Revision Date: 18-Oct-2007 Material Safety Data Sheet 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Product code LC2670 Product name Novex® Zymogram Renaturing Buffer (10X) Company/Undertaking Identification 2. COMPOSITION/INFORMATION ON INGREDIENTS Hazardous/Non-hazardous Components Chemical Name CAS-No Weight % Triton X-100 9002-93-1 15-40 The product contains no substances which at their given concentration, are considered to be hazardous to health 3. HAZARDS IDENTIFICATION ____________________________________________________________________________________________ Page 1 / 5 Emergency Overview The product contains no substances which at their given concentration, are considered to be hazardous to health INVITROGEN CORPORATON 1600 FARADAY AVENUE PO BOX 6482 CARLSBAD, CA 92008 760-603-7200 INVITROGEN CORPORATION 2270 INDUSTRIAL STREET BURLINGTON, ONT CANADA L7P 1A1 800-263-6236 GIBCO PRODUCTS INVITROGEN CORPORATION 3175 STALEY ROAD P.O. BOX 68 GRAND ISLAND, NY 14072 716-774-6700 Form Liquid 3. HAZARDS IDENTIFICATION Eyes No information available Skin No information available Inhalation No information available Ingestion No information available Specific effects Carcinogenic effects No information available Mutagenic effects No information available Reproductive toxicity No information available Sensitization No information available Target Organ Effects No information available HMIS 4. FIRST AID MEASURES Skin contact Wash off immediately with plenty of water Eye contact Rinse thoroughly with plenty of water, also under the eyelids. Ingestion Never give anything by mouth to an unconscious person Inhalation Move to fresh air Notes to physician Treat symptomatically. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Dry chemical Special protective equipment for firefighters Wear self-contained breathing apparatus and protective suit 6. ACCIDENTAL RELEASE MEASURES Personal precautions Use personal protective equipment. Avoid contact with the skin and the eyes. Methods for cleaning up Soak up with inert absorbent material. 7. HANDLING AND STORAGE Handling No special handling advice required Storage Keep in properly labelled containers 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Occupational exposure controls Exposure limits Chemical Name OSHA PEL (TWA) OSHA PEL (Ceiling) ACGIH OEL (TWA) ACGIH OEL (STEL) Triton X-100 - - - - Engineering measures Ensure adequate ventilation, especially in confined areas ____________________________________________________________________________________________ Page 2 / 5 Principle Routes of Exposure/ Potential Health effects Flammability 0 Health Reactivity 0 0 Personal protective equipment Respiratory protection In case of insufficient ventilation wear suitable respiratory equipment Hand protection Protective gloves Eye protection Safety glasses with side-shields Skin and body protection Lightweight protective clothing. Hygiene measures Handle in accordance with good industrial hygiene and safety practice Environmental exposure controls Prevent product from entering drains. 9. PHYSICAL AND CHEMICAL PROPERTIES General Information Form Liquid Important Health Safety and Environmental Information Oxidizing properties No information available Water solubility soluble 10. STABILITY AND REACTIVITY Stability Stable. Materials to avoid No information available Hazardous decomposition products No information available Polymerization Hazardous polymerisation does not occur. 11. TOXICOLOGICAL INFORMATION Acute toxicity Chemical Name LD50 (oral,rat/mouse) LD50 (dermal,rat/rabbit) LC50 (inhalation,rat/mouse) Triton X-100 1800 mg/kg (Rat) No data available No data available Principle Routes of Exposure/ Potential Health effects Eyes No information available Skin No information available Inhalation No information available Ingestion No information available Specific effects Carcinogenic effects No information available Mutagenic effects No information available Reproductive toxicity No information available Sensitization No information available Target Organ Effects No information available ____________________________________________________________________________________________ Page 3 / 5 Autoignition temperature °C No data available °F No data available Boiling point/range Melting point/range °C No data available °F No data available °C No data available Flash point °C No data available °F No data available °F No data available 12. ECOLOGICAL INFORMATION Ecotoxicity effects No information available. Mobility No information available. Biodegradation Inherently biodegradable. Bioaccumulation Does not bioaccumulate. 13. DISPOSAL CONSIDERATIONS Dispose of in accordance with local regulations 14. TRANSPORT INFORMATION IATA Proper shipping name Not classified as dangerous in the meaning of transport regulations Hazard Class No information available Subsidiary Class No information available Packing group No information available UN-No No information available 15. REGULATORY INFORMATION International Inventories Chemical Name TSCA PICCS ENCS DSL NDSL AICS Triton X-100 Listed Listed - Listed - Listed U.S. Federal Regulations SARA 313 This product is not regulated by SARA. Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product does not contains HAPs. U.S. State Regulations Chemical Name Massachusetts - RTK New Jersey - RTK Pennsylvania - RTK Illinois - RTK Rhode Island - RTK Triton X-100 - - - - - California Proposition 65 This product does not contain chemicals listed under Proposition 65 WHMIS hazard class: Non-controlled This product has been classified according to the hazard criteria of the CPR and the MSDS contains all of the information required by the CPR ____________________________________________________________________________________________ Page 4 / 5 16. OTHER INFORMATION This material is sold for research and development purposes only. It is not for any human or animal therapeutic or clinical diagnostic use. It is not intended for food, drug, household, agricultural, or cosmetic use. An individual technically qualified to handle potentially hazardous chemicals must supervise the use of this material. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may be present unknown hazards and should be used with caution. Since Invitrogen Corporation cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRANTY, EXPRESS OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTCULAR PURPOSE. End of Safety Data Sheet ____________________________________________________________________________________________ Page 5 / 5