SAFETY DATA SHEET (MSDS) Date of Preparation or Revision: October 2, 2001 IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND COMPANY: Catalog Number: Product Name: Supplier: Telephone: Fax: Emergency Contact: 492015 NP-40 CALBIOCHEM® P.O. Box 12087 La Jolla, CA 92039-2087 (858) 450-5558 (800) 854-3417 (858) 453-3552 CHEMTREC® (800) 424-9300 (within U.S.A.) (703) 527-3887 (outside U.S.A.) COMPOSITION/INFORMATION ON INGREDIENTS: Polyethyleneglycol-p-isooctylphenyl Ether NP-40; Nonidet P40; Octylphenoxypolyethoxyethanol NP-40 Chemical Name: Synonyms: Hazardous Ingredient: HAZARDOUS IDENTIFICATION: Material may cause irritation to the eyes, skin, mucous membranes, and the upper respiratory tract. Exposure to material may cause severe damage to the eyes. FIRST AID MEASURES: In cases of skin contact, wash immediately with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes and wash before wearing. Consult a physician. In cases of eye contact, flush immediately with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Consult a physician. In cases of inhalation, remove to fresh air and monitor breathing. If breathing becomes difficult, give oxygen and consult a physician. If breathing stops, give artificial respiration and consult a physician. In cases of ingestion, wash mouth out with water and consult the local poison center and a physician. FIRE-FIGHTING MEASURE: Extinguishing Media: Dry chemical powder, carbon dioxide, water spray, alcohol or polymer foam. Special Fire Fighting Procedures: Wear self-contained breathing apparatus and full protective clothing to prevent contact with skin and eyes. Unusual Fire and Explosive Hazards: Upon thermal decomposition, it may EMIT TOXIC GASES. ACCIDENTAL RELEASE MEASURES: Steps to be Taken if Material is Released or Spilled: Evacuate area. Wear a respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Absorb material on sand or vermiculite. Sweep up and place in a suitable container. Avoid raising dust. Hold for appropriate disposal. Wash spill site and ventilate area after material pickup is complete. HANDLING AND STORAGE: Store in a tightly closed container in a cool, dry place (+20°C). Protect from moisture. Material is an irritant. Avoid contact with material. Avoid prolonged or repeated exposure. Lab should be equipped with a safety shower and an eye wash station. Wash thoroughly after handling material. 492015, Rev. 10-02-01 Page 1 of 2 EXPOSURE CONTROLS/PERSONAL PROTECTION: Protective Equipment: Wear suitable protective clothing, such as chemical resistant gloves and chemical safety goggles. Respiratory Protection and Ventilation: Use a NIOSH/MSHA approved respirator. Handle in a chemical fume hood with adequate ventilation. PHYSICAL AND CHEMICAL PROPERTIES: Clear colorless solution. N/A Appearance: Flash Point: STABILITY AND REACTIVITY: Stability: Stable under normal handling procedures. Incompatibilities and Conditions to Avoid: N/A Hazardous Combustion or Decomposition Products: Upon thermal decomposition, may emit toxic gases including carbon monoxide and carbon dioxide. TOXICOLOGICAL INFORMATION: Note: To the best of our knowledge, the toxicological properties of NP-40 have not been thoroughly investigated. Due to the nature of this compound, it is considered a potential health hazard. No RTECS number has been assigned to this product. RTECS Number: ECOLOGICAL INFORMATION: No information available. DISPOSAL CONSIDERATIONS: Country, federal, state, and local regulations are varied and change frequently. For this reason, we recommend that you contact your local Department of Health Services for information on the disposal of this product or arrange for disposal by a licensed disposal company. TRANSPORTATION INFORMATION: UN Number: N/A Proper Shipping Name: N/A IATA Class: N/A IATA Packing Group: N/A REGULATORY INFORMATION: X Risk Phrases: R36/37/38: Irritating to eyes, respiratory system and skin. Risk of serious damage to the eyes. R41: Safety Phrases: S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36: Wear suitable protective clothing. OTHER INFORMATION: Avoid contact with material. Avoid prolonged or repeated exposure. Wash thoroughly after handling. Material should only be handled by qualified, experienced professionals. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide for experienced personnel. CALBIOCHEM-NOVABIOCHEM Corporation shall not be held liable for any damage resulting from the handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. 492015, Rev. 10-02-01 Page 2 of 2