Page 1/6 Material Safety Data Sheet Printing date 01/17/2008 Reviewed on 01/16/2008 DR 1 Identification of substance: · Product details: · Trade name: Reduction Moderator Solution · Catalog or product number: 1610463, 1610463EDU · Application of the substance / the preparation Laboratory chemicals · Manufacturer/Supplier: Bio-Rad Laboratories, Life Science Group 2000 Alfred Nobel Drive Hercules, California 94547 (510)741-1000 · Information department: Technical services, customer support. · Emergency information: 1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT. 510-741-1000 2 Composition/Information on components: · Chemical characterization · Description: Mixture of the substances listed below with non-hazardous additions. · Listing of dangerous and non-hazardous components: CAS: 7732-18-5 EINECS: 231-791-2 RTECS: ZC 0110000 water 50-100% CAS: 12027-43-9 Tungstosilicic acid hydrate Xi; R 36/37/38 5-10% · Additional information For the wording of the listed risk phrases refer to section 15. * 3 Hazards identification · Emergency overview: Corrosive. May cause irreversible eye damage. C Corrosive · Information pertaining to particular dangers for man and environment The product has to be labelled due to the calculation procedure of the "General Classification guideline for preparations of the EU" in the latest valid version. R 34 Causes burns. · Classification system The classification was made according to the latest editions of the EU-lists, and expanded upon from company and literature data. 4 First aid measures · General information Immediately remove any clothing soiled by the product. · After inhalation In case of unconsciousness place patient stably in side position for transportation. · After skin contact Immediately wash with water and soap and rinse thoroughly. · After eye contact Rinse opened eye for several minutes under running water. Then consult a doctor. · After swallowing Drink copious amounts of water and provide fresh air. Immediately call a doctor. USA (Contd. on page 2) Page 2/6 Material Safety Data Sheet Printing date 01/17/2008 Reviewed on 01/16/2008 Trade name: Reduction Moderator Solution (Contd. of page 1) DR 5 Fire fighting measures · Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. · Protective equipment: No special measures required. 6 Accidental release measures · Person-related safety precautions: Wear protective equipment (See section 8). Keep unprotected persons away. · Measures for environmental protection: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. · Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Use neutralizing agent. Dispose contaminated material as waste according to item 13. Ensure adequate ventilation. 7 Handling and storage · Handling · Information for safe handling: No special measures required. Ensure good ventilation/exhaustion at the workplace. Prevent formation of aerosols. No special precautions are necessary if used correctly. · Information about protection against explosions and fires: No special measures required. · Storage · Requirements to be met by storerooms and receptacles: According to product specification · Information about storage in one common storage facility: Not required. · Further information about storage conditions: Keep receptacle tightly sealed. * 8 Exposure controls and personal protection · Additional information about design of technical systems: No further data; see item 7. · Components with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. · Additional information: The lists that were valid during the creation were used as basis. · Personal protective equipment · General protective and hygienic measures Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. · Breathing equipment: In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air. · Protection of hands: Protective gloves. (Contd. on page 3) USA Page 3/6 Material Safety Data Sheet Printing date 01/17/2008 Reviewed on 01/16/2008 Trade name: Reduction Moderator Solution (Contd. of page 2) DR · Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Synthetic gloves · Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. · Eye protection: Safety glasses Tightly sealed goggles. * 9 Physical and chemical properties: · General Information Form: liquid Color: Colorless Odor: Odorless · Change in condition Melting point/Melting range: undetermined Boiling point/Boiling range: 100°C · Flash point: Not applicable · Auto igniting: Product is not selfigniting. · Danger of explosion: Product does not present an explosion hazard. · Vapor pressure at 20°C: 23 hPa · Density: Not determined · Solubility in / Miscibility with Water: Fully miscible · pH-value at 20°C: 1.5 · Solvent content: · Organic solvents: 0.0 % · Water: 90.0 % · Solids content: 10.0 % 10 Stability and reactivity · Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. · Dangerous reactions No dangerous reactions known · Dangerous products of decomposition: No dangerous decomposition products known 11 Toxicological information · Acute toxicity: · Primary irritant effect: · on the skin: Caustic effect on skin and mucous membranes. (Contd. on page 4) USA Page 4/6 Material Safety Data Sheet Printing date 01/17/2008 Reviewed on 01/16/2008 Trade name: Reduction Moderator Solution (Contd. of page 3) DR · on the eye: Strong caustic effect. · Sensitization: No sensitizing effects known. · Additional toxicological information: The product shows the following dangers according to the calculation method of the General EU Classification Guidelines for Preparations as issued in the latest version: Corrosive Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of esophagus and stomach. · Target organs: Skin. 12 Ecological information: · General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. Must not reach bodies of water or drainage ditch undiluted or unneutralized. Rinse off of bigger amounts into drains or the aquatic environment may lead to decreased pH-values. A low pH-value harms aquatic organisms. In the dilution of the use-level the pH-value is considerably increased, so that after the use of the product the aqueous waste, emptied into drains, is only low water-dangerous. 13 Disposal considerations · Product: · Recommendation Hand over to hazardous waste disposers. Must not be disposed of together with household garbage. Do not allow product to reach sewage system. · Uncleaned packagings: · Recommendation: Disposal must be made according to official regulations. · Recommended cleansing agent: Water, if necessary with cleansing agents. 14 Transport information · DOT regulations: · Hazard class: - · Land transport ADR/RID (cross-border) · ADR/RID class: - · Maritime transport IMDG: · IMDG Class: - · Marine pollutant: No · Air transport ICAO-TI and IATA-DGR: · ICAO/IATA Class: - USA (Contd. on page 5) Page 5/6 Material Safety Data Sheet Printing date 01/17/2008 Reviewed on 01/16/2008 Trade name: Reduction Moderator Solution (Contd. of page 4) DR * 15 Regulations · SARA (Superfund Amendents and Reauthorization Act of 1986 - USA) · Section 302/304 (40CFR355.30 / 40CFR355.40): None of the ingredients is listed. · Section 313 (40CFR372.65): None of the ingredients is listed. · TSCA (Toxic Substances Control Act): 7732-18-5 water · Cancerogenity categories · EPA (Environmental Protection Agency) None of the ingredients is listed. · IARC (International Agency for Research on Cancer) None of the ingredients is listed. · NTP (National Toxicology Program) None of the ingredients is listed. · TLV (Threshold Limit Value established by ACGIH) None of the ingredients is listed. · MAK (German Maximum Workplace Concentration) None of the ingredients is listed. · NIOSH-Ca (National Institute for Occupational Safety and Health) None of the ingredients is listed. · OSHA-Ca (Occupational Safety & Health Administration) None of the ingredients is listed. · Markings according to EU guidelines: The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials · Code letter and hazard designation of product: C Corrosive · Risk phrases: 34 Causes burns. · Safety phrases: 23 Do not breathe gas/fumes/vapour/spray. 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. 45 In case of accident or if you feel unwell, seek medical advice immediately. 60 This material and its container must be disposed of as hazardous waste. · National regulations · Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water. 16 Other information: This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. · Department issuing MSDS: Environmental Health and Safety. (Contd. on page 6) USA Page 6/6 Material Safety Data Sheet Printing date 01/17/2008 Reviewed on 01/16/2008 Trade name: Reduction Moderator Solution (Contd. of page 5) DR · Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000 Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000 · * Data compared to the previous version altered. USA