SIGMA-ALDRICH 
Material Safety Data Sheet 
Date Printed: 09/OCT/2003 
Date Updated: 09/APR/2002 
Version 1.0 
According to 91/155/EEC 
1 - Product and Company Information 
Product Name VASOACTIVE INTESTINAL PEPTIDE PORCINE 
Product Number V3628 
Company Sigma-Aldrich Chemie GmbH 
Riedstrasse 2 
89555 Steinheim 
Germany 
Technical Phone # 49-89-6513(0)-1444 
Fax 49-7329-97-2319 
Emergency Phone # 49 7329 97 2323 
2 - Composition/Information on Ingredients 
Product Name CAS # EC no 
VASOACTIVE INTESTINAL PEPTIDE 40077-57-4 None 
PORCINE 
Formula C147H238N44O42S 
Molecular Weight 3,325 AMU 
3 - Hazards Identification 
4 - First Aid Measures 
AFTER INHALATION 
If inhaled, remove to fresh air. If breathing becomes difficult, 
call a physician. 
AFTER SKIN CONTACT 
In case of skin contact, flush with copious amounts of water for 
at least 15 minutes. Remove contaminated clothing and shoes. 
Call a physician. 
AFTER EYE CONTACT 
In case of contact with eyes, flush with copious amounts of 
water for at least 15 minutes. Assure adequate flushing by 
separating the eyelids with fingers. Call a physician. 
AFTER INGESTION 
If swallowed, wash out mouth with water provided person is 
conscious. Call a physician. 
5 - Fire Fighting Measures 
EXTINGUISHING MEDIA 
Suitable: Carbon dioxide, dry chemical powder, or appropriate 
foam. Water spray. 
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing 
to prevent contact with skin and eyes. 
6 - Accidental Release Measures 
PROCEDURE(S) OF PERSONAL PRECAUTION(S) 
Wear respirator, chemical safety goggles, rubber boots, and 
heavy rubber gloves. 
METHODS FOR CLEANING UP 
Sweep up, place in a bag and hold for waste disposal. Ventilate 
area and wash spill site after material pickup is complete. 
7 - Handling and Storage 
STORAGE 
Store at -20°C 
8 - Exposure Controls / Personal Protection 
ENGINEERING CONTROLS 
Mechanical exhaust. 
GENERAL HYGIENE MEASURES 
Wash thoroughly after handling. 
PERSONAL PROTECTIVE EQUIPMENT 
Respiratory Protection: Government approved respirator. 
Hand Protection: Compatible chemical-resistant gloves. 
Eye Protection: Chemical safety goggles. 
9 - Physical and Chemical Properties 
Appearance Color: White 
Form: Powder 
Property Value At Temperature or Pressure 
pH N/A 
BP/BP Range N/A 
MP/MP Range N/A 
Flash Point N/A 
Flammability N/A 
Autoignition Temp N/A 
Oxidizing Properties N/A 
Explosive Properties N/A 
Explosion Limits N/A 
Vapor Pressure N/A 
Partition Coefficient N/A 
Viscosity N/A 
Vapor Density N/A 
Saturated Vapor Conc. N/A 
Evaporation Rate N/A 
Bulk Density N/A 
Decomposition Temp. N/A 
Solvent Content N/A 
Water Content N/A 
Surface Tension N/A 
Conductivity N/A 
Miscellaneous Data N/A 
Solubility Solubility in Water:1 mg/ml H2O clear, 
colorless 
SIGMA - V3628 www.sigma-aldrich.com Page 2
10 - Stability and Reactivity 
STABILITY 
Stable: Stable. 
Materials to Avoid: Trypsin, chymotrypsin, pepsin. 
HAZARDOUS DECOMPOSITION PRODUCTS 
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, 
Nitrogen oxides, Sulfur oxides. 
HAZARDOUS POLYMERIZATION 
Hazardous Polymerization: Will not occur 
11 - Toxicological Information 
SIGNS AND SYMPTOMS OF EXPOSURE 
Vasoactive intestinal peptide and some fragments of vasoactive 
intestinal peptide may cause systemic vasodilation, hypotension 
and respiratory effects. To the best of our knowledge, the 
chemical, physical, and toxicological properties have not been 
thoroughly investigated. 
ROUTE OF EXPOSURE 
Skin Contact: May cause skin irritation. 
Eye Contact: May cause eye irritation. 
Inhalation: Material may be irritating to mucous membranes and 
upper respiratory tract. 
Multiple Routes: May be harmful by inhalation, ingestion, or 
skin absorption. 
TARGET ORGAN INFORMATION 
Nerves. Smooth muscle. Vascular system. 
12 - Ecological Information 
No data available. 
13 - Disposal Considerations 
SUBSTANCE DISPOSAL 
Dissolve or mix the material with a combustible solvent and burn 
in a chemical incinerator equipped with an afterburner and 
scrubber. Observe all federal, state, and local environmental 
regulations. 
14 - Transport Information 
RID/ADR 
Non-hazardous for road transport. 
IMDG 
Non-hazardous for sea transport. 
IATA 
Non-hazardous for air transport. 
15 - Regulatory Information 
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES 
S-PHRASES: 22 24/25 
Do not breathe dust. Avoid contact with skin and eyes. 
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16 - Other Information 
WARRANTY 
The above information is believed to be correct but does not 
purport to be all inclusive and shall be used only as a guide. 
Sigma-Aldrich Inc., shall not be held liable for any damage 
resulting from handling or from contact with the above product. 
See reverse side of invoice or packing slip for additional terms 
and conditions of sale. Copyright 2003 Sigma-Aldrich Co. License 
granted to make unlimited paper copies for internal use only. 
DISCLAIMER 
For R&D use only. Not for drug, household or other uses. 
SIGMA - V3628 www.sigma-aldrich.com Page 4