Material Safety Data Sheet **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION **** MSDS Name: Lead citrate, trihydrate, 96% (titr.) Catalog Numbers: AC413060000, AC413061000, AC413065000 Synonyms: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, lead(2+) salt (2:3); 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, lead(2++) salt (2:3); Trilead dicitrate Company Identification (Europe): Acros Organics BVBA Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Company Identification (USA): Acros Organics One Reagent Lane Fairlawn, NJ 07410 For information in North America, call: 800-ACROS-01 For information in Europe, call: 0032(0) 14575211 For emergencies in the US, call CHEMTREC: 800-424-9300 For emergencies in Europe, call: 0032(0) 14575299 **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 512-26-5 |1,2,3-propanetricarboxylic acid, 2-hyd| 96 | 208-141-1 | | |roxy-,lead(2+)salt(2:3) | | | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: T Risk Phrases: 20/22 33 61 62 **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW Harmful by inhalation and if swallowed. Danger of cumulative effects. May cause harm to the unborn child. Possible risk of impaired fertility. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Harmful if absorbed through the skin. Ingestion: May cause severe digestive tract irritation with abdominal pain, nausea, vomiting and diarrhea. May cause headache. Exposure may cause anemia and other blood abnormalities. May cause degenerative brain changes. Ingestion of lead compounds can cause toxic effects in the blood-forming organs, kidneys and central nervous system, Acute lead poisoning can cause muscle weakness, "lead line" on the gums, metallic taste, definite loss of appetite, insomnia, dizziness, high lead levels in blood and urine with shock, coma and death in extreme cases. Inhalation: Harmful if inhaled. May cause effects similar to those described for ingestion. May cause respiratory tract irritation. May cause irritation of the mucous membranes. Chronic: May cause paralysis. Repeated exposure may cause nervous system abnormalities with muscle weakness and damage, motor incoordination, and sensation disturbances. Lead salts have been reported to cross the placeta and induce embryo- and feto- mortality. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Notes to Physician: **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. **** SECTION 7 - HANDLING and STORAGE **** Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Use with adequate ventilation. Storage: Store in a cool, dry place. Keep containers tightly closed. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Personal Protective Equipment Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: A respiratory protection program that meets OSHA's 29 CFR :1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES **** Physical State: Solid Appearance: white Odor: none reported pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility: Not available. Specific Gravity/Density: Not available. Molecular Formula: C12H10O14Pb3.3H2O Molecular Weight: 1053.85 **** SECTION 10 - STABILITY AND REACTIVITY **** Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, lead/lead oxides. Hazardous Polymerization: Has not been reported **** SECTION 11 - TOXICOLOGICAL INFORMATION **** RTECS#: CAS# 512-26-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 1,2,3-propanetricarboxylic acid, 2-hydroxy-,lead(2+)salt(2:3) - ACGIH: A3 - animal carcinogen (listed as ** undefined **). California: carcinogen; initial date 10/1/92 (listed as ** undefined * OSHA: Possible select carcinogen (listed as ** undefined **). IARC: Group 2B carcinogen (listed as ** undefined **). Epidemiology: Repeated exposure to lead has caused many toxic effects including: neurological changes, kidney damage, and blood abnormalities. Teratogenicity: No information available. Reproductive Effects: Reproductive effects have occurred in humans. Neurotoxicity: No information available. Mutagenicity: No information available. Other Studies: No data available. **** SECTION 12 - ECOLOGICAL INFORMATION **** Other No information available. **** SECTION 13 - DISPOSAL CONSIDERATIONS **** Dispose of in a manner consistent with federal, state, and local regulations. **** SECTION 14 - TRANSPORT INFORMATION **** US DOT No information available Canadian TDG No information available. **** SECTION 15 - REGULATORY INFORMATION **** US FEDERAL TSCA CAS# 512-26-5 is listed on the TSCA inventory. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. CAS# 512-26-5 is listed as a Priority Pollutant under the Clean Water Act. CAS# 512-26-5 is listed as a Toxic Pollutant under the Clean Water Act. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE 1,2,3-propanetricarboxylic aci can be found on the following state right to know lists: California, (listed as ** no name **), California, (listed as ** no name **), New Jersey, (listed as ** no name **), Florida, (listed as ** no name **), Pennsylvania, (listed as ** no name **), Minnesota, (listed as ** no name **), Massachusetts. The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act: WARNING: This product contains 1,2,3-propanetricarboxylic acid, 2-hydroxy-,lead(2+)salt(2:3), listed as ` ** undefined **', a chemical known to the state of California to cause cancer. WARNING: This product contains 1,2,3-propanetricarboxylic acid, 2-hydroxy-,lead(2+)salt(2:3), listed as ` ** undefined **', a chemical known to the state of California to cause birth defects or other reproductive harm. California No Significant Risk Level: CAS# 512-26-5: NOEL = 0.5 ug/day (listed under ** no name **) European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 20/22 Harmful by inhalation and if swallowed. R 33 Danger of cumulative effects. R 61 May cause harm to the unborn child. R 62 Possible risk of impaired fertility. Safety Phrases: S 53 Avoid exposure - obtain special instructions before use. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 512-26-5: No information available. United Kingdom Occupational Exposure Limits Canada CAS# 512-26-5 is listed on Canada's DSL List. CAS# 512-26-5 is not listed on Canada's Ingredient Disclosure List. Exposure Limits CAS# 512-26-5 (listed as ** undefined **): OEL-FRANCE:TWA 150 mg/m3 OEL-GERMANY:TWA 0.1 mg/m3 OEL-POLAND:TWA 0.05 mg/m3 **** SECTION 16 - ADDITIONAL INFORMATION **** MSDS Creation Date: 7/08/1999 Revision #1 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------