgM, IgG Anti -D IgM, IgG Anti -D IgM, IgG Anti -c Gamma-clone Anti -e Gamma-clone PHONE: 800-326-4262 Gamma Biologicals Inc. 3700 Mangum Road Houston, TX 77092-5497 Product Name Product Code Size 1x10mL Anti -Mg Gamma-clone Gamma Elu-Kit II Elu-Kit II Wash Soln Anti -D IgM Anti -D IgM Anti -D IgM 1x5mL 1x10mL 10x10mL 10x10mL 50x10mL 0420401 0420410 0420501 0420510 0420550 0004231 0004241 1x5mL UEL: N/A Product Code Size 1x5mL kit 1x50mL 1x10mL 10x10mL 50x10mL 0004434 0007861 0007860 0430101 0430110 0430150 ACGIH-STEL/CEIL(C) N/A N/A N/A N/A N/A C 0.11 as HN3 vapor C 0.29 as NaN3 FLASH POINT: N/A 2. COMPOSITION/INFORMATION ON INGREDIENTS INGREDIENTS Glycine Bovine Albumin Sodium Azide OSHA PEL-TWA ACGIH-TWA TLV CONCENTRATION CAS NUMBER N/A N/A N/A 1-10% 1-10% 0.1% 56-40-6 9048-46-8 26628-22-8 LEL: N/A 5. FIRE-FIGHTING MEASURES ESTIMATED EXPLOSIVE LIMITS (% By volume in air): MSDS NO: 11 PRODUCT TYPE: MEDICAL DIAGNOSTIC REAGENT REVISION DATE: 1/22/2003 PAGE 1 OF 3 PAGE 2 OF 3 MSDS NO: 11 PRODUCT TYPE: MEDICAL DIAGNOSTIC REAGENT REVISION DATE: 1/22/2003 pH: 6-8** ** PH for Elu-kit is 2-9 MATERIAL SAFETY DATA SHEET EXTINGUISHING MEDIA: Use appropriate extinguishing media for surrounding fire: dry chemical, carbon dioxide, water spray or regular foam. SPECIAL FIRE FIGHTING PROCEDURES: Wear appropriate personal protective equipment. Fight fires only if properly trained. Move containers from fire area if it can be accomplished without risk. Use water to keep containers cool. Dike fire control water. UNUSUAL HAZARDS: Avoid breathing vapors or dusts. Keep upwind. 6. ACCIDENTAL RELEASE MEASURES STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED: Remove all sources of ignition. Do not touch spilled or material. Stop the release if you can do it without risk. Isolate the area and deny entry. Absorb the spill and place used absorbent material into approved containers for later disposal. Decontaminate the area with an approved disinfectant. Cover the area with paper towels and pour disinfectant over the area. Wipe the area until clean and dry. 7. HANDLING AND STORAGE HANDLING: Food and drink should not be consumed or tobacco products used, nor cosmetics applied in areas where chemicals are stored or handled. STORAGE: Store away from incompatible substances. Store in tightly closed containers. Avoid contact with open wounds and body fluids. Wash thoroughly after handling and before eating, drinking or smoking. Observe, federal, state and local regulations. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION EYE PROTECTION: Use chemical safety goggles and/or full face shield where splashing of the solution is possible. Maintain eyewash fountain and quick drench facilities in the work area. CLOTHING/GLOVES: Clothing such as gowns, aprons, or lab coats should be worn when working with this material. Protective gloves should be worn while handling materials and/or surfaces, which are potentially infectious. HEAD/ FOOT PROTECTION: Hood, surgical caps, boots and shoe covers should be worn in areas with significant quantities of infectious materials. RESPIRATORY PROTECTION: A NIOSH/MSHA approved respirator should be worn where airborne exposures may exceed OSHA/ACGIH exposure limits. VENTILATION: Provide sufficient mechanical (general and/or local exhaust) ventilation to maintain exposure below permissible air concentrations. 9. PHYSICAL AND CHEMICAL PROPERTIES SPECIFIC GRAVITY: % VOLATILE BY WEIGHT: EVAPORATION RATE: 212 °F 32 °F 18 mm Hg 1 (H2O=1) N/A N/A SOLUBILITY IN WATER: N/A 0 lbs/gal (EPA Ref. Methods 24) BOILING POINT: MELTING POINT: VAPOR PRESSURE: VAPOR DENSITY: N/A (Air=1) VOLATILE ORGANIC COMPOUNDS (VOC): APPEARANCE/ODOR: Clear amber liquid 10. STABILITY AND REACTIVITY STABILITY: Stable CONDITIONS TO AVOID: Fire and excessive heat. May decompose in heat. HAZARDOUS POLYMERIZATION: Will not occur. INCOMPATIBILITY: Benzoyl chloride, potassium hydroxide, bromine, carbon disulfide, chromyl chloride, copper, dibromomalononitrile, dimethyl sulfate, lead, barium carbonate, sulfuric acid, nitric acid, strong acids and substances that react violently with water. HAZARDOUS DECOMPOSITION PRODUCTS: Sodium azide when heated to decomposition liberates nitrogen gas and sodium, which is explosive. Carbon dioxide and carbon monoxide may form when bovine albumin is heated to decomposition. MATERIAL SAFETY DATA SHEET ACUTE EFFECTS: This product is manufactured from human blood and therefore must be considered to be capable of transmitting disease. The substance irritates the eyes, the skin and the respiratory tract. Exposure above Occupational Exposure Limits could cause effects on the nervous system. Glycine is a non-essential amino acid that is relatively non-toxic. Extremely high particulate concentrations may cause coughing and eye irritation. If large quantities are ingested, nausea may occur. CHRONIC EFFECTS: No information found. LISTED CARCINOGENS: None. 11. TOXICOLOGICAL INFORMATION No data available. 12. ECOLOGICAL INFORMATION WASTE DISPOSAL: Disposal must be at an approved waste disposal facility and in accordance with applicable Federal, State and Local laws and regulations. Contact the District Director of the Environmental Protection Agency and/or state regulatory agency for appropriate requirements. 13. DISPOSAL CONSIDERATIONS The information contained herein is based on data considered accurate and is offered at no charge. No warranty is expressed or implied regarding the accuracy of this data. Liability is expressly disclaimed for loss or injury arising out of use of this information or the use of any materials designated. 16. OTHER INFORMATION R-Phrase: 22 Symbol: Xn 14. TRANSPORTATION INFORMATION HAZARD CLASS: 6.1 ID#: IN1687 DOT PROPER SHIPPING NAME: Sodium Azide 15. REGULATORY INFORMATION None TSCA: All components of this product are listed on the TSCA inventory. CERCLA REPORTABLE QUANTITY: None CLEAN AIR AMENDMENTS-HAZARDOUS AIR POLLUTANTS (HAPS): CALIFORNIA STATE PROPOSITION 65: S-Phrases: N/A PAGE 3 OF 3 None MSDS NO: 11 PRODUCT TYPE: MEDICAL DIAGNOSTIC REAGENT REVISION DATE: 1/22/2003 PACKING GROUP: II SARA Title III: Section 302: None Section 312: None Section 313: None