QIAGEN INC -- RNASE A SOLUTION, 12125 ======================================================= MSDS Safety Information ======================================================= FSC: 6550 NIIN: 01-399-1142 MSDS Date: 09/22/1997 MSDS Num: CJMLX Product ID: RNASE A SOLUTION, 12125 MFN: 01 Responsible Party Cage: 01QTQ Name: QIAGEN INC Address: 28159 AVE STANFOR City: SANTA CLARITA CA 91355 Info Phone Number: 800-362-7737 Emergency Phone Number: 800-362-7737 Review Ind: Y Published: Y ======================================================= Contractor Summary ======================================================= Cage: 01QTQ Name: QIAGEN INC Address: 28159 AVENUE STANFORD City: SANTA CLARITA CA 91355 Phone: 800-362-7737 ======================================================= Item Description Information ======================================================= Item Name: KIT,PURIFICATION ======================================================= Ingredients ======================================================= Cas: 9001-99-4 RTECS #: RF0760000 Name: RIBONUCLEASE A ======================================================= Health Hazards Data ======================================================= Route Of Entry Inds - Inhalation: YES Skin: YES Ingestion: YES Carcinogenicity Inds - NTP: NO IARC: NO OSHA: NO Effects of Exposure: ACUTE: IRRITATING TO EYES, RSPIRATORY SYSTEM, AND SKIN. MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. Signs And Symptions Of Overexposure: SEE HEALTH HAZARDS. First Aid: EYE CONT: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING OF EYES BY SEPARATING THE EYELIDS WITH FINGERS. SKIN CONT: IMMEDIATELY WASH WITH SOAP AND CO PIOUS AMOUNTS OF WATER. INHAL: REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. INGEST: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS . CALL A PHYSICIAN. REMOVE AND WASH CONTAMINATED CLOTHING PROMPTLY. ======================================================= Handling and Disposal ======================================================= Spill Release Procedures: PRECAUTIONARY MEASURES: WEAR NIOSH APPRVD SCBA, CHEMICAL SAFETY GOGGS, RUBBER BOOTS, AND HEAVY RUBBER GLOVES. CLEAN-UP PROCEDURE: SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID DUST. VENT ILATE AREA AND WASH SPILL SITE AFTER MATEIRAL PICKUP IS COMPLETE. Waste Disposal Methods: NO SPECIAL DISPOSAL METHOD REQUIRED. OBSERVE ALL FEDERAL, STATE, AND LOCAL LAWS. Handling And Storage Precautions: STORE TIGHTLY CLOSED AT 20-25 C. DO NOT GET IN EYES, ON SKIN, OR ON CLOTHING. DO NOT BREATHE VAPOR. STORE IN A DRY PLACE. Other Precautions: THE PRODUCT SHOULD BE HANDLED WITH THE NORMAL CAUTION ACCORDED CHEMICALS. ADDITIONAL HARMFUL PROPERTIES CANNOT BE RULED OUT. ======================================================= Fire and Explosion Hazard Information ======================================================= Extinguishing Media: CARBON DIOXIDE, DRY CHEMICAL POWDER, OR APPROPRIATE FOAM. Fire Fighting Procedures: USE NIOSH APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT (FP N). ======================================================= Control Measures ======================================================= Respiratory Protection: NIOSH APPROVED RESPIRATOR. Ventilation: MECHANICAL EXHAUST REQUIRED. Protective Gloves: RUBBER GLOVES. Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES (FP N). Other Protective Equipment: ANSI APPROVED EYE WASH & DELUGE SHOWER (FP N). Work Hygienic Practices: WASH THORUGHLY AFTER HANDLING. ======================================================= Physical/Chemical Properties ======================================================= Solubility in Water: SOLUBLE Appearance and Odor: COLORLESS LIQUID. NO ODOR. ======================================================= Reactivity Data ======================================================= Stability Indicator: YES Materials To Avoid: NONE. Hazardous Decomposition Products: NONE. Hazardous Polymerization Indicator: NO ======================================================= Toxicological Information ======================================================= Toxicological Information: TOXICITY DATA: N/A. ACUTE EFFECTS. INHALATION: MAY BE HARMFUL BY INHALATION. EYE CONT: MAY CAUSE EYE IRRITATION. SKIN CONT: MAY CAUSE SKIN IRRITATION. INGEST: MAY BE HARMFUL IF SWALLOWED. PROLONGED EX POSURE: N/A. CHRONIC EFFECTS: N/A. ======================================================= Ecological Information ======================================================= Ecological: NO DATA AVAILABLE. HOWEVER, THE SUBSTANCE IS READILY BIODEGRADABLE. ======================================================= MSDS Transport Information ======================================================= ======================================================= Regulatory Information ======================================================= Federal Regulatory Information: LABELING: XN, HARMFUL, R 36/37/38-42/43. ======================================================= Other Information ======================================================= Other Information: CHEMICAL CHARACTERISTICS: AQUEOUS SOLUTION OF 100 MG/ML RNASE A. SOURCE: BOVINE PANCREAS. CLASSIFICATION OF SUBSTANCE: XN (HARMFUL). ======================================================= HAZCOM Label ======================================================= Product ID: RNASE A SOLUTION, 12125 Cage: 01QTQ Company Name: QIAGEN INC Street: 28159 AVENUE STANFORD City: SANTA CLARITA CA Zipcode: 91355 Health Emergency Phone: 800-362-7737 Label Required IND: Y Date Of Label Review: 08/31/1999 Status Code: A Origination Code: F Chronic Hazard IND: Y Eye Protection IND: YES Skin Protection IND: YES Signal Word: CAUTION Respiratory Protection IND: YES Health Hazard: Slight Contact Hazard: Slight Fire Hazard: None Reactivity Hazard: None Hazard And Precautions: ACUTE: IRRITATING TO EYES, RSPIRATORY SYSTEM, AND SKIN. CHRONIC: MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. ======================================================= Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever expressly or implied warrants, states, or intends said information to have any application, use or viability by or to any person or persons outside the Department of Defense nor any person or persons contracting with any instrumentality of the United States of America and disclaims all liability for such use. Any person utilizing this instruction who is not a military or civilian employee of the United States of America should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation regardless of similarity to a corresponding Department of Defense or other government situation.