Nacalai USA, Inc.
6640 Lusk Blvd. Suite A200
San Diego, CA 92121, USA
Phone: (858) 404-0403 Fax: (858) 404-0408
MATERIAL SAFETY DATA SHEET
1. PRODUCT IDENTIFICATION
• Trade Name: LDS Sample Buffer (4X), (5X)
• Catalog numbers: NU31002, NU31010, NU35008
• Manufacturer/Supplier: Nacalai USA, Inc.
6640 Lusk Blvd. Suite A200
San Diego, CA 92121, USA
• Information department: Technical Services, customer support.
• Phone: +1 (858) 404-0403
2. COMPOSITION / INFORMATION OF COMPONENTS
Mixture of the substances listed below with non-hazardous additions.
Chemical Name % CAS # EINECS #
Triethanolamine hydrochloride 5 to 15% 637-39-8 211-284-2
Lithium Dodecyl Sulfate 5 to 12% 251-21-3 205-788-1
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3. HAZARDS IDENTIFICATION
Potential Health Effects:
EMERGENCY OVERVIEW
WARNING!
MAY BE HARMFUL. MAY BE IRRITATING.
CONTAINS COMPONENT THAT IS A POSSIBLE CARCINOGEN.
Eye:
Can cause minor irritation, tearing and reddening.
Skin:
This material may cause skin irritation. Reddening, itching and inflammation may result. Not
likely to cause acute or permanent damage.
Inhalation:
May cause irritation to the respiratory tract. This material may cause injury or illness if
inhaled.
Ingestion:
If ingested, this material may be irritating to mouth, throat and gastrointestinal tract. May be
harmful if swallowed.
Special Toxic Effects
Some studies indicate that Triethanolamine Hydrochloride may be a tumor promoter in
laboratory animals. (See Section 11).
CAUTION! THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT
BEEN FULLY INVESTIGATED.
Target Organs:
ND
4. FIRST AID MEASURES
Eye:
Flush eyes with plenty of water for at least 20 minutes retracting eyelids often. Tilt the head
to prevent chemical from transferring to the uncontaminated eye. Get immediate medical
attention.
Skin:
Wash with soap and water under a drench shower. Remove contaminated clothing, launder
immediately and discard contaminated leather goods. Get medical attention immediately.
Inhalation:
Remove to fresh air. If breathing is difficult, have a trained individual administer oxygen. If
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not breathing, give artificial respiration and have a trained individual administer oxygen. Get
medical attention immediately.
Ingestion:
If swallowed, wash out mouth with water provided person is conscious.
Never give anything by mouth to an unconscious person. Get medical attention.
Note to Physician:
Treat symptomatically.
5. FIRE FIGHTING MEASURES
Flashpoint ND
Lower Flammable Limit % ND
Upper Flammable Limit % ND
Autoignition Temperature ND
Extinguishing Media:
Use extinguisher media appropriate for surrounding fire.
Firefighting Techniques / Equipment:
As in any fire, wear self-contained breathing apparatus pressure-demand (MHSA/NIOSH
approved or equivalent) and full protective gear. Evacuate the area and fight fire from a safe
distance.
Hazardous Combustion Products:
MAY EMIT TOXIC FUMES UNDER FIRE CONDITIONS.
6. ACCIDENTAL RELEASE MEASURES
Accidental releases may be subject to special reporting requirements and other regulatory
mandates. Refer to section 8 for personal protection equipment recommendations.
Spill Cleanup:
Exposure to the spilled material may be irritating. Follow personal protective equipment
recommendations found in Section 8 of this MSDS.
7. HANDLING AND STORAGE
Storage pressure: Ambient.
Handling Procedures:
DO NOT GET IN EYES, ON SKIN OR CLOTHING. Wash hands thoroughly before eating,
drinking or smoking.
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Storage Procedures:
Store in a cool location. Isolate from incompatible materials and conditions. Keep
container(s) closed. The material is suitable for most general chemical storage areas,
including refrigerators, but not to be stored with food.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls:
No special exhaust ventilation, process enclosures, or other engineering controls are
necessary when handling or using this product to avoid overexposure.
Personal Protective Equipment:
Eye:
An eye wash station must be available where this product is used. Wear chemically resistant
safety glasses with side shields when handling this product. Wear additional eye protection
such as chemical splash goggles and/or face shield when the possibility exists for eye contact
with splashing or spraying liquid, or airborne material. Do not wear contact lenses. Have an
eye wash station available.
Skin:
Wear protective gloves. Inspect gloves for chemical break-through and replace at regular
intervals. Clean protective equipment regularly. Wash hands and other exposed areas with
mild soap and water before eating, drinking, smoking and when leaving work. Have a safety
shower available.
Respiratory:
No special equipment is required.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance/physical state: Liquid solution / suspension
Odor: No odor.
Boiling point (°C): ND
Melting Point (°C): ND
Solubility in water: ND
pH: 7.6 to 8.4
Vapor Pressure: ND
Vapor Density: ND
Specific Gravity/Density: ND
Octanol/water Partition Coeff: ND
Volatiles: ND
Evaporation Rate: ND
Viscosity: ND
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10. STABILITY AND REACTIVITY
Stability/Incompatibility:
Stable under normal conditions of use. Incompatible with oxidizing agents, acids, acid chlorides
and acid anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, Carbon dioxide. Carbon monoxide.
Hazardous Polymerization:
Will not occur.
11. TOXICOLOGICAL INFORMATION
Only selected toxicological data is presented here. See actual entry in RTECS for complete
information.
CAUTION! THE TOXICOLOGICAL PROPERTIES OF THIS MATERIAL HAVE NOT
BEEN FULLY INVESTIGATED. FOLLOW GOOD LABORATORY PRACTICES WHEN
HANDLING.
FOR PURE TRIETHANOLAMINE-HYDROCHLORIDE:
TUMORIGENIC DATA
Oral TDLo - mouse = Dose/Duration: 123 gm/kg/2.2Y-C, Toxic Effects: Tumorigenic -
Carcinogenic by RTECS criteria, Blood - lymphoma, including Hodgkin's disease, Skin
and Appendages - tumors.
Routes of Exposure
Inhalation, ingestion, skin and eye contact
LD50
NO ORAL LD50 IN RATS INFORMATION IS AVAILABLE.
REGISTRY OF THE TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS)
RTECS # KL9346500 (Ethanol, 2,2',2''-nitrilotris-, hydrochloride)
Carcinogenicity
NOT LISTED BY IARC, NTP OR OSHA AS A CARCINOGEN.
12. ECOLOGICAL INFORMATION
Ecotoxicological Information: DATA NOT YET AVAILABLE.
Environmental Fate (Degradation, Transformation, and Persistence): DATA NOT YET
AVAILABLE.
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13. DISPOSAL CONSIDERATIONS
Waste Disposal
Under RCRA, it is the responsibility of the user of the product to determine, at the time of
disposal, whether the product meets RCRA criteria for hazardous waste.
If the material is determined to be a hazardous waste, the transportation, storage, treatment and
disposal of this waste material must be conducted in compliance with 40 CFR 262, 263, 264, 268
and 270. Disposal can occur only in properly permitted facilities.
Contact your local disposal service provider(s) for appropriate method(s) of disposal.
14. TRANSPORT INFORMATION
Proper Shipping Name: NOT REGULATED
Hazard Class: NA
UN/NA Code: NA
Packaging Group: NA
Reportable Quantity: None
Labels Required: NA
Marine Pollutant (49 CFR 172.101 Appendix B): No
15. REGULATORY INFORMATION
Federal Regulations
All ingredients are listed on Inventory of Existing Chemical Substances under the Toxic
Substances Control Act (TSCA).
INFORMATION FOR PURE TRIETHANOLAMINE-HCL
OEL=MAK
State Regulations
Based on available information, this material does not contain any components currently known
to the State of California to cause cancer, birth defects or reproductive harm at levels, which
would be subject to Proposition 65.
International Regulations
International Phrases
R - 45 May cause cancer.
S - 23 Do not breathe gas/fumes/vapour/spray
24/25 Avoid contact with skin and eyes.
36/37/39 Wear suitable protective clothing, gloves & eye/face protection.
EINECS Numbers: See page 1 of this document.
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SARA TITLE III RATINGS for Triethanolamine-HCl
Immediate
Hazard
Delayed
Hazard
Fire
Hazard
Pressure
Hazard
Reactivity
Hazard
SARA 313
Chemical
- X - - - -
NFPA RATINGS for Tris
Health Flammability Reactivity Special Hazards
- - - -
HMIS Ratings for Tris
Health Flammability Reactivity Personal Protection Equipment
2 0 0 I
16. OTHER INFORMATION
Abbreviations:
ND- Not Determined
NA- Not Applicable
SARA- Superfund and Reauthorization Act
HMIS- Hazard Material Information System
WHMIS- Workplace Hazard Materials Information System
NTP- National Toxicology Program
OSHA- Occupational Health and Safety Administration
IARC- International Agency for Research on Cancer
PROP 65- California Safe Drinking Water and Toxic Enforcement Act 0f 1986
EINECS- European Inventory of Existing Commercial Chemical Substances
This information is based on our present knowledge. However, this shall not constitute a
guarantee for any specific product features and shall not establish a legally valid contractual
relationship.
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