Material Safety Data Sheet o-Phenylenediamine dihydrochloride, 99+% ACC# 96177 Section 1 - Chemical Product and Company Identification MSDS Name: o-Phenylenediamine dihydrochloride, 99+% Catalog Numbers: AC218480000, AC218480250, AC218481000 Synonyms: 1,2-Benzenediamine dihydrochloride; 1,2-Phenylenediamine dihydrochloride. Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410 For information in North America, call: 800-ACROS-01 For emergencies in the US, call CHEMTREC: 800-424-9300 Section 2 - Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS 615-28-1 o-Phenylenediamine dihydrochloride >99 210-418-7 Section 3 - Hazards Identification EMERGENCY OVERVIEW Appearance: white to pale pink powder. Warning! Harmful if swallowed. Causes eye irritation. May cause allergic skin reaction. May be harmful if absorbed through skin or if inhaled. May cause methemoglobinemia. Dangerous for the environment. Target Organs: Blood, liver, eyes, skin. Potential Health Effects Eye: Causes eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. May cause an allergic reaction in certain individuals. Ingestion: May cause irritation of the digestive tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. Oral toxicity would be similar to that of parent compound, o-phenylenediamine, because the dihydrochloride would be formed when coming into contact with the hydrochloric acid of the stomach. Inhalation: May cause respiratory tract irritation. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. Chronic: May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death. o-Phenylenediamine dihydrochloride has produced liver tumors in 78-week feeding studies with rats and Section 4 - First Aid Measures Eyes: In case of contact, immediately flush eyes with plenty of water for a t least 15 minutes. Get medical aid. Skin: In case of contact, immediately flush skin with soap and plenty of water. Remove contaminated clothing and shoes. Get medical aid if symptoms occur. Wash clothing before reuse. Ingestion: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood. Section 5 - Fire Fighting Measures General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing Media: Use extinguishing media most appropriate for the surrounding fire. Flash Point: Not applicable. Autoignition Temperature: Not available. Explosion Limits, Lower:Not available. Upper: Not available. NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 0 Section 6 - Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - Handling and Storage Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs o-Phenylenediamine dihydrochloride none listed none listed none listed o-Phenylenediamine 0.1 mg/m3 TWA none listed none listed OSHA Vacated PELs: o-Phenylenediamine dihydrochloride: No OSHA Vacated PELs are listed for this chemical. o-Phenylenediamine: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - Physical and Chemical Properties Physical State: Powder Appearance: white to pale pink Odor: Not available. pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point:258 deg C (dec) Decomposition Temperature:258 deg C Solubility: Soluble. Specific Gravity/Density:Not available. Molecular Formula:C6H8N2.2HCl Molecular Weight:181.07 Section 10 - Stability and Reactivity Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Dust generation. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - Toxicological Information RTECS#: CAS# 615-28-1: ST0175000 CAS# 95-54-5: SS7875000 LD50/LC50: Not available. CAS# 95-54-5: Inhalation, mouse: LC50 = >91 mg/m3/4H; Inhalation, rat: LC50 = 1873 mg/m3; Oral, mouse: LD50 = 366 mg/kg; Oral, rat: LD50 = 510 mg/kg; Skin, rat: LD50 = >5 gm/kg; . Carcinogenicity: CAS# 615-28-1: * ACGIH: Not listed. * California: carcinogen, initial date 5/15/98 (listed as o-Phenylenediamine salts). * NTP: Not listed. * IARC: Not listed. CAS# 95-54-5: * ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to humans * California: carcinogen, initial date 5/15/98 * NTP: Not listed. * IARC: Not listed. Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Mutagenicity: See actual entry in RTECS for complete information. Neurotoxicity: No information available. Other Studies: Section 12 - Ecological Information No information available. Section 13 - Disposal Considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. Section 14 - Transport Information US DOT Canada TDG Shipping Name: PHENYLENEDIAMINES PHENYLENEDIAMINES Hazard Class: 6.1 6.1 UN Number: UN1673 UN1673 Packing Group: III III Section 15 - Regulatory Information US FEDERAL TSCA CAS# 615-28-1 is listed on the TSCA inventory. CAS# 95-54-5 is listed on the TSCA inventory. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules CAS# 95-54-5: 40 CFR 799.3300 Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. CERCLA Hazardous Substances and corresponding RQs None of the chemicals in this material have an RQ. SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ. SARA Codes CAS # 615-28-1: immediate, sudden release of pressure, reactive. CAS # 95-54-5: immediate. Section 313 This material contains o-Phenylenediamine dihydrochlo (CAS# 615-28-1, >99%),which is subject to the reporting requirements of Section 313 of SARA Title This material contains o-Phenylenediamine (CAS# 95-54-5, -%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE CAS# 615-28-1 is not present on state lists from CA, PA, MN, MA, FL, or NJ. CAS# 95-54-5 can be found on the following state right to know lists: New Jersey, Minnesota, Massachusetts. California Prop 65 The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act: WARNING: This product contains o-Phenylenediamine dihydrochloride, listed as `o-Phenylenediamine salts', a chemical known to the state of California to cause cancer. WARNING: This product contains o-Phenylenediamine, a chemical known to the state of California to cause cancer. California No Significant Risk Level: CAS# 615-28-1: 44 ęg/day NSRL CAS# 95-54-5: 26 ęg/day NSRL European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T N Risk Phrases: R 20/21 Harmful by inhalation and in contact with skin. R 25 Toxic if swallowed. R 36 Irritating to eyes. R 40 Limited evidence of a carcinogenic effect. R 43 May cause sensitization by skin contact. R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R 68 Possible risk of irreversible effects. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S 60 This material and its container must be disposed of as hazardou s waste. S 28A After contact with skin, wash immediately with plenty of water . S 61 Avoid release to the environment. Refer to special instructions /safety data sheets. WGK (Water Danger/Protection) CAS# 615-28-1: No information available. CAS# 95-54-5: 3 Canada - DSL/NDSL CAS# 615-28-1 is listed on Canada's DSL List. CAS# 95-54-5 is listed on Canada's DSL List. Canada - WHMIS This product has a WHMIS classification of D1B, D2B. This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations. Canadian Ingredient Disclosure List CAS# 615-28-1 is not listed on the Canadian Ingredient Disclosure List. CAS# 95-54-5 is listed on the Canadian Ingredient Disclosure List. Section 16 - Additional Information MSDS Creation Date: 11/20/1998 Revision #4 Date: 8/28/2007 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.