Page 1/6
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 22.06.2007 Revision: 22.06.2007
DR
1 Identification of substance:
· Product details:
· Trade name: NEFA C Color Reagent A
· Application of the substance / the preparation: In vitro diagnostics
· Manufacturer / Supplier:
For Europe:
Wako Chemicals GmbH Phone: ++49(0)2131 - 311-0
Nissanstrasse 2 Fax: ++49(0)2131 - 311-100
D-41468 Neuss
· E-mail address of the competent person responsible for the Safety Data Sheet: info@csb-online.de
· Informing department: Sales
· Emergency information: As above or next toxicological information centre
2 Hazards identification
· Hazard designation:
T Toxic
· Information pertaining to particular dangers for man and environment
R 25 Toxic if swallowed.
R 52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
· Classification system
The product has to be labelled due to the calculation procedure of the "General Classification guideline for
preparations of the EU" in the latest valid version.
3 Composition/information on ingredients
· Chemical characterization
· Description: Mixture of the substances listed below with harmless products.
· Dangerous components:
CAS: 57-50-1
EINECS: 200-334-9
sucrose 10-25%
CAS: 83-07-8
EINECS: 201-452-3
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
Xn; R 22
< 2.5%
CAS: 26628-22-8
EINECS: 247-852-1
Index Number: 011-004-00-7
Sodium azide
T+, N; R 28-32-50/53
< 2.5%
· Additional information For the wording of the listed risk phrases refer to section 16.
4 First aid measures
· General information
Immediately remove any clothing contaminated by the product.
Personal protection for the person providing first aid.
· After inhalation
Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor.
In case of unconsciousness bring patient into stable side position for transport.
· After skin contact
Instantly wash with water and soap and rinse thoroughly.
Consult a doctor for safety reasons.
(Contd. on page 2)
GB
Page 2/6
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 22.06.2007 Revision: 22.06.2007
Trade name: NEFA C Color Reagent A
(Contd. of page 1)
DR
· After eye contact Rinse opened eye for several minutes under running water. Then consult doctor.
· After swallowing
Rinse out mouth and then drink plenty of water.
Call a doctor immediately.
5 Fire fighting measures
· Suitable extinguishing agents
CO 2, extinguishing powder or water spray/fog. Fight larger fires with water spray/fog or alcohol-resistant
foam.
· For safety reasons unsuitable extinguishing agents none
· Special hazards caused by the material, its products of combustion or flue gases:
Nitrogen oxides (NOx)
Oxides of phosphorus (PxOy)
Sulphur oxides (SOx)
Carbon monoxide (CO) and Carbon dioxide (CO 2)
· Protective equipment: Put on breathing apparatus.
· Additional information Collect contaminated fire fighting water separately. It must not enter drains.
6 Accidental release measures
· Person-related safety precautions:
Ensure adequate ventilation.
Keep people at a distance and stay on the windward side.
Avoid causing dust.
Avoid breathing dust.
Avoid skin and eye contact.
· Measures for environmental protection: Do not allow product to reach sewage system or water bodies.
· Measures for cleaning/collecting:
Collect mechanically.
Dispose of contaminated material as waste according to item 13.
7 Handling and storage
· Handling
· Information for safe handling:
Ensure good ventilation/exhaustion at the workplace.
Keep away from heat and direct sunlight.
Prevent formation of dust.
Do not breathe dust.
Avoid skin and eye contact.
Make sure that all applicable workplace limits are observed.
· Information about protection against explosions and fires:
Protect from heat.
Do not mix with heavy metals and their salts.
· Storage
· Requirements to be met by storerooms and containers:
Observe all local and national regulations for storage of water polluting products.
· Information about storage in one common storage facility:
Do not store together with oxidizing and acidic materials as well as heavy-metal compounds.
· Further information about storage conditions:
Store in cool, dry conditions in well sealed containers.
Protect from heat and direct sunlight.
Store container in a well ventilated position.
(Contd. on page 3)
GB
Page 3/6
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 22.06.2007 Revision: 22.06.2007
Trade name: NEFA C Color Reagent A
(Contd. of page 2)
DR
Storage temperature 2 - 10 °C
8 Exposure controls and personal protection
· Additional information about design of technical systems: No further data; see item 7.
· Components with critical values that require monitoring at the workplace:
57-50-1 sucrose
OES (Great Britain) Short-term value: 20 mg/m³
Long-term value: 10 mg/m³
26628-22-8 Sodium azide
OES (Great Britain)
TLV (European Union)
Short-term value: 0.3 mg/m³
Long-term value: 0.1 mg/m³
as NaN3, New, IOELV, Sk
Short-term value: 0.3 mg/m³
Long-term value: 0.1 mg/m³
Skin
· Additional information: The lists that were valid during the compilation were used as basis.
· Personal protective equipment
· General protective and hygienic measures
Keep away from foodstuffs, beverages and food.
Instantly remove any contaminated garments.
Store protective clothing separately.
Do not inhale dust / smoke / mist.
Avoid contact with the eyes and skin.
Wash hands during breaks and at the end of the work.
· Breathing equipment:
If all workplace limits are observed and good ventilation is ensured,
no special precautions nessecary.
· Protection of hands:
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/
the chemical mixture.
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality
and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the
resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the
application.
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be
observed.
· Eye protection: Safety glasses
· Body protection: Protective work clothing
9 Physical and chemical properties:
· General Information
Form: Powder
Colour: white
Smell: odourless
· Change in condition
Melting point/Melting range: not determined
Boiling point/Boiling range: not determined
(Contd. on page 4)
GB
Page 4/6
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 22.06.2007 Revision: 22.06.2007
Trade name: NEFA C Color Reagent A
(Contd. of page 3)
DR
· Flash point: not applicable
· Self-inflammability: Product is not selfigniting.
· Danger of explosion: Product is not explosive.
· Density not determined
· Solubility in / Miscibility with
Water: soluble
10 Stability and reactivity
· Thermal decomposition / conditions to be avoided: Heat
· Materials to be avoided:
Strong oxidizing agents
Strong acids
Heavy metals
· Dangerous reactions Forms very sensitive explosive metallic compounds.
· Dangerous products of decomposition:
Nitrogen oxides (NOx)
Phosphorus oxides (e.g. P 2O 5)
Sulphur oxides (SOx)
Carbon monoxide (CO) and Carbon dioxide (CO 2)
11 Toxicological information
· Acute toxicity:
· LD/LC50 values that are relevant for classification:
26628-22-8 Sodium azide
Oral LD50 27 mg/kg (rat)
Dermal LD50 20 mg/kg (rabbit)
· Primary irritant effect:
· on the skin: Slightly irritating
· on the eye: Weak irritating effect
· Sensitization: No sensitizing effect known.
· Additional toxicological information:
Danger by skin resorption.
The product shows the following dangers according to the calculation method of the General EC
Classification Guidelines for Preparations as issued in the latest version:
Toxic
12 Ecological information:
· Ecotoxical effects:
· Aquatic toxicity:
26628-22-8 Sodium azide
LC50/96 h 0.7 mg/l (bluegill (lepomis macrochirus))
· General notes:
Water danger class 3 (Self-assessment): extremely hazardous for water.
Harmful to aquatic organisms
GB
(Contd. on page 5)
Page 5/6
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 22.06.2007 Revision: 22.06.2007
Trade name: NEFA C Color Reagent A
(Contd. of page 4)
DR
13 Disposal considerations
· Product:
· Recommendation Disposal must be made according to official regulations.
· European waste catalogue
Waste disposal key numbers from EWC have to be assigned depending on origin and processing.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleaning agent: Water, if necessary with cleaning agent.
14 Transport information
· Land transport ADR/RID (cross-border):
· ADR/RID Class: -
· Maritime transport IMDG/GGVSea:
· IMDG/GGVSea Class: -
· Air transport ICAO-TI and IATA-DGR:
· ICAO/IATA Class: -
· Transport/Additional information: Not dangerous according to the above specifications.
15 Regulatory information
· Designation according to EC guidelines:
The product has been classified/labelled in accordance with EC Directives / relevant national laws.
· Code letter and hazard designation of product:
T Toxic
· Hazard-determining components of labelling:
Sodium azide
· Risk phrases:
25 Toxic if swallowed.
52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
· Safety phrases:
45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
61 Avoid release to the environment. Refer to special instructions/safety data sheets.
· National regulations
· Decree to be applied in case of technical fault:
Quantity limits according to "EC Seveso directive" should be observed.
· Water hazard class: Water danger class 3 (Self-assessment): extremely hazardous for water.
16 Other information:
These data are based on our present knowledge. However, they shall not constitute a guarantee for any
specific product features and shall not establish a legally valid contractual relationship.
· Relevant R-phrases
The(se) R-phrase(s) are those of the ingredient(s) and do(es) NOT represent the classification of the
preparation.
22 Harmful if swallowed.
(Contd. on page 6)
GB
Page 6/6
Safety Data Sheet
according to 1907/2006/EC, Article 31
Printing date 22.06.2007 Revision: 22.06.2007
Trade name: NEFA C Color Reagent A
(Contd. of page 5)
DR
28 Very toxic if swallowed.
32 Contact with acids liberates very toxic gas.
50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
· Department issuing MSDS:
C.S.B. GmbH Phone: +49 - 2151 - 652086-0
Oberstraße 10 Fax: +49 - 2151 - 652086-9
D-47829 Krefeld
Germany
GB