Page 1 of 5 @Beckman Coulter® MATERIAL SAFETY DATA SHEET Section 1 Company and Product Identification Product Name Ready Safe? Part Number 141349, 158735, 266785 Doc. ID 141349-75 AE Issued (year/month/day) Revised (year/month/day) 2006/08/10 Series Name Liquid Scintillation consumables Manufacturer Beckman Coulter, Inc. 4300 Harbor Blvd. Fullerton, CA 92835-3100, U.S.A. ECREP Address: Beckman Coulter Ireland, Inc. Mervue Business Park, Mervue, Galway, Ireland 353 91 774068 Distributor and Emergency Phone No.  Refer to attached list, Document ID: 472050, for local distributor and emergency phone numbers. Section 2 Composition and Information on Ingredients Hazardous Ingredients: Meets Hazardous Criteria: Chemical Name CAS # % by wt. EU US OSHA WHMIS 1-Phenyl-1-Xylylethane 6196-95-8 <60 Xn;R65-36/38 Yes Yes Alkylphenol Ethoxylate 9016-45-9 <40 Xi;R36/37/38 Yes Yes See Section 15 Regulatory Information for additional information on hazard classifications. Section 3 Hazards Identification Emergency Overview Faint violet; Clear; Liquid; Aromatic Nonflammable Skin and eye irritant. Inhalation of vapors may cause repiratory irritation and nervous system effects. Physical Hazards None identified. Potential Health Effects Summary Contact may cause moderate to severe irritation to the eyes, skin and mucous membranes. Vapors may cause irritation to the eyes, respiratory tract and nervous system depression. Swallowing may result in aspiration of this product into the lungs and serious lung damage. See Section 11 Toxicological Information for more detailed health information. Product Hazard Classifications EU: Xn;R65-36/38 WHMIS: D2B US OSHA: Hazardous ?2006 Beckman Coulter, Inc. Global MSDS – English Ready Safe? MSDS # 141349-75 AE Page 2 of 5 Section 3 Hazards Identification (Continued) Beckman Coulter Safety Rating Flammability (Section V): 0 Health (Section XI): 2 Reactivity with Water (Section X): 0 Contact (Section VIII): 2 Code 0=none 1=slight 2=caution 3=severe Section 4 First Aid Measures Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not breathing, begin artificial respiration immediately and obtain medical attention. Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or longer, making sure that the eyelids are held open. If pain or irritation occur, obtain medical attention. Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical attention. Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical attention. Section 5 Fire Fighting Measures Flash Point 163°C(325.4°F) Flammable Limits Not available Autoignition Temp. Not available Extinguishing Media Use extinguishing media suitable for surrounding fire. Special Fire and Explosion Hazards None identified. Hazardous Combustion Products No information available. Protective Equipment for Firefighters Self-contained breathing apparatus is recommended for firefighters. Section 6 Accidental Release Measures Personal Precautions Eye protection and impervious clothing should be worn. Respiratory protection may be required if spill is in a confined area or generates vapor concentrations above acceptable levels. Spill and Leak Procedures Ventilate area. Remove all sources of ignition. Contain spill and collect with inert absorbent and place in a suitable container for disposal. Environmental Precautions Contain spill to prevent migration. Section 7 Handling and Storage Handling Precautions Use good laboratory procedures. Avoid contact with eyes, skin and clothing. Avoid creating and breathing of mists. Recommended Storage Conditions To maintain efficacy, store according to the instructions in the product labeling. Keep away from incompatible material (see Section 10). Ready Safe? MSDS # 141349-75 AE Page 3 of 5 Section 8 Exposure Controls and Personal Protection Exposure Limits US OSHA: None established ACGIH: None established DFG MAK: None established Engineering Controls No special engineering controls are required. Use with good general ventilation. Respiratory Protection Under normal conditions, the use of this product should not require respiratory protection. If aerosols are generated during use, the use of respiratory protection should be evaluated by a qualified professional. Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact. Skin Protection Impervious gloves, such as Nitrile or equivalent, should be worn to prevent skin contact. Section 9 Physical and Chemical Properties Physical State Liquid Color Faint violet Transparency Clear Odor Aromatic Odor Threshold Not applicable pH Not available Boiling Point 300°C(572°F) Melting Point Not available Specific Gravity ˜1 @20°C Vapor Pressure 1 mm Hg @20°C Vapor Density 7 (air=1) Evaporation Rate Not available Solubility Water Disperses in water Organic Not available Section 10 Stability and Reactivity Stability Stable in closed containers under normal temperatures and pressures. Hazardous Incompatibilities Strong oxidizers Strong acids Strong bases Hazardous Decomposition Products When stored as labeled, no known hazardous decomposition products are formed during the shelf-life of this product. Ready Safe? MSDS # 141349-75 AE Page 4 of 5 Section 10 Stability and Reactivity (Continued) Conditions to Avoid Keep away from incompatible material. Section 11 Toxicological Information Toxicity Data for Hazardous Ingredients Alkylphenol Ethoxylate MD0900000:Glycols, polyethylene, mono(nonylphenyl) ether (10/1/97) Oral LD50 Rat : 1310 mg/kg Oral LD50 Mouse : >50 gm/kg Dermal LD50 Rabbit : 2 mL/kg Primary Routes of Exposure Eye contact, ingestion, inhalation, and skin contact. Potential Effects of Acute Exposure Eye and skin contact may cause moderate to severe irritation. Inhalation of mists may cause irritation to the mucous membranes and respiratory tract. Ingestion may cause mucous membrane and gastrointestinal irritation with nausea, vomiting and abdominal pain. Potential Effects of Chronic Exposure Effects are similar to those for acute exposure. Symptoms of Overexposure Symptoms of contact include stinging sensation, redness, pain and swelling. Symptoms of inhalation exposure include cough, runny nose, difficulty breathing, shortness of breath, sore throat, headache, dizziness, drowsiness, incoordination, fatigue, loss of consciousness and coma. Carcinogenicity This product does not contain a reportable concentration (= 0.1%) of any ingredient listed as carcinogen by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I. Other Effects None identified. Conditions Aggravated by Exposure Individuals with eye, respiratory and skin disorders may find these conditions aggravated by exposure to this product. Section 12 Ecological Information Ecotoxicity No information available. Biodegradability No information available. Mobility No information available. Section 13 Disposal Considerations Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance with federal, state and local regulations. If unsure of the applicable requirements, contact the authorities for information. Section 14 Transport Information Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG. Ready Safe? MSDS # 141349-75 AE Page 5 of 5 Section 15 Regulatory Information US Federal and State Regulations SARA 313 Ethylene Oxide is subject to reporting requirements of Section 313, Title III of SARA. CERCLA RG’s, 40 CFR 302.4 Ethylene Oxide is listed. California Proposition 65 Ethylene Oxide has been identified by the State of California to cause cancer and reproductive harm. The State of California has adopted a regulation which requires a warning be given to individuals who may be exposed to chemicals identified by the State to cause cancer or reproductive harm. Accordingly, Beckman Coulter advises you of the following warning: WARNING: This product contains a chemical known to the State of California to cause cancer and reproductive harm. Massachusetts MSL Ethylene Oxide is listed. New Jersey Dept. of Health RTK List Ethylene Oxide is listed. Pennsylvania RTK Ethylene Oxide is listed. EU Labeling Classification Classification Risk and Safety Phrases Xn Harmful R36/37/38 Irritating to eyes, respiratory system and skin. R65 Harmful: may cause lung damage is swallowed. S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer). S24/25 Avoid contact with skin and eyes. S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. Canada WHMIS Classification: D2B—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Toxic (Skin Irritation) D2B—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Toxic (Eye Irritation) PIN: Not applicable Ingredients on Ingredient Disclosure List: Ethylene Oxide Ingredients with unknown toxicological properties: None Section 16 Other Information For further information, please contact your local Beckman Coulter representative. WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANYWAY FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS. Printed in U.S.A.