UPJOHN -- NEOMYCIN SULFATE ======================================================= MSDS Safety Information ======================================================= FSC: 6505 NIIN: 00-299-9527 MSDS Date: 11/12/1990 MSDS Num: BTCHY Product ID: NEOMYCIN SULFATE MFN: 01 Responsible Party Cage: GO374 Name: UPJOHN CO THE Address: 7171 PORTAGE RD City: KALAMAZOO MI 49001 Info Phone Number: 616-385-7358 Emergency Phone Number: 616-323-7555(D)/616-323-6722(24 HR) Review Ind: Y Published: Y ======================================================= Preparer Co. when other than Responsible Party Co. ======================================================= Cage: GO374 Assigned Ind: Y Name: UPJOHN CO THE Address: 7171 PORTAGE RD City: KALAMAZOO MI 49001-0199 ======================================================= Contractor Summary ======================================================= Cage: 61059 Name: CLAY PARK LABS INC Address: 1700 BATHGATE AVE City: BRONX NY 10457 Phone: 718-901-2800 Cage: 93703 Name: PHARMACIA & UPJOHN Address: 7171 PORTAGE RD City: KALAMAZOO MI 49001-0199 Phone: 616-833-5122/616-833-7555 Cage: GO374 Name: UPJOHN CO THE Address: 7171 PORTAGE RD City: KALAMAZOO MI 49001-0199 Phone: 616-323-7555 ======================================================= Item Description Information ======================================================= Item Name: NEOMYCIN SULFATE,USP ======================================================= Ingredients ======================================================= Cas: 1405-10-3 RTECS #: QP4375000 Name: NEOMYCIN SULFATE % Wt: 100 ======================================================= Health Hazards Data ======================================================= LD50 LC50 Mixture: ORAL LD50 (RAT): >4325 MG/KG Route Of Entry Inds - Inhalation: YES Skin: YES Ingestion: YES Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO Effects of Exposure: INHALATION/SKIN: MILD TO SEVERE ALLERGIC REACTION. ALLERGIC RESPONSE INCLUDING ANAPHYLAXIS. MAY CAUSE SEVERE KIDNEY TOXICITY & NEUROTOXICITY. Explanation Of Carcinogenicity: NONE Signs And Symptions Of Overexposure: ALLERGIC RESPONSE MAY INCLUDE SKIN RASH, FEVER, BRONCHOSPASM, SWELLING OF LIPS, TONGUE & FACE, ASTHMATIC BREATHING & HIVES. NEUROTOXICITY MAY INCLUDE HEARING LOSS, DIMINISHED BALANCE, NUMBNESS, SKIN T INGLING, MUSCLE TWITCHING & CONVULSIONS. Medical Cond Aggravated By Exposure: HYPERSENSITIVITY TO NEOMYCIN SULFATE OR THE AMINIOGLYCOSIDE GROUP OF ANTIBIOTICS; STREPTOMYCIN OR GENTAMICIN. IMPAIRED KIDNEY OR HEARING FUNCTION. First Aid: SKIN: WASH W/SOAP & WATER. EYES: FLUSH W/WATER FOR 15 MINS. INHALATION: REMOVE TO FRESH AIR. INGESTION: CONTACT A PHYSICIAN. OBTAIN MEDICAL ATTENTION IN ALL CASES. ======================================================= Handling and Disposal ======================================================= Spill Release Procedures: SCOOP OR VACUUM MATERIAL & PLACE IN CONTAINER. WASH SITE W/WATER WHEN MATERIAL PICKUP IS COMPLETE. Waste Disposal Methods: INCINERATION IN ACCORDANCE W/FEDERAL, STATE & LOCAL REGULATIONS. Handling And Storage Precautions: USE W/ADEQUATE VENTILATION. Other Precautions: DON'T GET IN EYES, EARS, ON SKIN OR ON CLOTHING. AVOID BREATHING DUST. AVOID EXPOSURE TO OPEN WOUNDS OR ABRADED SKIN. ======================================================= Fire and Explosion Hazard Information ======================================================= Extinguishing Media: WATER, CO2, DRY CHEMICAL Fire Fighting Procedures: WEAR SELF-CONTAINED BREATHING APPARATUS & FULL BODY PROTECTIVE EQUIPMENT. Unusual Fire/Explosion Hazard: AS W/ALL ORGANIC POWDERS (FINELY DIVIDED), IT IS ADVISABLE TO ELIMINATE EXPLOSION HAZARDS. (SEE SUPPLEMENTAL INFORMATION) ======================================================= Control Measures ======================================================= Respiratory Protection: USE APPROVED RESPIRATOR OR DUST MASK Ventilation: LOCAL EXHAUST Protective Gloves: RUBBER Eye Protection: SAFETY GLASSES W/SIDE SHIELDS Other Protective Equipment: COVERINGS OR OTHER EXPOSED AREAS OF SKIN Work Hygienic Practices: WASH THOROUGHLY AFTER HANDLING. Supplemental Safety and Health: UNUSUAL FIRE & EXPLOSION (CONT'D): USE GROUNDING MECHANICAL EQUIPMENT IN CONTACT W/MATERIAL TO DISSIPATE THE POTENTIAL BUILDUP OF STATIC ELECTRICITY, INERTING THE ATMOSPHERE OR CONTROLLING DUST LEVELS . ======================================================= Physical/Chemical Properties ======================================================= Solubility in Water: COMPLETE Appearance and Odor: AMORPHOUS WHITE POWDER, ODORLESS Percent Volatiles by Volume: 0 ======================================================= Reactivity Data ======================================================= Stability Indicator: YES Stability Condition To Avoid: HEAT Hazardous Decomposition Products: CO, SULFUR OXIDES Hazardous Polymerization Indicator: NO ======================================================= Toxicological Information ======================================================= ======================================================= Ecological Information ======================================================= ======================================================= MSDS Transport Information ======================================================= ======================================================= Regulatory Information ======================================================= ======================================================= Other Information ======================================================= ======================================================= HAZCOM Label ======================================================= Product ID: NEOMYCIN SULFATE Cage: GO374 Assigned IND: Y Company Name: UPJOHN CO THE Street: 7171 PORTAGE RD City: KALAMAZOO MI Zipcode: 49001-0199 Health Emergency Phone: 616-323-7555(D)/616-323-6722(24 HR) Date Of Label Review: 01/10/1994 Status Code: C Label Date: 01/10/1994 Origination Code: Z ======================================================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever expressly or implied warrants, states, or intends said information to have any application, use or viability by or to any person or persons outside the Department of Defense nor any person or persons contracting with any instrumentality of the United States of America and disclaims all liability for such use. Any person utilizing this instruction who is not a military or civilian employee of the United States of America should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation regardless of similarity to a corresponding Department of Defense or other government situation.