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@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Product Name Glycohemoglobin Normal Control
Part Number 451680
Doc. ID 451680-75 AB
Issued (year/month/day)
Revised (year/month/day) 2007/09/04
Product Use For In Vitro Diagnostic Use. See product literature for details.
Series Name I.D.-ZONE?
Manufacturer Beckman Coulter, Inc.
4300 Harbor Blvd.
Fullerton, CA 92835-3100, U.S.A.
ECREP Address:
Beckman Coulter Ireland, Inc.
Mervue Business Park,
Mervue, Galway, Ireland 353 91 774068
Distributor and
Emergency Phone No. 
 Refer to attached list, Document ID: 472050, for local distributor and
emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Ethylene Glycol 107-21-1 = 25 Xn;R 22 Yes Exempt
See Section 15 Regulatory Information for additional information on hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Red; Translucent; Liquid; Musty
Nonflammable solution.
May cause irritation of skin, eyes, mucous
membranes and upper respiratory tract.
Harmful if swallowed.
Contains material of human origin.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health
Effects Summary
May cause irritation of respiratory tract, skin and eyes; central nervous system
depression; severe kidney damage and reproductive effects.
This product contains material of human origin and should be considered as
potentially capable of transmitting infectious diseases.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard
Classifications
EU:
Xn;R22
WHMIS:
Exempt
US OSHA:
Hazardous
?2007 Beckman Coulter, Inc.
Global MSDS – English
Glycohemoglobin Normal Control MSDS # 451680-75 AB Page 2 of 5
Section 3 Hazards Identification (Continued)
Beckman Coulter Safety
Rating
Flammability (Section V): 0
Health (Section XI): 2
Reactivity with Water (Section X): 0
Contact (Section VIII): 2
Code
0=none
1=slight
2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical
attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and
Explosion Hazards
None identified.
Hazardous Combustion
Products
No combustion products posing significant hazards are expected from this product.
Protective Equipment
for Firefighters
Self-contained breathing apparatus is recommended for firefighters in all chemical fire
situations.
Section 6 Accidental Release Measures
Personal Precautions This product contains material of human origin and should be handled as though capable
of transmitting infectious diseases. Universal precautions should be followed during
clean up procedures.
Spill and Leak
Procedures
As a precautionary measure, treat spilled material with a 1:10 bleach/water solution.
Absorb liquid and place in container suitable for disposal. Avoid generation of
aerosols during clean up. Comply with applicable waste disposal regulations.
Environmental
Precautions
Contain spill to prevent migration.
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious diseases.
Universal precautions should be followed when using this product.
Recommended Storage
Conditions
Keep away from incompatible material (see Section 10).
To maintain efficacy, store according to the instructions in the product labeling.
Glycohemoglobin Normal Control MSDS # 451680-75 AB Page 3 of 5
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH:
Ethylene Glycol 100 mg/m3 Ceiling (aerosol only)
DFG MAK:
Ethylene Glycol 10 ppm MAK; 26 mg/m3 MAK; 20 ppm Peak; 52 mg/m3 Peak; skin notation
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as Nitrile or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Red
Transparency Translucent
Odor Musty
Odor Threshold Not applicable
pH 7.0
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.113 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous
Incompatibilities
Strong acids
Strong bases
Strong oxidizers
Glycohemoglobin Normal Control MSDS # 451680-75 AB Page 4 of 5
Section 10 Stability and Reactivity (Continued)
Hazardous
Decomposition Products
No decomposition products posing significant hazards would be expected from this
product.
Conditions to Avoid Avoid contact with incompatible materials.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Ethylene Glycol Oral LD50 Rat: 4000 mg/kg; Dermal LD50 Rabbit: 9530 µL/kg
Primary Routes
of Exposure
Common routes of entry include inhalation, ingestion and eye/skin contact. Specific
paths of concern for potentially infectious materials are skin puncture, contact with
broken skin, contact with mucous membranes and inhalation of aerosolized material.
Potential Effects of
Acute Exposure
Exposure to ethylene glycol may result in eye and respiratory tract irritation.
Inhalation of mists and absorption through skin may cause central nervous system
depression. Ingestion may cause severe central nervous system depression, kidney
failure, heart failure or respiratory arrest.
This product contains material of human origin and should be considered as
potentially capable of transmitting infectious diseases.
Potential Effects of
Chronic Exposure
Prolonged or repeated exposure to ethylene glycol may result in mild irritation
and central nervous system depression; symptoms may include throat irritation,
drowsiness, headache and backache. Contact with skin and eyes may result in
dermatitis and conjunctivitis with red, scaly skin and inflamed eyes. Animal studies
indicate repeated ingestion of small amounts can cause severe kidney damage.
Symptoms of
Overexposure
Symptoms may include redness and itching or burning of the skin and eyes, and
irritation or burning sensation of the upper respiratory tract with coughing and difficulty
in breathing.
Carcinogenicity This product does not contain a reportable concentration (= 0.1%) of any ingredient
listed as carcinogen by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported in animal studies.
Conditions Aggravated
by Exposure
Individuals with skin, eye, or respiratory tract disorders may find these conditions
aggravated by exposure to this product.
Individuals with central nervous system, cardiovascular, or kidney disorders may find
these conditions aggravated by exposure to this product.
Section 12 Ecological Information
Ecotoxicity Ethylene Glycol: 96 Hr LC50 Oncorhynchus mykiss: 41000 mg/L; 96 Hr LC50 Lepomis
macrochirus: 27500 mg/L; 96 Hr LC50 Oncorhynchus mykiss: 40761 mg/L [static]; 96 Hr
LC50 Pimephales promelas: 49000 mg/L [static]; 96 Hr LC50 Poecilia reticulata: 16000
mg/L [static]
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Glycohemoglobin Normal Control MSDS # 451680-75 AB Page 5 of 5
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 Ethylene Glycol is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s,
40 CFR 302.4
Ethylene Glycol is listed.
California Proposition 65 No ingredients listed
Massachusetts MSL Ethylene Glycol is listed.
New Jersey Dept. of
Health RTK List
Ethylene Glycol is listed.
Pennsylvania RTK Ethylene Glycol is listed.
EU Labeling Classification
Classification Risk and Safety Phrases
Xn
Harmful
R22 Harmful if swallowed.
S37/39 Wear suitable gloves and eye/face protection.
Canada
This product is exempt from WHMIS label and MSDS requirements.
PIN: Not applicable
Ingredients on Ingredient
Disclosure List:
Ethylene Glycol
Ingredients with unknown
toxicological properties:
Product is exempt
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANYWAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.