MSDS Number: M1157 * * * * * Effective Date: 08/20/08 * * * * * Supercedes: 12/06/05 MERCAPTOACETIC ACID 1. Product Identification Synonyms: Thioglycolic acid; 2-mercaptoacetic acid. CAS No.: 68-11-1 Molecular Weight: 92.12 Chemical Formula: HSCH2COOH Product Codes: J.T. Baker: P601 Mallinckrodt: 1903 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Thioglycolic Acid 68-11-1 100% Yes 3. Hazards Identification Emergency Overview -------------------------- DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. SAF-T-DATA(tm) Ratings (Provided here for your convenience) ----------------------------------------------------------------------------------------------------------- Health Rating: 3 - Severe Flammability Rating: 1 - Slight Reactivity Rating: 2 - Moderate Contact Rating: 4 - Extreme (Corrosive) Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES Storage Color Code: White (Corrosive) ----------------------------------------------------------------------------------------------------------- Potential Health Effects ---------------------------------- Inhalation: Vapors irritate the nose, mucous membranes, and upper respiratory tract. The sense of smell may become rapidly fatigued when handling this compound at elevated temperatures. Can cause burns, and in severe cases, death. Ingestion: Toxic by ingestion. Causes irritation and burns to the gastrointestinal tract. May cause weakness, shortness of breath, convulsions, and death. Skin Contact: Corrosive. Causes burns to the skin. May be absorbed through the skin in toxic amounts; Symptoms will parallel those from ingestion. Sufficient quantities can cause death. Eye Contact: Corrosive. Vapors irritate the eyes. Liquid causes burns, eye damage. Lachrymator; causes tearing with severe irritation. Chronic Exposure: Chronic skin exposure to small amounts may cause a skin rash. Aggravation of Pre-existing Conditions: No information found. 4. First Aid Measures Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately. Ingestion: If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Get medical attention immediately. Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse. Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately. 5. Fire Fighting Measures Fire: Flash point: > 113C (> 235F) As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source. Explosion: Above the flash point, explosive vapor-air mixtures may be formed. Fire Extinguishing Media: Use carbon dioxide, dry chemical, or foam. This material may react violently with water. Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. 6. Accidental Release Measures Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Neutralize with alkaline material (soda ash, lime), then absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! Remove all sources of ignition. 7. Handling and Storage Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: -ACGIH Threshold Limit Value (TLV): 1 ppm (TWA) skin Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus. Breathing air quality must meet the requirements of the OSHA respiratory protection standard (29CFR1910.134). Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area. 9. Physical and Chemical Properties Appearance: Clear, colorless liquid. Odor: Strong unpleasant odor. Solubility: Miscible in water. Specific Gravity: 1.33 @ 20C pH: No information found. % Volatiles by volume @ 21C (70F): No information found. Boiling Point: 120C (248F) @ 20 mm Hg Melting Point: -16C (3F) Vapor Density (Air=1): 3.2 Vapor Pressure (mm Hg): 1 @ 60C (140F) Evaporation Rate (BuAc=1): No information found. 10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Readily oxidized by air. Hazardous Decomposition Products: Burning may produce sulfur oxides, carbon monoxide, carbon dioxide, and hydrogen sulfide gas. Hazardous Polymerization: Will not occur. Incompatibilities: Strong oxidizers. Conditions to Avoid: Air, heat, incompatibles 11. Toxicological Information Oral rat LD50: 114 mg/Kg Inhalation rat LC50: 210 mg/m3/4H. --------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- Thioglycolic Acid (68-11-1) No No None 12. Ecological Information Environmental Fate: No information found. Environmental Toxicity: No information found. 13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements. 14. Transport Information Domestic (Land, D.O.T.) ----------------------- Proper Shipping Name: THIOGLYCOLIC ACID Hazard Class: 8 UN/NA: UN1940 Packing Group: II Information reported for product/size: 500G International (Water, I.M.O.) ----------------------------- Proper Shipping Name: THIOGLYCOLIC ACID Hazard Class: 8 UN/NA: UN1940 Packing Group: II Information reported for product/size: 500G International (Air, I.C.A.O.) ----------------------------- Proper Shipping Name: THIOGLYCOLIC ACID Hazard Class: 8 UN/NA: UN1940 Packing Group: II Information reported for product/size: 500G 15. Regulatory Information --------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- Thioglycolic Acid (68-11-1) Yes Yes Yes Yes --------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- Thioglycolic Acid (68-11-1) Yes Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- Thioglycolic Acid (68-11-1) No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCA- Ingredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ Thioglycolic Acid (68-11-1) No No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No Reactivity: No (Pure / Liquid) Australian Hazchem Code: 2X Poison Schedule: None allocated. WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR. 16. Other Information NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0 Label Hazard Warning: DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. Label Precautions: Do not breathe vapor or mist. Do not get in eyes, on skin, or on clothing. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. Label First Aid: In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. In all cases get medical attention immediately. Product Use: Laboratory Reagent. Revision Information: No Changes. Disclaimer: ************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION. ************************************************************************************************ Prepared by: Environmental Health & Safety Phone Number: (314) 654-1600 (U.S.A.)