STERLING WINTHROP SANOFI WINTH -- ISUPREL ======================================================= MSDS Safety Information ======================================================= FSC: 6505 NIIN: 00-689-5522 MSDS Date: 12/09/1992 MSDS Num: BXNXP Product ID: ISUPREL MFN: 01 Responsible Party Cage: GO573 Name: STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU Address: 90 PARK AVE City: NEW YORK NY 10016-1302 Info Phone Number: 212-907-2000/800-223-5511 Emergency Phone Number: 212-907-2000/800-223-5511 Review Ind: Y Published: Y ======================================================= Preparer Co. when other than Responsible Party Co. ======================================================= Cage: GO573 Assigned Ind: Y Name: STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU Address: 90 PARK AVE City: NEW YORK NY 10016-1302 ======================================================= Contractor Summary ======================================================= Cage: GO573 Name: STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU Address: 90 PARK AVE City: NEW YORK NY 10016-1302 Phone: 212-907-2000/800-223-5511 Cage: 63240 Name: WINTHROP PHARMACEUTICALS Address: 90 PARK AVE City: NEW YORK NY 10156 Phone: 212-907-2000 ======================================================= Item Description Information ======================================================= Item Name: ISOPROTERENOL HYDROCHLORIDE INJECTION,USP Unit of Issue: PG Quantitative Expression: 00000000010EA UI Container Qty: 1 ======================================================= Ingredients ======================================================= Name: BISULFITE ======================================================= Health Hazards Data ======================================================= Route Of Entry Inds - Inhalation: NO Skin: NO Ingestion: NO Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO Effects of Exposure: THIS IS A PHARMACEUTICAL MATERIAL AVAILABLE ONLY W/A PRESCRIPTION. USE ONLY AS DIRECTED. MAY CAUSE ALLERGIC TYPE REACTIONS FROM BISULFITE, ADVERSE NERVOUS SYSTEM, CARDIOVASCULAR & GI SYSTEM EFFECTS. O VERDOSE IS CHARACTERIZED BY TACHYCARDIA/OTHER ARRHYTHMIAS/PALPITATIONS/ANGINA/HYPOTENSION/HYPERTENSION. Explanation Of Carcinogenicity: NONE Signs And Symptions Of Overexposure: NERVOUSNESS, HEADACHE, DIZZINESS, ADAMS-STOKES ATTACKS, PULMONARY EDEMA, FLUSHING OF THE SKIN, SWEATING, MILD TREMORS, WEAKNESS. First Aid: EYES: FLUSH W/PLENTY OF WATER FOR 15 MINS. SKIN: WASH THOROUGHLY W/SOAP & WATER. OBTAIN MEDICAL ATTENTION IN ALL CASES. ======================================================= Handling and Disposal ======================================================= Spill Release Procedures: CONTAIN BY PLACING PAPER TOWELS/SUITABLE ABSORBENT MATERIAL AROUND EDGES & WORK INWARD. CAREFULLY SCOOP UP INTO A PROPERLY LABELED WASTE CONTAINER FOR DISPOSAL. WASH AREA TO REMOVE FROM SURFACES. Waste Disposal Methods: DISPOSE OF IAW/FEDERAL, STATE & LOCAL REGULATIONS. Other Precautions: KEEP THIS & ALL DRUGS OUT OF REACH OF CHILDREN. AVOID EYE CONTACT. ======================================================= Fire and Explosion Hazard Information ======================================================= Extinguishing Media: USE MEDIAL APPROPRIATE FOR SURROUNDING FIRES. Fire Fighting Procedures: USE NORMAL FIRE FIGHTING GEAR. ======================================================= Control Measures ======================================================= Ventilation: NORMAL VENTILATION Eye Protection: NONE NORMALLY REQUIRED. Work Hygienic Practices: WASH THOROUGHLY AFTER HANDLING. USE GOOD PERSONAL HYGIENE. ======================================================= Physical/Chemical Properties ======================================================= Solubility in Water: COMPLETE Appearance and Odor: COLORLESS LIQUID ======================================================= Reactivity Data ======================================================= Stability Indicator: YES Hazardous Polymerization Indicator: NO ======================================================= Toxicological Information ======================================================= ======================================================= Ecological Information ======================================================= ======================================================= MSDS Transport Information ======================================================= ======================================================= Regulatory Information ======================================================= ======================================================= Other Information ======================================================= ======================================================= HAZCOM Label ======================================================= Product ID: ISUPREL Cage: GO573 Assigned IND: Y Company Name: STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU Street: 90 PARK AVE City: NEW YORK NY Zipcode: 10016-1302 Health Emergency Phone: 212-907-2000/800-223-5511 Label Required IND: Y Date Of Label Review: 12/16/1998 Status Code: C Label Date: 12/16/1998 Origination Code: G Hazard And Precautions: THIS IS A PHARMACEUTICAL MATERIAL AVAILABLE ONLY W/A PRESCRIPTION. USE ONLY AS DIRECTED. MAY CAUSE ALLERGIC TYPE REACTIONS FROM BISULFITE, ADVERSE NERVOUS SYSTEM, CARDIOVASCULAR & GI SYSTEM EFFECTS. O VERDOSE IS CHARACTERIZED BY TACHYCARDIA/OTHER ARRHYTHMIAS/PALPITATIONS/ANGINA/HYPOTENSION/HYPERTENSION. NERVOUSNESS, HEADACHE, DIZZINESS, ADAMS-STOKES ATTACKS, PULMONARY EDEMA, FLUSHIN G OF THE SKIN, SWEATING, MILD TREMORS, WEAKNESS. ======================================================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever expressly or implied warrants, states, or intends said information to have any application, use or viability by or to any person or persons outside the Department of Defense nor any person or persons contracting with any instrumentality of the United States of America and disclaims all liability for such use. Any person utilizing this instruction who is not a military or civilian employee of the United States of America should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation regardless of similarity to a corresponding Department of Defense or other government situation.