Material Safety Data Sheet **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION **** MSDS Name: n-Ethylmaleimide Catalog Numbers: O2829 25, O2829-25, O282925 Synonyms: 1-Ethyl-1H-Pyrrole-2,5-Dione; NEM; Cryptopyrrole. Company Identification: Fisher Scientific 1 Reagent Lane Fairlawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887 **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 128-53-0 |Maleic acid n-ethylimide | 100 | 204-892-4 | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: T Risk Phrases: 25 34 **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW Toxic if swallowed. Causes burns.The toxicological properties of this material have not been fully investigated.Lachrymator.Corrosive. Potential Health Effects Eye: Causes eye burns. Lachrymator. May cause corneal edema and inflammation. Skin: Causes skin burns. Ingestion: May cause severe irritation of the digestive tract. Inhalation: May cause severe respiratory tract irritation. Chronic: No information found. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Skin: Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing Media: Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. **** SECTION 7 - HANDLING and STORAGE **** Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES **** Physical State: Solid Appearance: white Odor: strong odor - pungent odor pH: Not available. Vapor Pressure: Negligible. Vapor Density: 4.3 (air=1) Evaporation Rate: Negligible. Viscosity: Not available. Boiling Point: 210 deg C Freezing/Melting Point: 45 deg C Autoignition Temperature: Not available. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility: Soluble in water. Specific Gravity/Density: Not available. Molecular Formula: C6H7NO2 Molecular Weight: 125.0545 **** SECTION 10 - STABILITY AND REACTIVITY **** Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: High temperatures, incompatible materials, dust generation. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong bases Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. **** SECTION 11 - TOXICOLOGICAL INFORMATION **** RTECS#: CAS# 128-53-0: UX9625000 LD50/LC50: CAS# 128-53-0: Dermal, guinea pig: LD50 = 500 mg/kg; Oral, mouse: LD50 = 25 mg/kg; Oral, rat: LD50 = 25 mg/kg. Carcinogenicity: Maleic acid n-ethylimide - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available. Mutagenicity: DNA Inhibition: hamster lung 750nmol/L; human cell types 6umol/L; mouse cell types 300umol/L; rat liver 2umol. Other Studies: None. **** SECTION 12 - ECOLOGICAL INFORMATION **** Other No information available. **** SECTION 13 - DISPOSAL CONSIDERATIONS **** Dispose of in a manner consistent with federal, state, and local regulations. **** SECTION 14 - TRANSPORT INFORMATION **** US DOT Shipping Name: **SMALL QTY EXCEPTION SEE 49CFR 173.4** Hazard Class: 110 UN Number: UN0001 Packing Group: Canadian TDG Shipping Name: POISONOUS SOLID NOS (MALONIC ESTERS) Hazard Class: 6.1(9.2) UN Number: UN2811 **** SECTION 15 - REGULATORY INFORMATION **** US FEDERAL TSCA CAS# 128-53-0 is listed on the TSCA inventory. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE Maleic acid n-ethylimide is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 25 Toxic if swallowed. R 34 Causes burns. Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 128-53-0: 3 United Kingdom Occupational Exposure Limits Canada CAS# 128-53-0 is listed on Canada's DSL List. CAS# 128-53-0 is listed on Canada's Ingredient Disclosure List. Exposure Limits **** SECTION 16 - ADDITIONAL INFORMATION **** MSDS Creation Date: 9/23/1998 Revision #1 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------