DL-METHIONINE DL-METHIONINE MSDS Number: M2106 --- Effective Date: 11/17/99 1. Product Identification Synonyms: 2-Amino-4-(methylthio)butric acid; Met; Methilonin; Acimetion CAS No.: 59-51-8 Molecular Weight: 149.22 Chemical Formula: C5H11NO2S Product Codes: P725 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------- --------- dl-Methionine 59-51-8 99 - 100% Yes 3. Hazards Identification Emergency Overview -------------------------- WARNING! MAY FORM COMBUSTIBLE DUST CONCENTRATIONS IN AIR. J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience) ----------------------------------------------------------------------------------------------------------- Health Rating: 0 - None Flammability Rating: 1 - Slight Reactivity Rating: 0 - None Contact Rating: 1 - Slight Lab Protective Equip: GOGGLES; LAB COAT Storage Color Code: Orange (General Storage) ----------------------------------------------------------------------------------------------------------- Potential Health Effects ---------------------------------- Inhalation: No adverse health effects expected from inhalation. Ingestion: Large doses may cause gastro-intestinal upset. Skin Contact: No adverse effects expected. Eye Contact: No adverse effects expected. Chronic Exposure: No information found. Aggravation of Pre-existing Conditions: No information found. 4. First Aid Measures Inhalation: Not expected to require first aid measures. Ingestion: If large amounts were swallowed, give water to drink and get medical advice. Skin Contact: Wash exposed area with soap and water. Get medical advice if irritation develops. Eye Contact: Wash thoroughly with running water. Get medical advice if irritation develops. 5. Fire Fighting Measures Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source. Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Minimum explosible concentration in air: 0.025 g/l Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide. Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. 6. Accidental Release Measures Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container. 7. Handling and Storage Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: None established. Ventilation System: Not expected to require any special ventilation. Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. Skin Protection: Wear protective gloves and clean body-covering clothing. Eye Protection: Safety glasses. 9. Physical and Chemical Properties Appearance: White powder. Odor: Faint acid odor. Solubility: ca. 18 gm/l Specific Gravity: 1.340 pH: 5.6 - 6.1 (1% aqueous solution) % Volatiles by volume @ 21C (70F): 0 Boiling Point: Not applicable. Melting Point: 281C (538F) Vapor Density (Air=1): No information found. Vapor Pressure (mm Hg): No information found. Evaporation Rate (BuAc=1): No information found. 10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Hazardous Decomposition Products: Burning may produce carbon monoxide, carbon dioxide, sulfur oxides, and nitrogen oxides. Hazardous Polymerization: Will not occur. Incompatibilities: Strong oxidizers. Conditions to Avoid: Heat, flame, ignition sources, dusting and incompatibles. 11. Toxicological Information No LD50/LC50 information found relating to normal routes of occupational exposure. Investigated as a mutagen, reproductive effector. --------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- dl-Methionine (59-51-8) No No None 12. Ecological Information Environmental Fate: No information found. Environmental Toxicity: No information found. 13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements. 14. Transport Information Not regulated. 15. Regulatory Information --------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- dl-Methionine (59-51-8) Yes Yes Yes Yes --------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- dl-Methionine (59-51-8) No Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- dl-Methionine (59-51-8) No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCA- Ingredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ dl-Methionine (59-51-8) No No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: No Chronic: No Fire: Yes Pressure: No Reactivity: No (Pure / Solid) Australian Hazchem Code: No information found. Poison Schedule: No information found. WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR. 16. Other Information NFPA Ratings: Health: 0 Flammability: 1 Reactivity: 0 Label Hazard Warning: WARNING! MAY FORM COMBUSTIBLE DUST CONCENTRATIONS IN AIR. Label Precautions: Store in a tightly closed container. Avoid dust cloud in presence of an ignition source. Maintain adequate ventilation. As part of good industrial and personal hygiene and safety procedure, avoid all unnecessary exposure to the chemical substance and ensure prompt removal from skin, eyes and clothing. Label First Aid: Not applicable. Product Use: Laboratory Reagent. Revision Information: No changes. Disclaimer: ************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION. ************************************************************************************************ Prepared by: Strategic Services Division Phone Number: (314) 539-1600 (U.S.A.)