SIGMA-ALDRICH Material Safety Data Sheet Date Printed: 09/AUG/2005 Date Updated: 17/MAY/2005 Version 1.4 According to 91/155/EEC 1 - Product and Company Information Product Name HEXADIMETHRINE BROMIDE, >=95% Product Number 107689 Company Sigma-Aldrich Pty. Ltd. 12 Anella Avenue Castle Hill NSW 2154 Technical Phone # +61 2 9841 0555 (1800 800 097) Fax +61 2 9841 0500 (1800 800 096) Emergency Phone # +44 8701906777 (1800 448 465) 2 - Composition/Information on Ingredients Product Name CAS # EC no Annex I Index Number HEXADIMETHRINE BROMIDE 28728-55-4 None None Synonyms 6,3-Ionene bromide * Polybrene * Polybrene 3 - Hazards Identification SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT Not hazardous according to Directive 67/548/EEC. 4 - First Aid Measures AFTER INHALATION If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. AFTER SKIN CONTACT In case of contact, immediately wash skin with soap and copious amounts of water. AFTER EYE CONTACT In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. AFTER INGESTION If swallowed, wash out mouth with water provided person is conscious. Call a physician. 5 - Fire Fighting Measures EXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. SPECIAL RISKS Specific Hazard(s): Emits toxic fumes under fire conditions. SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. 6 - Accidental Release Measures PROCEDURE(S) OF PERSONAL PRECAUTION(S) Exercise appropriate precautions to minimize direct contact with skin or eyes and prevent inhalation of dust. METHODS FOR CLEANING UP Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete. 7 - Handling and Storage HANDLING Directions for Safe Handling: Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure. STORAGE Conditions of Storage: Keep tightly closed. Incompatible Materials: Moisture. SPECIAL REQUIREMENTS: Hygroscopic. 8 - Exposure Controls / Personal Protection ENGINEERING CONTROLS Safety shower and eye bath. Mechanical exhaust required. GENERAL HYGIENE MEASURES Wash thoroughly after handling. PERSONAL PROTECTIVE EQUIPMENT Respiratory Protection: Wear dust mask. Hand Protection: Protective gloves. Eye Protection: Chemical safety goggles. 9 - Physical and Chemical Properties Appearance Physical State: Solid Property Value At Temperature or Pressure pH N/A BP/BP Range N/A MP/MP Range N/A Flash Point N/A Flammability N/A Autoignition Temp N/A Oxidizing Properties N/A Explosive Properties N/A Explosion Limits N/A Vapor Pressure N/A SG/Density N/A Partition Coefficient N/A Viscosity N/A ALDRICH - 107689 www.sigma-aldrich.com Page 2 Vapor Density N/A Saturated Vapor Conc. N/A Evaporation Rate N/A Bulk Density N/A Decomposition Temp. N/A Solvent Content N/A Water Content N/A Surface Tension N/A Conductivity N/A Miscellaneous Data N/A Solubility Solubility in Water:0.1 g/ml H2O 10 - Stability and Reactivity STABILITY Stable: Stable. Conditions of Instability: Moisture sensitive. HAZARDOUS DECOMPOSITION PRODUCTS Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen bromide gas. HAZARDOUS POLYMERIZATION Hazardous Polymerization: Will not occur 11 - Toxicological Information RTECS NUMBER: TQ2655000 ACUTE TOXICITY LD50 Intravenous Rat 20 MG/KG LD50 Oral Mouse > 1000 mg/kg LD50 Intraperitoneal Mouse 30 MG/KG LD50 Intravenous Mouse 28 MG/KG SIGNS AND SYMPTOMS OF EXPOSURE To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. ROUTE OF EXPOSURE Skin Contact: May cause skin irritation. Skin Absorption: May be harmful if absorbed through the skin. Eye Contact: May cause eye irritation. Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract. Ingestion: May be harmful if swallowed. ALDRICH - 107689 www.sigma-aldrich.com Page 3 TARGET ORGAN INFORMATION Blood. Kidneys. 12 - Ecological Information No data available. 13 - Disposal Considerations SUBSTANCE DISPOSAL Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. 14 - Transport Information RID/ADR Non-hazardous for road transport. IMDG Non-hazardous for sea transport. IATA Non-hazardous for air transport. 15 - Regulatory Information Not hazardous according to Directive 67/548/EEC. COUNTRY SPECIFIC INFORMATION Germany WGK: 3 (Self classification) 16 - Other Information WARRANTY The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Inc., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only. DISCLAIMER For R&D use only. Not for drug, household or other uses. ALDRICH - 107689 www.sigma-aldrich.com Page 4