======================================================= MSDS Safety Information ======================================================= NAME: IRON REAGENT B ======================================================= SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING VENTANA MEDICAL SYSTEMS, INC. 1910 E. Innovation Park Drive Tucson, Arizona 85755 U.S.A. +1 (520) 887-2155 (800) 227-2155 (U.S.) EC REP Roche Diagnostics GmbH Roche Diagnostics Australia Pty. Ltd Sandhofer Strasse 116 31 Victoria Avenue D-68305 Mannheim Castle Hill, NSW, 2154 Germany Australia Phone: 61-2-9860-2329 Fax: 61-2-9860-2133 Emergency Phone Number: 61-2-9759-4301 SDS NUMBER: 00231574 SUBSTANCE: Iron Reagent B PRODUCT NUMBER(S): 1522300 PRODUCT USE: clinical/research CREATION DATE: Feb 07 2006 REVISION DATE: Mar 05 2009 2. HAZARDS IDENTIFICATION NFPA RATINGS (SCALE 0-4): HEALTH=1 FIRE=0 REACTIVITY=0 EC CLASSIFICATION: Xi Irritant RISK PHRASES: R 36/37/38 Irritating to eyes, respiratory system and skin. EMERGENCY OVERVIEW: COLOUR: colourless PHYSICAL FORM: liquid ODOUR: odourless MAJOR HEALTH HAZARDS: No significant target effects reported. POTENTIAL HEALTH EFFECTS: INHALATION: SHORT TERM EXPOSURE: no information on significant adverse effects LONG TERM EXPOSURE: no information on significant adverse effects SKIN CONTACT: SHORT TERM EXPOSURE: no information on significant adverse effects LONG TERM EXPOSURE: no information on significant adverse effects EYE CONTACT: SHORT TERM EXPOSURE: no information on significant adverse effects LONG TERM EXPOSURE: no information on significant adverse effects INGESTION: SHORT TERM EXPOSURE: no information on significant adverse effects LONG TERM EXPOSURE: no information on significant adverse effects 3. COMPOSITION, INFORMATION ON INGREDIENTS COMPONENT: Non-hazardous CAS NUMBER: Not assigned. EC NUMBER: Not assigned. PERCENTAGE: 60-100 EC CLASSIFICATION: No classification assigned. COMPONENT: Hydrochloric acid, 1N CAS NUMBER: Not assigned. EC NUMBER: Not assigned. PERCENTAGE: <2 EC CLASSIFICATION: Xn; C; Xi RISK PHRASES: 20-35-37 4. FIRST AID MEASURES INHALATION: If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not breathing. Get immediate medical attention. SKIN CONTACT: Wash contaminated areas with soap and water. Thoroughly clean and dry contaminated clothing before reuse. Get medical attention, if needed. EYE CONTACT: Flush eyes with plenty of water for at least 15 minutes. Then get immediate medical attention. INGESTION: If a large amount is swallowed, get medical attention. 5. FIRE FIGHTING MEASURES FIRE AND EXPLOSION HAZARDS: Negligible fire hazard. EXTINGUISHING MEDIA: Use extinguishing agents appropriate for surrounding fire. FIRE FIGHTING: Move container from fire area if it can be done without risk. Avoid inhalation of material or combustion by-products. SENSITIVITY TO MECHANICAL IMPACT: Not sensitive SENSITIVITY TO STATIC DISCHARGE: Not sensitive FLASH POINT: not flammable HAZARDOUS COMBUSTION PRODUCTS: Thermal decomposition or combustion products: hydrogen chloride gas 6. ACCIDENTAL RELEASE MEASURES OCCUPATIONAL RELEASE: Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for disposal. 7. HANDLING AND STORAGE STORAGE: Store and handle in accordance with all current regulations and standards. Store at room temperature. See original container for storage recommendations. Keep separated from incompatible substances. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION EXPOSURE LIMITS: Iron Reagent B: No occupational exposure limits established. VENTILATION: Provide adequate ventilation. Ensure compliance with applicable exposure limits. EYE PROTECTION: Safety glasses or goggles are recommended when there is a potential for eye contact. Provide an emergency eye wash fountain and quick drench shower in the immediate work area. CLOTHING: Lab coat or apron. GLOVES: Wear appropriate chemical resistant gloves. PROTECTIVE MATERIAL TYPES: latex, vinyl, nitrile RESPIRATOR: No respirator is required under normal conditions of use. 9. PHYSICAL AND CHEMICAL PROPERTIES PHYSICAL STATE: liquid APPEARANCE: clear COLOUR: colourless ODOUR: odourless BOILING POINT: Not available FREEZING POINT: Not available VAPOUR PRESSURE: Not available VAPOUR DENSITY: Not available SPECIFIC GRAVITY: Not available WATER SOLUBILITY: miscible PH: acidic VOLATILITY: Not available ODOUR THRESHOLD: Not available EVAPORATION RATE: Not available COEFFICIENT OF WATER/OIL DISTRIBUTION: Not available 10. STABILITY AND REACTIVITY REACTIVITY: Stable at normal temperatures and pressure. CONDITIONS TO AVOID: None reported. INCOMPATIBILITIES: bases, amines, alkali metals, copper, copper alloys, aluminium, steel HAZARDOUS DECOMPOSITION: Thermal decomposition or combustion products: hydrogen chloride gas POLYMERISATION: Will not polymerise. 11. TOXICOLOGICAL INFORMATION Not available 12. ECOLOGICAL INFORMATION Not available 13. DISPOSAL CONSIDERATIONS Dispose in accordance with all applicable regulations. 14. TRANSPORT INFORMATION U.S. DEPARTMENT OF TRANSPORTATION: Not regulated. CANADIAN TRANSPORTATION OF DANGEROUS GOODS: Not regulated. LAND TRANSPORT ADR: Not regulated. LAND TRANSPORT RID: Not regulated. AIR TRANSPORT IATA: Not regulated. AIR TRANSPORT ICAO: Not regulated. MARITIME TRANSPORT IMDG: Not regulated. 15. REGULATORY INFORMATION U.S. REGULATIONS: CERCLA SECTIONS 102a/103 HAZARDOUS SUBSTANCES (40 CFR 302.4): Hydrogen chloride (Hydrochloric acid): 5000 LBS RQ (liquid) SARA TITLE III SECTION 302 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355 Subpart B): Not regulated. SARA TITLE III SECTION 304 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355 Subpart C): Not regulated. SARA TITLE III SARA SECTIONS 311/312 HAZARDOUS CATEGORIES (40 CFR 370 Subparts B and C): ACUTE: No CHRONIC: No FIRE: No REACTIVE: No SUDDEN RELEASE: No SARA TITLE III SECTION 313 (40 CFR 372.65): Not regulated. STATE REGULATIONS: California Proposition 65: Not regulated. CANADIAN REGULATIONS: WHMIS CLASSIFICATION: Not a Controlled Product under Canada's Workplace Hazardous Material Information System. EUROPEAN REGULATIONS: EC CLASSIFICATION (CALCULATED): Xi Irritant DANGER/HAZARD SYMBOL: EC RISK AND SAFETY PHRASES: R 36/37/38 Irritating to eyes, respiratory system and skin. S 24/25 Avoid contact with skin and eyes. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 60 This material and its container must be disposed of as hazardous waste. 16. OTHER INFORMATION EC RISK PHRASES: R 20 Harmful by inhalation. R 35 Causes severe burns. R 36/37/38 Irritating to eyes, respiratory system and skin. R 37 Irritating to respiratory system. Limitations: The information and recommendations set forth in this SDS are believed to be correct as of this date. Ventana Medical Systems, Inc. makes no warranty with respect to the content of this SDS and disclaims all liability from reliance thereon.