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MSDS Safety Information 
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NAME: NEGATIVE CONTROL MAB

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SAFETY DATA SHEET
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE
COMPANY/UNDERTAKING
VENTANA MEDICAL SYSTEMS, INC.
1910 E. Innovation Park Drive
Tucson, Arizona 85755
U.S.A.
+1 (520) 887-2155
(800) 227-2155 (U.S.)
EC REP
Roche Diagnostics GmbH Roche Diagnostics Australia Pty. Ltd
Sandhofer Strasse 116 31 Victoria Avenue
D-68305 Mannheim Castle Hill, NSW, 2154
Germany Australia
Phone: 61-2-9860-2329
Fax: 61-2-9860-2133
Emergency Phone Number: 61-2-9759-4301
SDS NUMBER: 00232115
SUBSTANCE: FITC anti-Biotin MAb
PRODUCT NUMBER(S): 780-2848, 800-2848
PRODUCT USE: clinical/research
CREATION DATE: Aug 30 2006
REVISION DATE: Mar 05 2009
2. HAZARDS IDENTIFICATION
NFPA RATINGS (SCALE 0-4): HEALTH=1 FIRE=0 REACTIVITY=0
EC CLASSIFICATION:
No classification assigned.
EMERGENCY OVERVIEW:
COLOUR: colourless to amber
PHYSICAL FORM: liquid
ODOUR: odourless
MAJOR HEALTH HAZARDS: No significant target effects reported.
POTENTIAL HEALTH EFFECTS:
INHALATION:
SHORT TERM EXPOSURE: irritation
LONG TERM EXPOSURE: no information on significant adverse effects
SKIN CONTACT:
SHORT TERM EXPOSURE: irritation
LONG TERM EXPOSURE: irritation
EYE CONTACT:
SHORT TERM EXPOSURE: mild irritation
LONG TERM EXPOSURE: no information on significant adverse effects
INGESTION:
SHORT TERM EXPOSURE: nausea, diarrhoea, vomiting, irregular heartbeat
LONG TERM EXPOSURE: no information on significant adverse effects
3. COMPOSITION, INFORMATION ON INGREDIENTS
COMPONENT: Non-hazardous
CAS NUMBER: Not assigned.
EC NUMBER: Not assigned.
PERCENTAGE: 60-100
EC CLASSIFICATION: No classification assigned.
COMPONENT: Sodium azide
CAS NUMBER: 26628-22-8
EC NUMBER (EINECS): 247-852-1
PERCENTAGE: <1
EC CLASSIFICATION: T+; N
RISK PHRASES: 28-32-50/53
COMPONENT: IGEPAL CA-630
CAS NUMBER: 9036-19-5
EC NUMBER: Not assigned.
PERCENTAGE: <1
EC CLASSIFICATION: Xi
RISK PHRASES: 38-41
4. FIRST AID MEASURES
INHALATION: If adverse effects occur, remove to uncontaminated area. Give artificial respiration if not
breathing. Get immediate medical attention.
SKIN CONTACT: Wash contaminated areas with soap and water. Thoroughly clean and dry contaminated
clothing before reuse. Get medical attention, if needed.
EYE CONTACT: Flush eyes with plenty of water for at least 15 minutes. Then get immediate medical
attention.
INGESTION: If a large amount is swallowed, get medical attention.
5. FIRE FIGHTING MEASURES
FIRE AND EXPLOSION HAZARDS: Negligible fire hazard.
EXTINGUISHING MEDIA: Use extinguishing agents appropriate for surrounding fire.
FIRE FIGHTING: Move container from fire area if it can be done without risk. Avoid inhalation of
material or combustion by-products.
SENSITIVITY TO MECHANICAL IMPACT: Not sensitive
SENSITIVITY TO STATIC DISCHARGE: Not sensitive
FLASH POINT: not flammable
6. ACCIDENTAL RELEASE MEASURES
WATER RELEASE:
Keep out of water supplies and drains.
OCCUPATIONAL RELEASE:
Absorb with sand or other non-combustible material. Collect spilled material in appropriate container for
disposal.
7. HANDLING AND STORAGE
STORAGE: Store and handle in accordance with all current regulations and standards. Store between 2 C
and 8 C. See original container for storage recommendations. Keep separated from incompatible substances.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
EXPOSURE LIMITS:
FITC anti-Biotin MAb:
No occupational exposure limits established.
VENTILATION: Provide adequate ventilation. Ensure compliance with applicable exposure limits.
EYE PROTECTION: Safety glasses or goggles are recommended when there is a potential for eye contact.
Provide an emergency eye wash fountain and quick drench shower in the immediate work area.
CLOTHING: Lab coat or apron.
GLOVES: Wear appropriate chemical resistant gloves.
PROTECTIVE MATERIAL TYPES: latex, vinyl
RESPIRATOR: No respirator is required under normal conditions of use.
9. PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE: liquid
COLOUR: colourless to amber
ODOUR: odourless
BOILING POINT: Not available
FREEZING POINT: Not available
VAPOUR PRESSURE: Not available
VAPOUR DENSITY: Not available
SPECIFIC GRAVITY: Not available
WATER SOLUBILITY: miscible
PH: neutral
VOLATILITY: Not available
ODOUR THRESHOLD: Not available
EVAPORATION RATE: Not available
COEFFICIENT OF WATER/OIL DISTRIBUTION: Not available
10. STABILITY AND REACTIVITY
REACTIVITY: Stable at normal temperatures and pressure.
CONDITIONS TO AVOID: None reported.
INCOMPATIBILITIES: oxidising materials
HAZARDOUS DECOMPOSITION:
Thermal decomposition products: miscellaneous decomposition products
POLYMERISATION: Will not polymerise.
11. TOXICOLOGICAL INFORMATION
Not available
12. ECOLOGICAL INFORMATION
Not available
13. DISPOSAL CONSIDERATIONS
Dispose in accordance with all applicable regulations.
14. TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION: Not regulated.
CANADIAN TRANSPORTATION OF DANGEROUS GOODS: Not regulated.
LAND TRANSPORT ADR: Not regulated.
LAND TRANSPORT RID: Not regulated.
AIR TRANSPORT IATA: Not regulated.
AIR TRANSPORT ICAO: Not regulated.
MARITIME TRANSPORT IMDG: Not regulated.
15. REGULATORY INFORMATION
U.S. REGULATIONS:
CERCLA SECTIONS 102a/103 HAZARDOUS SUBSTANCES (40 CFR 302.4):
Sodium azide: 1000 LBS RQ
Ethylene oxide: 10 LBS RQ
1,4-Dioxane: 100 LBS RQ
SARA TITLE III SECTION 302 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355 Subpart
B): Not regulated.
SARA TITLE III SECTION 304 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355 Subpart
C): Not regulated.
SARA TITLE III SARA SECTIONS 311/312 HAZARDOUS CATEGORIES (40 CFR 370 Subparts B
and C):
ACUTE: No
CHRONIC: No
FIRE: No
REACTIVE: No
SUDDEN RELEASE: No
SARA TITLE III SECTION 313 (40 CFR 372.65): Not regulated.
STATE REGULATIONS:
California Proposition 65:
Known to the state of California to cause the following:
Ethylene oxide
Cancer (Jul 01, 1987)
Female reproductive toxicity (Feb 27, 1987)
1,4-Dioxane
Cancer (Jan 01, 1988)
CANADIAN REGULATIONS:
WHMIS CLASSIFICATION: Not a Controlled Product under Canada's Workplace Hazardous Material
Information System.
EUROPEAN REGULATIONS:
EC CLASSIFICATION (CALCULATED):
No classification assigned.
16. OTHER INFORMATION
EC RISK PHRASES:
R 28 Very toxic if swallowed.
R 32 Contact with acids liberates very toxic gas.
R 38 Irritating to skin.
R 41 Risk of serious damage to eyes.
R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
environment.
Limitations: The information and recommendations set forth in this SDS are believed to be correct as
of this date. Ventana Medical Systems, Inc. makes no warranty with respect to the content of this SDS
and disclaims all liability from reliance thereon.