Conforms to 93/112/EC and ISO 11014-1
Material Safety Data Sheet
M-PER Mammalian Protein Extraction Reagent
6811
1859066
CALL CHEMTREC:
800.424.9300
OUTSIDE US:
202.483.7616
9/2/2003
9/2/2003
Product name
Supplier Manufacturer
Product No.
MSDS#
Validation Date
Print Date In Case of Emergency
Section 1. Chemical Product and Company Identification
Responsible Name Pierce Administration
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Eng
In USA: In Europe:
Pierce Perbio Science
P.O. Box 117 Industriezone III
Rockford, IL 61105 Industrielaan 27
USA 9320 Erembodegem-Aalst
815.968.0747 or Belgium
1.800.874.3723 Tel:+32 53 83 44 04
Fax:+32 53 83 76 38
Pierce Biotechnology
P.O. Box 117
Rockford, IL 61105
USA
815.968.0747 or
1.800.874.3723
1) M-PER Component 1 0.1-1 Not available. Xi R37
Ingredient Name EC Number CAS No. R-Phrases
Substance/Preparation Preparation
% Symbol
:
Section 2. Composition, Information on Ingredients
Physical/chemical hazards
Human health hazards
Environmental hazards Not applicable.
Not applicable.
Not applicable.
Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.
Emergency Overview
Medical Conditions Aggravated
by Overexposure:
Repeated or prolonged exposure is not known to aggravate medical condition.
Not available. Overexposure /Signs/Symptoms
Section 3. Hazards Identification
Routes of Entry
Potential Acute Health Effects
Carcinogenic Effects Data
See Toxicological Information (section 11)
Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified None. by OSHA [M-PER Component 1]. Classified None. by NIOSH [Bicine].
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s)
for the proper handling of institutional materials/equipment associated with the use of this product.
No specific hazard.
Classification Not controlled under dsd (Europe).
United States
Europe
Continued on Next Page
M-PER Mammalian Protein Extraction
Reagent
Page: 2/6
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a
collar, tie, belt or waistband.
Skin Contact
Ingestion
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. Get medical attention if irritation occurs.
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water
may be used.
Slightly hazardous in case of inhalation (lung irritant).
Not available.
Sensitization of the product: Not available.
Slightly hazardous in case of skin contact (irritant). Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Skin Contact
Slightly hazardous in case of eye contact (irritant). Eye Contact
Inhalation
Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition.
First-Aid Measures
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention if symptoms appear.
Notes to Physician Not available.
Not available. Protection of first-aiders
Ingestion
Effects and symptoms
Inhalation
Eye Contact
Section 4. First Aid Measures
Notice to Reader Get immediate medical attention.
Hazardous thermal (de)composition
products
Not available.
May be combustible at high temperature.
Not available.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Not considered to be flammable.
Section 5. Fire Fighting Measures
Flammability of the Product
Flash Points
Fire Hazards in Presence of Various
Substances
Fire Fighting Media
and Instructions
Be sure to use an approved/certified respirator or equivalent. Protective Clothing (Fire)
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is
not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
Section 6. Accidental Release Measures
Small Spill and Leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.
Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Environmental Precautions and
Clean-up Methods
Personal precautions Safety glasses. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Avoid breathing vapors or spray mists.
Section 7. Handling and Storage
Handling
Storage
Packaging materials
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.
Continued on Next Page
M-PER Mammalian Protein Extraction
Reagent
Page: 3/6
Suitable / Not suitable Use original container.
1) M-PER Component 1 Not available.
Germany
1) M-PER Component 1 Not available.
Netherlands
1) M-PER Component 1 Not available.
France
1) M-PER Component 1 Not available.
Norway
1) M-PER Component 1 Not available.
Denmark
1) M-PER Component 1 Not available.
Sweden
United States
Ingredient Name Occupational Exposure Limits
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
Section 8. Exposure Controls/Personal Protection
Exposure Limit Values
Personal Protection
Eyes
Body
Protective Clothing
(Pictograms)
Safety glasses.
Lab coat.
The lowest known value is 100°C (212°F) (Milli-Q Water).
Liquid.
7.6 [Basic.]
May start to solidify at -0.1°C (31.8°F) based on data for: Milli-Q Water.
The only known value is 1 (Water = 1) (Milli-Q Water).
The highest known value is 0.62 (Air = 1) (Milli-Q Water).
The highest known value is 2.3 kPa (@ 20°C) (Milli-Q Water).
Not applicable.
Odorless.
Not available.
Clear Colorless.
Boiling/Condensation Point
Melting/Freezing Point
0.36 (Milli-Q Water) compared to Butyl acetate.
Physical State and
Appearance
Molecular Weight
pH (1% Soln/Water)
Specific Gravity
Vapor Pressure
Vapor Density
Evaporation Rate
Odor
Taste
Color
Section 9. Physical and Chemical Properties
Continued on Next Page
M-PER Mammalian Protein Extraction
Reagent
Page: 4/6
See solubility in water.
Easily soluble in cold water.
Partially soluble in hot water.
Dispersion Properties
Solubility
The product is stable.
Not available.
Will not occur.
Keep away from heat and direct sunlight. (M-PER Component 1)
Section 10. Stability and Reactivity
Stability and Reactivity
Conditions to avoid
Materials to avoid
Hazardous Polymerization
Hazardous Decomposition
Products
Not available.
LD50: Not available.
LC50: Not available.
Slightly hazardous in case of eye contact (irritant), of inhalation (lung irritant).
CARCINOGENIC EFFECTS: Classified None. by OSHA [M-PER Component 1]. Classified None. by NIOSH [Bicine].
Not available.
To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated.
Not available.
Section 11. Toxicological Information
Toxicity to Animals
Chronic Effects on Humans
Other Toxic Effects on Humans
Special Remarks on Toxicity to
Animals
Special Remarks on Chronic
Effects on Humans
Special Remarks on Other Toxic
Effects on Humans
Ecotoxicity Not available.
Mobility
Germany water class
Not available.
Not available.
Not available.
Persistence/degradability
Bioaccumulative potential
VCI WGK: No products were found.
Section 12. Ecological Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Not available.
Waste Information
Waste Stream
Section 13. Disposal Considerations
Consult your local or regional authorities.
Continued on Next Page
M-PER Mammalian Protein Extraction
Reagent
Page: 5/6
Contact the supplier for all information regarding the proper transportation method for this material.
Section 14. Transport Information
U.S. Federal Regulations
Pennsylvania RTK: Strong base: (environmental hazard, generic environmental hazard)
Massachusetts RTK: Strong base
New Jersey: Strong base
-- HCS Classification
Section 15. Regulatory Information
California prop. 65: No products were found.
TSCA 8(b) inventory: Milli-Q Water; Strong base; Bicine
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: Strong base
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
State Regulations
CEPA DSL: Milli-Q Water; Strong base
CEPA NDSL: Bicine
Australia (NICNAS): Milli-Q Water; Strong base; Bicine
Germany water class: Strong base
VCI WGK: No products were found.
Korea (TCCL): Milli-Q Water; Strong base
Philippines (RA6969): Milli-Q Water; Strong base; Bicine
WHMIS (Canada) Not controlled under WHMIS (Canada).
This product is not classified according to the EU regulations. DSCL (EEC)
International Regulations
Not available. EINECS
International Lists
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Strong base
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: Strong base: immediate health hazard
SARA 313 toxic chemical notification and release reporting: No products were found.
This product is not classified according to the EU regulations.
Label Requirements
(Europe)
1
Not available.
Section 16. Other Information
References
Hazardous Material
Information System
(U.S.A.)
1
0
1
g
1
0
1
National Fire Protection
Association (U.S.A.)
Health
Specific Hazard
Reactivity
Fire Hazard
Health
Fire Hazard
Reactivity
Personal Protection
Continued on Next Page
M-PER Mammalian Protein Extraction
Reagent
Page: 6/6
Version 0.03
Date of Previous Issue No Previous
Validation
Validated by Pierce Administration on 9/2/2003. Verified by Pierce Administration.
Printed 9/2/2003.
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution.
Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
History of Document Changes Any information changes since last document version are marked with a triangle symbol.
Irritating to respiratory system. Full text of R-Phrases
referenced under headings 2 and 3:
Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications.