Material Safety Data Sheet Isobutyric acid ACC# 72274 Section 1 - Chemical Product and Company Identification MSDS Name: Isobutyric acid Catalog Numbers: AC122520000, AC122520010, AC122520200, AC122520250, AC122522500, AC122525000 AC122525000, AC219960000, AC219961000, AC219965000 Synonyms: 2-Methylpropionic acid; Isopropylformic acid; Dimethylacetic acid; 2-Methylpropanoic acid; Isobutanoic acid. Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410 For information in North America, call: 800-ACROS-01 For emergencies in the US, call CHEMTREC: 800-424-9300 Section 2 - Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS 79-31-2 Isobutyric acid >99 201-195-7 Section 3 - Hazards Identification EMERGENCY OVERVIEW Appearance: clear, colorless liquid. Flash Point: 55 deg C. Danger! Causes eye and skin burns. Causes digestive and respiratory tract burns. Flammable liquid and vapor. Harmful if swallowed or absorbed through the skin. Stench. Target Organs: Respiratory system, gastrointestinal system, eyes, skin. Potential Health Effects Eye: Causes eye burns. Vapors cause eye irritation. Skin: Harmful if absorbed through the skin. Causes skin burns. Not expected to cause an allergic skin reaction. Ingestion: Harmful if swallowed. May cause severe and permanent damage to the digestive tract. Inhalation: May cause severe respiratory tract irritation and possible burns. Vapor or mist is irritating to the mucous membranes and upper respiratory tract. Chronic: Chronic exposure may cause effects similar to those of acute exposure. Section 4 - First Aid Measures Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid immediately. Skin: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse. Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - Fire Fighting Measures General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Flash Point: 55 deg C ( 131.00 deg F) Autoignition Temperature: 482 deg C ( 899.60 deg F) Explosion Limits, Lower:2% Upper: 9.2% NFPA Rating: (estimated) Health: 3; Flammability: 2; Instability: 0 Section 6 - Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Section 7 - Handling and Storage Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep away from heat, sparks and flame. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Do not breathe vapor or mist. Storage: Keep away from sources of ignition. Keep container closed when not in use. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs Isobutyric acid none listed none listed none listed OSHA Vacated PELs: Isobutyric acid: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - Physical and Chemical Properties Physical State: Liquid Appearance: clear, colorless Odor: pungent odor - butter-like - unpleasant odor - strong rancid - stench pH: 2.9 (0.1M aq soln) Vapor Pressure: 1.5 mm Hg @ 20 deg C Vapor Density: 3.04 (air=1) Evaporation Rate:Not available. Viscosity: 1.3 cps @ 25 deg C Boiling Point: 153-155 deg C Freezing/Melting Point:-47 deg C Decomposition Temperature:Not available. Solubility: 20 g/100 ml @ 20°C Specific Gravity/Density:0.949 Molecular Formula:C4H8O2 Molecular Weight:88.11 Section 10 - Stability and Reactivity Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Ignition sources, confined spaces. Incompatibilities with Other Materials: Metals, strong oxidizing agents, strong bases. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - Toxicological Information RTECS#: CAS# 79-31-2: NQ4375000 LD50/LC50: CAS# 79-31-2: Oral, rat: LD50 = 280 uL/kg; Skin, rabbit: LD50 = 500 uL/kg; . 280 uL/kg = 266 mg/kg, 500 uL/kg = 475 mg/kg, Skin irritation(rabbit): moderate, Skin irritation (guinea pig): severe. Eye irritation (rabbit): severe, Skin sensitization (guinea pig):none (Eastman Chemical Company) Carcinogenicity: CAS# 79-31-2: Not listed by ACGIH, IARC, NTP, or CA Prop 65. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Mutagenicity: No information available. Neurotoxicity: No information available. Other Studies: Section 12 - Ecological Information No information available. Section 13 - Disposal Considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. Section 14 - Transport Information US DOT Canada TDG Shipping Name: ISOBUTYRIC ACID Isobutyric Acid Hazard Class: 3 3 UN Number: UN2529 UN2529 Packing Group: III III Section 15 - Regulatory Information US FEDERAL TSCA CAS# 79-31-2 is listed on the TSCA inventory. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. CERCLA Hazardous Substances and corresponding RQs CAS# 79-31-2: 5000 lb final RQ (listed under Butyric acid); 2270 kg final RQ (listed under But SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ. SARA Codes CAS # 79-31-2: immediate, fire. Section 313 No chemicals are reportable under Section 313. Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: CAS# 79-31-2 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE CAS# 79-31-2 can be found on the following state right to know lists: New Jersey, Pennsylvania, Massachusetts. California Prop 65 California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 21/22 Harmful in contact with skin and if swallowed. Safety Phrases: WGK (Water Danger/Protection) CAS# 79-31-2: 1 Canada - DSL/NDSL CAS# 79-31-2 is listed on Canada's DSL List. Canada - WHMIS This product has a WHMIS classification of B3, D1B, E. This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations. Canadian Ingredient Disclosure List CAS# 79-31-2 is listed on the Canadian Ingredient Disclosure List. Section 16 - Additional Information MSDS Creation Date: 10/26/1998 Revision #5 Date: 4/27/2007 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.