MicroScan® Yeast Turbidity Standard B1015-18 Diagnostic agents. Material Safety Data Sheet Product name Material uses Manufactured/supplied Code In case of emergency Product and company identification MicroScan® Yeast Turbidity Standard : : : : : 1 . Product type : Liquid. Siemens Healthcare Diagnostics Inc. 1717 Deerfield Road Deerfield, IL 60015-0778 1-847-267-5300 Siemens Healthcare Diagnostics Ltd. 1200 Courtneypark Drive East Mississauga, Ontario, Canada L5T-1P2 (905) 564-7333 (800) 264-0083 Transportation: (800) 424-9300 (CHEMTREC) Medical: (800) 228-5635 ext. 284 (Prosar) MSDS no. SAMS0015 Emergency overview Hazards identification Potential acute health effects No known significant effects or critical hazards. No known significant effects or critical hazards. Harmful if swallowed. Harmful in contact with skin. Eyes Skin Inhalation Ingestion Physical state Liquid. See toxicological information (section 11) CAUTION! MAY BE HARMFUL IF ABSORBED THROUGH SKIN OR IF SWALLOWED. May be harmful if absorbed through skin or if swallowed. Do not ingest. Do not get in eyes. Avoid breathing vapor or mist. Avoid contact with skin and clothing. Wash thoroughly after handling. : : : : : : OSHA/HCS status : OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). 2 . Potential chronic health effects Carcinogenicity : No known significant effects or critical hazards. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Chronic effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. Over-exposure signs/symptoms Ingestion : No specific data. Skin : No specific data. Eyes : No specific data. Inhalation : No specific data. Not available. 1/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard sodium azide 26628-22-8 0.1978 Composition/information on ingredients Name CAS number % United States 3 . There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section. Move exposed person to fresh air. Loosen tight clothing such as a collar, tie, belt or waistband. Never give anything by mouth to an unconscious person. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention if irritation occurs. Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms occur. First aid measures Eye contact Skin contact Inhalation Ingestion : : : : 4 . Fire-fighting measures Extinguishing media Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Aqueous solutions are non-flammable. Special protective equipment for fire-fighters Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. : 5 . Special exposure hazards : None known. Not suitable : Hazardous combustion products : No specific data. Flammability of the product : In case of fire, use water spray (fog), foam or dry chemical. No action shall be taken involving any personal risk or without suitable training. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Put on appropriate personal protective equipment (see section 8). Environmental precautions Accidental release measures : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Personal precautions : 6 . Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Small spill : Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. Handling and storage Handling : 7 . 2/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard Handling and storage 7 . Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. Storage : sodium azide ACGIH TLV (United States, 1/2007). Notes: as sodium azide C: 0.29 mg/m³, (as sodium azide) NIOSH REL (United States, 12/2001). Absorbed through skin. Notes: NAN3 OSHA PEL 1989 (United States, 3/1989). Absorbed through skin. Notes: as NaN3 ACGIH TLV (United States, 1/2007). Notes: as hydrazoic acid vapor C: 0.11 ppm, (as hydrazoic acid vapor) Form: Vapor NIOSH REL (United States, 12/2001). Absorbed through skin. Notes: NAN3 OSHA PEL 1989 (United States, 3/1989). Absorbed through skin. Notes: as NaN3 NIOSH REL (United States, 12/2001). Absorbed through skin. Notes: NAN3 CEIL: 0.3 mg/m³, (NAN3) OSHA PEL 1989 (United States, 3/1989). Absorbed through skin. Notes: as NaN3 NIOSH REL (United States, 12/2001). Absorbed through skin. Notes: NAN3 CEIL: 0.1 ppm, (as HN3) OSHA PEL 1989 (United States, 3/1989). Absorbed through skin. Notes: as NaN3 CEIL: 0.1 ppm, (as HN3) NIOSH REL (United States, 12/2001). Absorbed through skin. Notes: NAN3 OSHA PEL 1989 (United States, 3/1989). Absorbed through skin. Notes: as NaN3 CEIL: 0.3 mg/m³, (as NaN3) Exposure controls/personal protection Product name Exposure limits Consult local authorities for acceptable exposure limits. United States 8 . 3/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard Exposure controls/personal protection 8 . Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists or dusts. Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Personal protection Eyes Skin Respiratory : : : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Hands : Engineering measures : No special ventilation requirements. Good general ventilation should be sufficient to control worker exposure to airborne contaminants. If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. Recommended monitoring procedures : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Environmental exposure controls : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels. SODIUM AZIDE, in the quantity present and as this product is normally used, is not likely to have adverse human health effects. Liquid. Easily soluble in the following materials: cold water. Physical and chemical properties Physical state Solubility : : 9 . The product is stable. No specific data. Under normal conditions of storage and use, hazardous polymerization will not occur. Under normal conditions of storage and use, hazardous decomposition products should not be produced. No specific data. Stability and reactivity Stability Conditions to avoid Materials to avoid Hazardous decomposition products Hazardous polymerization : : : : : 10 . Not available. 4/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard Toxicological information United States Canada 11 . Acute toxicity sodium azide LD50 Dermal Rat 50 mg/kg - LD50 Dermal Rabbit 20 mg/kg - LD50 Intratracheal Rat 47.5 mg/kg - LD50 Intratracheal Rat 47500 ug/kg - LD50 Oral Rat 27 mg/kg - LD50 Subcutaneous Rat 45100 ug/kg - LD50 Subcutaneous Rat 45 mg/kg - LDLo Intraperitoneal Rat 3 mg/kg - LDLo Intraperitoneal Rat 30 mg/kg - Product/ingredient name Result Species Dose Exposure Acute toxicity Not available. Chronic toxicity Not available. Carcinogenicity Not available. Mutagenicity Not available. Teratogenicity Not available. Reproductive toxicity Not available. Chronic toxicity Not available. Carcinogenicity Not available. Mutagenicity Not available. Teratogenicity Not available. Reproductive toxicity Not available. Classification sodium azide A4 - - None. - - Product/ingredient name ACGIH EPA NIOSH NTP IARC OSHA Classification sodium azide A4 - - None. - - Product/ingredient name ACGIH EPA NIOSH NTP IARC OSHA 5/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard Ecological information United States Canada Environmental effects : No known significant effects or critical hazards. 12 . Aquatic ecotoxicity sodium azide - Acute EC50 6.4 to 8.9 mg/L Fresh water Crustaceans - Water flea - Simocephalus serrulatus - LARVAE 48 hours - Acute EC50 4.2 to 6.2 mg/L Fresh water Daphnia - Water flea - Daphnia pulex - LARVAE 48 hours - Acute LC50 0.8 mg/L Fresh water Fish - Rainbow trout,donaldson trout - Oncorhynchus mykiss - 1.4 g 96 hours - Acute LC50 0.68 mg/L Fresh water Fish - Bluegill - Lepomis macrochirus - 0.6 g 96 hours - Acute LC50 5460 to 5870 ug/L Fresh water Fish - Fathead minnow - Pimephales promelas - 30 days - 18.8 mm - 0.098 g 96 hours - Acute LC50 3920 ug/L Fresh water Fish - Rainbow trout,donaldson trout - Oncorhynchus mykiss - 8.57 cm - 7.84 g 96 hours - Acute LC50 2840 ug/L Fresh water Fish - Rainbow trout,donaldson trout - Oncorhynchus mykiss - 7.87 cm - 6.07 g 96 hours - Acute LC50 2750 ug/L Fresh water Fish - Rainbow trout,donaldson trout - Oncorhynchus mykiss - 7.32 cm - 4.76 g 96 hours Product/ingredient name Test Species Result Exposure Biodegradability Not available. Aquatic ecotoxicity Not available. Biodegradability Not available. 6/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard The generation of waste should be avoided or minimized wherever possible. Empty containers or liners may retain some product residues. This material and its container must be disposed of in a safe way. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any byproducts should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Waste disposal Disposal considerations Disposal should be in accordance with applicable regional, national and local laws and regulations. : 13 . Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Sodium azide may react with lead or copper plumbing to form highly explosive metal azides. Transport information - - DOT Classification TDG Classification - - - Not regulated. - - ADR/RID Class - - - IMDG Class - - - - Not regulated. IATA-DGR Class - Regulatory information UN number Proper shipping name Classes PG* Label Additional information - Not regulated. Not regulated. - - - Not regulated. - Mexico Classification Not regulated. - - - - 14 . PG* : Packing group OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). HCS Classification Regulatory information U.S. Federal regulations United States inventory (TSCA 8b): Not determined. TSCA 8(d) H and S data reporting: potassium dihydrogenorthophosphate Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: sodium phosphate, dibasic Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. : : United States 15 . 7/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard Regulatory information 15 . Connecticut Carcinogen Reporting: None of the components are listed. Connecticut Hazardous Material Survey: None of the components are listed. Florida substances: None of the components are listed. Illinois Chemical Safety Act: None of the components are listed. Illinois Toxic Substances Disclosure to Employee Act: None of the components are listed. Louisiana Reporting: None of the components are listed. Louisiana Spill: None of the components are listed. Massachusetts Spill: None of the components are listed. Massachusetts Substances: None of the components are listed. Michigan Critical Material: None of the components are listed. Minnesota Hazardous Substances: None of the components are listed. New Jersey Hazardous Substances: None of the components are listed. New Jersey Spill: None of the components are listed. New Jersey Toxic Catastrophe Prevention Act: None of the components are listed. New York Acutely Hazardous Substances: None of the components are listed. New York Toxic Chemical Release Reporting: None of the components are listed. Pennsylvania RTK Hazardous Substances: None of the components are listed. Rhode Island Hazardous Substances: None of the components are listed. State regulations CEPA Toxic substances: None of the components are listed. Canadian ARET: None of the components are listed. Canadian NPRI: None of the components are listed. Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. WHMIS (Canada) Not controlled under WHMIS (Canada). : : Canada MicroScan® Yeast Turbidity Standard No. No. No. No. Ingredient name Cancer Reproductive No significant risk level Maximum acceptable dosage level This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all the information required by the Controlled Products Regulations. Canadian lists : California Prop. 65 United States inventory (TSCA 8b) : Not determined. Canada inventory : Not determined. Other information 16 . International regulations R22- Harmful if swallowed. Risk phrases EU regulations : Hazard symbol or symbols : Harmful 8/9 B1015-18 8/13/2008. MicroScan® Yeast Turbidity Standard Other information 16 . Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Date of printing Date of issue Version 8/13/2008. 8/13/2008. 1.1 : : : Australia inventory (AICS): Not determined. China inventory (IECSC): Not determined. Japan inventory (ENCS): Not determined. Japan inventory (ISHL): Not determined. Korea inventory (KECI): Not determined. New Zealand Inventory of Chemicals (NZIoC): Not determined. Philippines inventory (PICCS): Not determined. International lists : 9/9 B1015-18 8/13/2008.