INTERNET e-mail:
EMERGENCY TELEPHONE NO. 1-800-632-5227
® BioLabs
NEW ENGLAND
Inc.
New England Biolabs
240 County Road
Ipswich MA 01938 REVISION DATE: MAY, 2008
Fusion Protein
CAS No.: 56-81-5
MATERIAL SAFETY DATA SHEET
info@neb.com
1-978-927-5054 OTHER INFORMATION CALLS
FAX 1-978-921-1350
SECTION 6–FIRE FIGHTING MEASURES
Special Firefighting Procedures: Wear self contained breathing
apparatus and protective clothing to prevent contact with skin and eyes.
Extinguishing Media:
Carbon Dioxide, Dry Chemical powder or appropriate foam
Unusual Fire and Explosions Hazard (s):
Emits toxic toxic fumes under fire conditions. Water Spray
Prevent contact with skin and eyes.
SECTION 4–HAZARDOUS IDENTIFICATION
LABEL PRECAUTIONARY STATEMENTS:
Avoid contact by inhalation, skin and ingestion.
CAUTION
Kidney
Hygroscopic
Target Organ (S)
MF: C3H803 EC No.: 200-289-5
SYNONYMS: CITIFLOUR AF 2 * GLYCERIN * GLYCERIN, ANHYDROUS * GLYCERINE * GLYCERIN MIST (ACGIH, OSHA) * GLYCERIN,
SYNTHETIC * GLYCERITOL GLYCYL ALCOHOL * CLYZERIN, WASSERFREI (GERMAN) * GROCOLENE * OSMOGLYN * 1,2,3-
PROPANETRIOL * STAR * SYNTHETIC GLYCERIN * TECHNICAL GLYCERINE * TRIHYDROXYPROPANE * 1,2,3-
TRIHYDROXYPROPANE.
CHEMICAL NAME: GLYCEROL
1. Glycerol 50% Cas. #56-81-5
2. Sodium Chloride 50% Cas. #7647-14-5
3. Tris-HCl < 1% Cas. #77-86-1
4. BME < 1% Cas. #60-24-2
5. Sodium Azide < 1% Cas. #26628-22-8
SECTION 5 –FIRST AID MEASURES
ORAL EXPOSURE: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
DERMAL EXPOSURE: In case of contact, immediately wash skin with soap and copious amounts of water.
Remove clothing and call a physician.
EYE EXPOSURE: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Assure adequate flushing by separating the eyelids with fingers. Call a physician.
INHALATION EXPOSURE: If inhaled, remove to fresh air. If breathing is difficult, call a physician.
SECTION 2 –CHEMICAL INFORMATION
#E8051S
SECTION 3–COMPOSITION/ INFORMATION ON INGREDIENT
Chemicals
? Product Name: MBP2*-paramyosin- Sal
SECTION 1 –CHEMICAL INFORMATION
Page 2 (Glycerol)
SECTION 9–EXPOSURE CONTROLS /PPE
SECTION 11 – STABILITY AND REACTIVITY
Stability: Stable
Materials to Avoid:
Strong oxidizing agents, strong bases. Hazardous Decomposition Products: Will not occur.
PROTECT FROM HEAT
Hazardous Decomposition Products:
Carbon Monoxide, Carbon Dioxide
SECTION 10– PHYSICAL AND CHEMICAL PROPERTIES
Melting Point: 20° C
Flash Point: > 392 F, > 200° C
Boiling Point: 182° C
Physical Properties: Explosion Limits in Air:
Specific Gravity: 1.262
Solubility: Water -Z26130
PH: 5.5–8.0
Vapor Density: 3.1 G/L
Vapor Pressure: < 1 MMHG @ 20°C
Lower: 0.9%
SECTION 8 – HANDLING AND STORAGE
Refer to Section 8
IRRITATION DATA:
SKN-RBT 5OO MG/24H MLD
EYE-RBT 126 MG MLD
85JCAE -, 207, 1986
BIOFX* 9-4/970
85JCAE -, 207, 1986 EYE-RBT 5OO MG/24H MLD
To the best of our knowledge, the properties have not yet been thoroughly investigated.
SECTION 12–TOXICOLOGICAL INFORMATION
RTECS #:MA8050000
Route of Exposure:
Eye Contact:
May cause eye irritation May cause skin irritation
Skin Contact Multiple Routes
May be harmful by inhalation, ingestion, or skin absorption
Chronic Effects: Target Organs, Kidney
Materials may be irritating to mucous membranes and upper respiratory tract.
GLYCEROL
SECTION 7 – ACCIDENTAL RELEASE MEASURES
PROCEDURE(S) OF PERSONAL PRECAUTION(S):
Wear self-contained breathing apparatus, chemical safety goggles,
Wear disposable coveralls and discard them after use.
rubber boots, and chemical resistant gloves.
Ventilate area and wash spill site after material pickup is complete.
METHODS FOR CLEANING UP:
Absorb on sand or vermiculite and place in a closed
container for disposal.
ORL-RAT LD5O: 12600 MG/KG
IHL-RAT LC5O: > 570 MG/M3/1H
TOXICITY DATA:
SCU-RAT LD5O: 100 MG/KG
IVN-RAT LD5O: 5566 MG/KG
ORL-MUS LD50: 4090 MG/KG
IPR-MUS LD50: 8700 MG/KG
IPR-RAT LD5O: 4420 MG/KG
FEPRA7 4, 142, 1945
RCOCB8 56, 125,1987
ARZNAD 26,1581,1976
NIIRDN 6, 215, 1982
FRZKAP (6), 56, 1977
ARZNAD 28,1579,1978
BIOFX* 9-4/970
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protective Equipment:
Respiratory
NIOSH/MSHA-approved respirator.
Hand:
Compatible chemical-resistant gloves.
Eye:
Compatible safety goggles.
AVOID INHALATION
KEEP TIGHTLY CLOSED
STORE IN A COOL DRY PLACE
FREEZE.
STORE AT –20°C
General Hygiene Measures:
Wash thoroughly after handling.
Wash contaminated clothing before use.
Data not yet available
SECTION 13–ECOLOGICAL INFORMATION
Page 3 (Glycerol)
The above information is believed to be correct but
does not purport to be all inclusive and shall be
used only as a guide.
New England Biolabs shall not be held liable
for any damage resulting from handling or
from contact with the above product.
SECTION 17– OTHER INFORMATION
SECTION 14–DISPOSAL CONSIDERATIONS
Contact a licensed professional waste disposal service to dispose of this material.
Observe all federal state and local environmental regulations.
Dissolve or mix the material with a combustable solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
SECTION 15– TRANSPORT INFORMATION
Contact New England Biolabs, Inc. Company for Transportation Information.
(RTECS) data is presented here. See actual entry in RTECS
TARGET ORGAN DATA:
Gastrointestinal (nausea or vomiting)
Behavioral (headache)
Kidney, ureter, bladder (changes in tubules)
Kidney, ureter, bladder (changes in urine composition)
Paternal effects (spermatogenesis)
Paternal effects (testes, epididymis, sperm duct)
Effects on fertility (post-implantation mortality)
Effects on fertility (male ferility index)
Only selected registry of toxic effects of chemical substance
SCU-MUS LD5O: 91 MG/KG
IVN-MUS LD5O: 4250 MG/KG
ORL-RBT LD5O: 27 GM/KG
SKN-RBT LD5O: >10 GM/KG
IVN-RBT LD5O: 53 GM/KG
ORL-GPG LD5O: 7750 MG/KG
NIIRDN 6, 215, 1982
NIIRDN 6, 215, 1982
BIOFX* 9-4/970
JAPMA8 39, 583, 1950
JIHTAB 23, 259, 1941
DMDJAP 31, 276,1959
OSHA PEL (GEN INDU): 8H TWA 15 MG/M3, TOTAL DUST
OSHA PEL (GEN INDU): 8H TWA 5 MG/M3, RESPIRABLE FRACTION
Reviews, standards and Regulations:
ACGIH TLV-TWA 10 MG/M3 DTLVS* TLV/BEI, 1999
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTER FEREAC 54, 7740, 1989.
MSHA STANDARD: NUISANCE PARTICULATES (MIST)
DTLWS* 3, 20, 1973
CFRGBR 29, 1910.1000, 1994
CFRGBR 29, 1910.1000, 1994
OSHA PEL (CONSTRUC): 8H TWA 15 MG/M3, TOTAL DUST
CFRGBR 29, 1926.55, 1994
OSHA PEL (CONSTRUC): 8H TWA 5 MG/M3, RESPIRABLE FRACTION
CFRGBR 29, 1926.55, 1994
OSHA PEL (SHIPYARD): 8H TWA 15 MG/M3, TOTAL DUST
CFRGBR 29, 1915.1000, 1993
OSHA PEL (SHIPYARD): 8H TWA 5 MG/M3, RESPIRABLE FRACTION
CFRGBR 29, 1915.1000, 1993
NOHS 1983: HZD 35085; NIS 310; TNF 67054; NOS 215;
TNE 2135546; TFE 1346631
OEL -Australia: TWA 10 MG/M3, JAN 1993
OEL -Belgium: TWA 10 MG/M3, JAN 1993
OEL -Finland: TWA 20 MG/M3, JAN 1999
OEL -France: VME 10 MG/M3, JAN 1999
OEL -The Netherlands: MAC-TGG 10 MG/M3, Jan 1999
OEL -United Kindgom: TWA 10 MG/M3, MIST Sept 2000
OEL in Argentina, Bulgaria, Colombia, Jordan, Korea Check ACC
NOHS 1974: HZD 35085; NIS 358; TNF 86657; NOS 198;
TNE 1085329
EPA TSCA SECTION 8 (B) Chemical Inventory
EPA TSCA SECTION 8 (D) Unpublished Health/Safety Studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE,
Jan. 2001
OEL=MAK
SECTION 16– REGULATORY INFORMATION