n-BUTYRIC ACID n-BUTYRIC ACID MSDS Number: B7612 --- Effective Date: 11/17/99 1. Product Identification Synonyms: Butanoic acid; Ethylacetic Acid, Propylformic Acid CAS No.: 107-92-6 Molecular Weight: 88.11 Chemical Formula: CH3CH2CH2COOH 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------- --------- Butyric Acid 107-92-6 100% Yes 3. Hazards Identification Emergency Overview -------------------------- DANGER! CORROSIVE. CAUSES BURNS TO SKIN AND EYES. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MAY CAUSE RESPIRATORY TRACT IRRITATION. COMBUSTIBLE LIQUID AND VAPOR. Potential Health Effects ---------------------------------- Depending on contact areas and exposure, n-butyric acid can act as an irritant or as a corrosive. Inhalation: Vapors irritate the respiratory tract. Symptoms include sore throat, coughing and shortness of breath. Ingestion: Corrosive. May cause tissue damage. Skin Contact: Corrosive. Cause skin burns. May be absorbed through the skin. Eye Contact: Corrosive. Vapors irritate the eyes. Splashes may cause eye damage. Chronic Exposure: No information found. Aggravation of Pre-existing Conditions: No information found. 4. First Aid Measures Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician. Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention. Skin Contact: Remove any contaminated clothing and shoes. Wash skin with soap or mild detergent and water for at least 15 minutes. Get medical attention if irritation develops or persists. Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately. 5. Fire Fighting Measures Fire: Flash point: 72C (162F) CC Autoignition temperature: 440C (824F) Flammable limits in air % by volume: lel: 2; uel: 10 Combustible Liquid. Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. 6. Accidental Release Measures Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802. 7. Handling and Storage Protect against physical damage. Outside or detached storage is preferred. Inside storage should be in a standard flammable liquids storage room or cabinet. Separate from oxidizing materials. Storage and use areas should be No Smoking areas. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: None established. Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres. Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area. 9. Physical and Chemical Properties Appearance: Clear, colorless liquid. Odor: Unpleasant rancid odor. Solubility: Completely soluble in water. Density: 0.96 pH: No information found. % Volatiles by volume @ 21C (70F): No information found. Boiling Point: 162C (324F) Melting Point: -7 - -5C (19 - 23F) Vapor Density (Air=1): 3.0 Vapor Pressure (mm Hg): 0.43 @ 20C (68F) Evaporation Rate (BuAc=1): No information found. 10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition. Hazardous Polymerization: Will not occur. Incompatibilities: Aluminum or other light metals, chromium trioxide, and oxidizing materials. The solution in water is acid, reacts with bases, and is corrosive. Conditions to Avoid: Heat, flame, other sources of ignition. 11. Toxicological Information Investigated as a mutagen. Oral rat LD50: 2000 mg/kg Skin, rabbit LD50:530 uL/Kg; Irritation data, standard Draize test, Eye, rabbit, open: 250 ug - Severe --------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- Butyric Acid (107-92-6) No No None 12. Ecological Information Environmental Fate: When released into the soil, this material is not expected to leach into groundwater. When released into the soil, this material is not expected to evaporate significantly. When released into water, this material is expected to readily biodegrade. When released into water, this material is not expected to evaporate significantly. When released into the water, this material is expected to have a half-life of greater than 30 days. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-life between 1 and 10 days. When released into the air, this material may be removed from the atmosphere to a moderate extent by wet deposition. This material has a log octanol-water partition coefficient of less than 3.0. This material is not expected to significantly bioaccumulate. Environmental Toxicity: No information found. 13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements. 14. Transport Information Domestic (Land, D.O.T.) ----------------------- Proper Shipping Name: BUTYRIC ACID Hazard Class: 8 UN/NA: UN2820 Packing Group: III Information reported for product/size: 500ML International (Water, I.M.O.) ----------------------------- Proper Shipping Name: NORMAL-BUTYRIC ACID Hazard Class: 8 UN/NA: UN2820 Packing Group: III Information reported for product/size: 500ML International (Air, I.C.A.O.) ----------------------------- Proper Shipping Name: NORMAL-BUTYRIC ACID Hazard Class: 8 UN/NA: UN2820 Packing Group: III Information reported for product/size: 500ML 15. Regulatory Information --------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- Butyric Acid (107-92-6) Yes Yes Yes Yes --------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- Butyric Acid (107-92-6) Yes Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- Butyric Acid (107-92-6) No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCA- Ingredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ Butyric Acid (107-92-6) 5000 No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: Yes Chronic: No Fire: Yes Pressure: No Reactivity: No (Pure / Liquid) Australian Hazchem Code: 2R Poison Schedule: No information found. WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR. 16. Other Information NFPA Ratings: Health: 2 Flammability: 2 Reactivity: 0 Label Hazard Warning: DANGER! CORROSIVE. CAUSES BURNS TO SKIN AND EYES. HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. MAY CAUSE RESPIRATORY TRACT IRRITATION. COMBUSTIBLE LIQUID AND VAPOR. Label Precautions: Keep away from heat and flame. Avoid breathing vapor. Do not get in eyes, on skin, or on clothing. Keep container closed. Use with adequate ventilation. Wash thoroughly after handling. Label First Aid: In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Call a physician. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, call a physician immediately. Product Use: Laboratory Reagent. Revision Information: No changes. Disclaimer: ************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION. ************************************************************************************************ Prepared by: Environmental Health & Safety Phone Number: (314) 654-1600 (U.S.A.)