1 Page:
U-73122
MATERIAL SAFETY DATA SHEET
07/30/2004
08/07/2005
07/30/2004
Date Created:
Revision:
Supercedes Revision:
08/07/2005 Printed:
Cayman Chemical Company
1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
1. Product and Company Identification
Product Code: 70740
Product Name: U-73122
Manufacturer Information
Company Name: Cayman Chemical Company
Emergency Contact: Cayman Chemical Company (800)364-9897
Information: Cayman Chemical Company (734)971-3335
Chemical Family: Inhibtiors
CAS Number: 112648-68-7
Synonyms: 1-[6-[[(17.beta.)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]
hexyl]-1H-pyrrole-2,5-dione;
2. Composition/Information on Ingredients
U-73122
Hazardous Components (Chemical Name)
112648-68-7
CAS #
100.0 %
Percentage
No data.
OSHA PEL
No data.
ACGIH TLV
No data.
Other Limits
1.
3. Hazards Identification
Emergency Overview: No data available.
Route(s) of Entry: Inhalation? Yes Skin? Yes Eyes? Yes Ingestion? Yes Other: Injection
Potential Health Effects (Acute and Chronic): Material may be irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye, skin, or respiratory system irritation.
The toxicological properties of this compound have not been fully evaluated.
Signs and Symptoms Of Exposure: No data available.
4. First Aid Measures
Emergency and First Aid Procedures: If inhaled remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
If swallowed, wash out mouth with water provided person is conscious. Never give anything by
mouth to an unconscious person. Get medical attention. Do NOT induce vomiting unless directed
to do so by medical personnel.
In case of contact with eyes, hold eyelids apart and flush eyes with plenty of water. After initial
flushings, remove any contact lenses and continue flushing for at least 20 minutes. Have eyes
examined and tested by medical personnel.
In case of skin contact, immediately wash skin with soap and plenty of water. Remove
contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
5. Fire Fighting Measures
Flash Pt: No data.
Explosive Limits: LEL: No data. UEL: No data.
Autoignition Pt: No data.
Fire Fighting Instructions: As in any fire, wear self-contained breathing apparatus pressure-demand (MSHA/NIOSH
approved or equivalent), and full protective gear to prevent contact with skin and eyes.
Flammable Properties and Hazards: No data available.
Extinguishing Media: Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray when fighting fires
involving this material.
Unsuitable Extinguishing Media: No data available.
ANSI Z400.1 Format
08/07/2005 Revision:
08/07/2005 Printed:
2 Page:
U-73122
MATERIAL SAFETY DATA SHEET
07/30/2004 Supercedes Revision:
6. Accidental Release Measures
Steps To Be Taken In Case Material Is
Released Or Spilled:
Wear a NIOSH/MSHA approved self-contained breathing apparatus and appropriate personal
protection (rubber boots, safety goggles, and heavy rubber gloves).
Vacuum or sweep up material and place in disposal container.
Avoid raising dust.
After removal, ventilate contaminated area and flush thoroughly with water.
7. Handling and Storage
Hazard Label Information: Avoid contact with skin and eyes. Do not reuse this container. Use with adequate ventilation.
Wash thoroughly after handling.
Precautions To Be Taken in Handling: Avoid breathing (dust, vapor, mist, gas).
Avoid contact with eyes, skin, and clothing.
Avoid prolonged or repeated exposure.
Do not reuse this container.
Use with adequate ventilation.
Wash thoroughly after handling.
Precautions To Be Taken in Storing: Store at correct temperature.
8. Exposure Controls/Personal Protection
Protective Equipment Summary - Hazard
Label Information:
Eye wash station in work area Lab coat Latex disposable gloves Safety glasses Safety
shower in work area Vent Hood
Respiratory Equipment (Specify Type): No data available.
Eye Protection: Safety glasses
Protective Gloves: Latex disposable gloves
Other Protective Clothing: Lab coat
Engineering Controls (Ventilation etc.): Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Work/Hygienic/Maintenance Practices: Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a
safety shower.
Wash thoroughly after handling.
9. Physical and Chemical Properties
Physical States: [ ] Gas [ ] Liquid [ X ] Solid
Melting Point: 121.00 C - 122.00 C
Boiling Point: No data.
Autoignition Pt: No data.
Flash Pt: No data. Method:
Explosive Limits: LEL: No data. UEL: No data.
Specific Gravity (Water = 1): No data.
Vapor Pressure (vs. Air or mm Hg): No data.
Vapor Density (vs. Air = 1): No data.
Evaporation Rate (vs Butyl Acetate=1): No data.
Solubility in Water: Insoluble* at 25.0 C
Other Solubility Notes: *PBS pH 7.2, sol. in DMSO, & DMF
Percent Volatile: No data.
Corrosion Rate: No data.
Formula: C29H40N2O3
Molecular Weight: 464.60
pH: No data.
Appearance and Odor: A crystalline solid
ANSI Z400.1 Format
08/07/2005 Revision:
08/07/2005 Printed:
3 Page:
U-73122
MATERIAL SAFETY DATA SHEET
07/30/2004 Supercedes Revision:
10. Stability and Reactivity
Stability: Unstable [ ] Stable [ X ]
Conditions To Avoid - Instability: No data available.
Incompatibility - Materials To Avoid: No data available.
Hazardous Decomposition Or Byproducts: No data available.
Hazardous Polymerization: Will occur [ ] Will not occur [ X ]
Conditions To Avoid - Hazardous
Polymerization:
No data available.
11. Toxicological Information
Toxicological Information: The toxicological effects of this compound have not been thoroughly studied.
Carcinogenicity/Other Information: No data available.
Carcinogenicity: NTP? No IARC Monographs? No OSHA Regulated? No
12. Ecological Information
Ecological Information: Runoff from fire control or dilution water may cause pollution.
13. Disposal Considerations
Waste Disposal Method: Dispose in accordance with local, state and federal regulations.
14. Transport Information
LAND TRANSPORT (US DOT)
DOT Proper Shipping Name: No data available.
Additional Transport Information: Transport in accordance with local, state, and federal regulations.
15. Regulatory Information
US EPA SARA Title III
U-73122
Hazardous Components (Chemical Name)
112648-68-7
CAS #
No
Sec.302 (EHS)
No
Sec.304 RQ
No
Sec.313 (TRI)
No
Sec.110
1.
US EPA CAA, CWA, TSCA
U-73122
Hazardous Components (Chemical Name)
112648-68-7
CAS #
No
EPA CAA
No
EPA CWA NPDES
No
EPA TSCA
No
CA PROP 65
1.
SARA (Superfund Amendments and
Reauthorization Act of 1986) Lists:
Sec.302: EPA SARA Title III Section 302 Extremely Hazardous Chemical with TPQ. * indicates 10000 LB TPQ if not volatile.
Sec.304: EPA SARA Title III Section 304: CERCLA Reportable + Sec.302 with Reportable Quantity. ** indicates statutory RQ.
Sec.313: EPA SARA Title III Section 313 Toxic Release Inventory. Note: -Cat indicates a member of a chemical category.
Sec.110: EPA SARA 110 Superfund Site Priority Contaminant List
TSCA (Toxic Substances Control
Act) Lists:
5A(2): Chemical Subject to Significant New Rules (SNURS)
6A: Commercial Chemical Control Rules
8A: Toxic Substances Subject To Information Rules on Production
8A CAIR: Comprehensive Assessment Information Rules - (CAIR)
8A PAIR: Preliminary Assessment Information Rules - (PAIR)
8C: Records of Allegations of Significant Adverse Reactions
8D: Health and Safety Data Reporting Rules
8D TERM: Health and Safety Data Reporting Rule Terminations
Other Important Lists:
CWA NPDES: EPA Clean Water Act NPDES Permit Chemical
CAA HAP: EPA Clean Air Act Hazardous Air Pollutant
CAA ODC: EPA Clean Air Act Ozone Depleting Chemical (1=CFC, 2=HCFC)
ANSI Z400.1 Format
08/07/2005 Revision:
08/07/2005 Printed:
4 Page:
U-73122
MATERIAL SAFETY DATA SHEET
07/30/2004 Supercedes Revision:
CA PROP 65: California Proposition 65
16. Other Information
For research use only, not for human or veterinary clinical use.
DISCLAIMER: This information is believed to be accurate and represents the best information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should
make their own investigations to determine the suitability of the information for their particular purposes.
Company Policy or Disclaimer
ANSI Z400.1 Format