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MSDS Safety Information 
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NAME:  ACCESS HLH REAGENT

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Page 1 of 16
Kit MSDS
Doc. ID: 3351075:
Rev. AA
Product Information
Product Name hLH
Part Number 33510
Doc. ID 3351075
AA
Issued (day/month/year) 02/10/1998
Series Name: ACCESSâ
Components
Description
hLH (Compartment R1a)
hLH (Compartment R1b)
hLH (Compartment R1c)
Transport Information
Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG.
ă1998 Beckman Instruments, Inc.
Global MSDS – English
Page 2 of 16
MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Product Name hLH
(Compartment R1a)
Part Number Component of P/N 33510
hLH
Doc. ID 3351075
AA
Issued (day/month/year) 02/10/1998
Series Name ACCESSâ
Manufacturer Beckman Instruments, Inc.
2500 Harbor Blvd.
Fullerton, CA 928343100,
U.S.A.
Distributor and
Emergency Phone No. % Refer to attached list, Document ID: 472050, for local distributor and
emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Tris(hydroxymethyl)aminomethane 77861
<5.0 No Yes Exempt
See Section 15 Regulatory Information for additional information on ingredient hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Reddishbrown;
Opaque; Liquid; Odorless
Nonflammable aqueous solution.
Contains animal material which may have come in contact with human material.
Skin, eye and respiratory tract irritant.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health
Effects Summary
Exposure may result in irritation of skin, eyes, and mucous membranes.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard
Classifications
EU:
Not applicable
WHMIS:
Exempt
US OSHA:
Hazardous
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product is splashed in eyes, wash eyes under gently running water for
15 minutes or longer, making sure that the eyelids are held open. Obtain
medical attention.
hLH Doc. ID: 3351075
AA Page 3 of 16
hLH (Compartment R1a)
Section 4 First Aid Measures (Continued)
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15
minutes. Then gently wash skin with soap and water; rinse well. If product
contacted broken skin, soak the wound area with a 1:10 dilution of fresh
household bleach for 10 minutes. Rinse with water to remove residual bleach.
(Remove contaminated clothing and disinfect with a 1:10 dilution of fresh
household bleach.) Obtain medical attention.
Ingestion If ingested, wash out mouth with water. Call a physician.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and
Explosion Hazards
No special hazards determined.
Hazardous Combustion
Products
Due to the composition and volume of this product, combustion products
generated from it are not expected to present a significant hazard.
Protective Equipment
for Firefighters
Selfcontained
breathing apparatus is recommended for firefighters.
Section 6 Accidential Release Measures
Personal Precautions Use universal precautions during clean up procedures.
Spill and Leak
Procedures
As a precautionary measure, treat spilled material with a 1:10 bleach/water
solution. Absorb liquid and place in container suitable for disposal. Avoid
generation of aerosols during clean up. Comply with applicable waste
disposal regulations.
Environmental
Precautions
Contain spill to prevent migration.
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious
diseases. Universal precautions should be followed when using this product.
Recommended Storage
Conditions
Keep away from incompatible material.
To maintain efficacy, store according to the instructions in the product
labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK: None established
hLH Doc. ID: 3351075
AA Page 4 of 16
hLH (Compartment R1a)
Section 8 Exposure Controls and Personal Protection (Continued)
Engineering Controls Use in well ventilated area.
Respiratory Protection Under normal conditions, the use of this product should not require
respiratory protection. If overexposure should occur and ventilation is not
adequate to maintain airborne concentrations at acceptable levels, the use
of respiratory protection should be evaluated by a qualified professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent
skin contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Reddishbrown
Transparency Opaque
Odor Odorless
Odor Threshold Not applicable
pH 7.4
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.030 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Coefficient of Water/Oil
Distribution
Not available
Percent Volatiles Not available
Solubility
Water Matrix is miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous
Incompatibilities
Metals and metallic compounds
Strong Oxidizers
Strong acids
Sodium azide forms explosive compounds with heavy metals. Repeated
contact of low concentrations of azide with lead and copper commonly found
in plumbing drains may result in the build up of shock sensitive compounds.
Hazardous
Decomposition Products
When stored as labeled, no known hazardous decomposition products are
formed during the shelflife
of this product.
Conditions to Avoid Keep away from incompatible material.
hLH Doc. ID: 3351075
AA Page 5 of 16
hLH (Compartment R1a)
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Tris(hydroxymethyl)aminomethane
Oral LD50 Rat: 5900 mg/kg
Primary Routes
of Exposure
Common routes of entry include inhalation, ingestion and eye/skin contact.
Specific paths of concern for potentially infectious materials are skin puncture,
contact with broken skin, contact with mucous membranes and inhalation of
aerosolized material.
Potential Effects of
Acute Exposure
Exposure to TRIS may result in irritation of skin, eyes and mucous
membrane. Eye contact may result in redness, pain and corneal injury.
Inhalation may result in chest pain and tightness, coughing, and difficult
breathing. Ingestion may cause gastrointestinal irritation with burns to mouth
and stomach, and large doses may cause weakness, collapse and death in
laboratory animals.
This product contains materials of animal origin, some of which may have
come into contact with human material during processing. The product
should be considered as potentially capable of transmitting infectious
diseases.
Potential Effects of
Chronic Exposure
Prolonged or repeated exposure to TRIS by skin contact may result in
dermititis. Eye contact may cause conjunctivitis.
Symptoms of
Overexposure
Symptoms of overexposure may include: throat irritation and coughing; dry,
red, cracked skin; red irritated eyes; headache, drowsiness, dizziness, stupor;
convulsions and coma.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC,
NTP, OSHA or 67/548/EEC Annex I.
Other Effects None identified.
Conditions Aggravated
by Exposure
None identified.
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging
in compliance with federal, state and local regulations. If unsure of the
applicable requirements, contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain
lines. See NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG.
hLH Doc. ID: 3351075
AA Page 6 of 16
hLH (Compartment R1a)
Section 15 Regulatory Information
US Federal and State
Regulations
SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of
SARA.
Zinc Chloride is subject to reporting requirements of Section 313, Title III of
SARA.
CERCLA RG’s,
40 CFR 302.4
Zinc Chloride is listed.
Sodium Azide is listed.
California Proposition 65 No ingredients listed
Massachusetts MSL Zinc Chloride is listed.
Sodium Azide is listed.
Magnesium Chloride is listed.
New Jersey Dept. of
Health RTK List
Zinc Chloride is listed.
Sodium Azide is listed.
Magnesium Chloride is listed.
Pennsylvania RTK Zinc Chloride is listed.
Sodium Azide is listed.
Magnesium Chloride is listed.
EU
Dangerous Ingredients None
Canada
This product is exempt from WHMIS label and MSDS requirements.
PIN: Not applicable
Ingredients on Ingredient
Disclosure List:
Zinc Chloride
Sodium Azide
Ingredients with unknown
toxicological properties:
None
Section 16 Other Information
For further information, please contact your local Beckman representative.
WHILE BECKMAN INSTRUMENTS, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN MAKES NO WARRANTY OR REPRESENTATION
AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER
THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 7 of 16
MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Product Name hLH
(Compartment R1b)
Part Number Component of P/N 33510
hLH
Doc. ID 3351075
AA
Issued (day/month/year) 02/10/1998
Series Name ACCESSâ
Manufacturer Beckman Instruments, Inc.
2500 Harbor Blvd.
Fullerton, CA 928343100,
U.S.A.
Distributor and
Emergency Phone No. % Refer to attached list, Document ID: 472050, for local distributor and
emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Tris(hydroxymethyl)aminomethane 77861
<5.0 No Yes Exempt
See Section 15 Regulatory Information for additional information on ingredient hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Colorless; Clear; Liquid; Odorless
Nonflammable aqueous solution.
Skin, eye and respiratory tract irritant.
Contains material of animal origin.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health
Effects Summary
Exposure may result in irritation of skin, eyes, and mucous membranes.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard
Classifications
EU:
Not applicable
WHMIS:
Exempt
US OSHA:
Hazardous
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product is splashed in eyes, wash eyes under gently running water for
15 minutes or longer, making sure that the eyelids are held open. Obtain
medical attention.
hLH Doc. ID: 3351075
AA Page 8 of 16
hLH (Compartment R1b)
Section 4 First Aid Measures (Continued)
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15
minutes. Then gently wash skin with soap and water; rinse well. If product
contacted broken skin, soak the wound area with a 1:10 dilution of fresh
household bleach for 10 minutes. Rinse with water to remove residual bleach.
(Remove contaminated clothing and disinfect with a 1:10 dilution of fresh
household bleach.) Obtain medical attention.
Ingestion If ingested, wash out mouth with water. Call a physician.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and
Explosion Hazards
No special hazards determined.
Hazardous Combustion
Products
Due to the composition and volume of this product, combustion products
generated from it are not expected to present a significant hazard.
Protective Equipment
for Firefighters
Selfcontained
breathing apparatus is recommended for firefighters.
Section 6 Accidential Release Measures
Personal Precautions Use universal precautions during clean up procedures.
Spill and Leak
Procedures
As a precautionary measure, treat spilled material with a 1:10 bleach/water
solution. Absorb liquid and place in container suitable for disposal. Avoid
generation of aerosols during clean up. Comply with applicable waste
disposal regulations.
Environmental
Precautions
Contain spill to prevent migration.
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious
diseases. Universal precautions should be followed when using this product.
Recommended Storage
Conditions
Keep away from incompatible material.
To maintain efficacy, store according to the instructions in the product
labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK: None established
hLH Doc. ID: 3351075
AA Page 9 of 16
hLH (Compartment R1b)
Section 8 Exposure Controls and Personal Protection (Continued)
Engineering Controls Use in well ventilated area.
Respiratory Protection Under normal conditions, the use of this product should not require
respiratory protection. If overexposure should occur and ventilation is not
adequate to maintain airborne concentrations at acceptable levels, the use
of respiratory protection should be evaluated by a qualified professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent
skin contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Clear
Odor Odorless
Odor Threshold Not applicable
pH 8.05
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.006 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Coefficient of Water/Oil
Distribution
Not available
Percent Volatiles Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous
Incompatibilities
Metals and metallic compounds
Strong Oxidizers
Strong acids
Sodium azide forms explosive compounds with heavy metals. Repeated
contact of low concentrations of azide with lead and copper commonly found
in plumbing drains may result in the build up of shock sensitive compounds.
Hazardous
Decomposition Products
When stored as labeled, no known hazardous decomposition products are
formed during the shelflife
of this product.
Conditions to Avoid Keep away from incompatible material.
hLH Doc. ID: 3351075
AA Page 10 of 16
hLH (Compartment R1b)
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Tris(hydroxymethyl)aminomethane
Oral LD50 Rat: 5900 mg/kg
Primary Routes
of Exposure
Common routes of entry include inhalation, ingestion and eye/skin contact.
Specific paths of concern for potentially infectious materials are skin puncture,
contact with broken skin, contact with mucous membranes and inhalation of
aerosolized material.
Potential Effects of
Acute Exposure
Exposure to TRIS may result in irritation of skin, eyes and mucous
membrane. Eye contact may result in redness, pain and corneal injury.
Inhalation may result in chest pain and tightness, coughing, and difficult
breathing. Ingestion may cause gastrointestinal irritation with burns to mouth
and stomach, and large doses may cause weakness, collapse and death in
laboratory animals.
This product contains material of animal origin and should be considered as
potentially capable of transmitting infectious diseases.
Potential Effects of
Chronic Exposure
Prolonged or repeated exposure to TRIS by skin contact may result in
dermititis. Eye contact may cause conjunctivitis.
Symptoms of
Overexposure
Symptoms of overexposure may include: throat irritation and coughing; dry,
red, cracked skin; red irritated eyes; headache, drowsiness, dizziness, stupor;
convulsions and coma.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC,
NTP, OSHA or 67/548/EEC Annex I.
Other Effects None identified.
Conditions Aggravated
by Exposure
None identified.
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging
in compliance with federal, state and local regulations. If unsure of the
applicable requirements, contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain
lines. See NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG.
hLH Doc. ID: 3351075
AA Page 11 of 16
hLH (Compartment R1b)
Section 15 Regulatory Information
US Federal and State
Regulations
SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of
SARA.
Zinc Chloride is subject to reporting requirements of Section 313, Title III of
SARA.
CERCLA RG’s,
40 CFR 302.4
Zinc Chloride is listed.
Sodium Azide is listed.
California Proposition 65 No ingredients listed
Massachusetts MSL Zinc Chloride is listed.
Sodium Azide is listed.
Magnesium Chloride is listed.
New Jersey Dept. of
Health RTK List
Zinc Chloride is listed.
Sodium Azide is listed.
Magnesium Chloride is listed.
Pennsylvania RTK Zinc Chloride is listed.
Sodium Azide is listed.
Magnesium Chloride is listed.
EU
Dangerous Ingredients None
Canada
This product is exempt from WHMIS label and MSDS requirements.
PIN: Not applicable
Ingredients on Ingredient
Disclosure List:
Zinc Chloride
Sodium Azide
Ingredients with unknown
toxicological properties:
None
Section 16 Other Information
For further information, please contact your local Beckman representative.
WHILE BECKMAN INSTRUMENTS, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN MAKES NO WARRANTY OR REPRESENTATION
AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER
THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 12 of 16
MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Product Name hLH
(Compartment R1c)
Part Number Component of P/N 33510
hLH
Doc. ID 3351075
AA
Issued (day/month/year) 02/10/1998
Series Name ACCESSâ
Manufacturer Beckman Instruments, Inc.
2500 Harbor Blvd.
Fullerton, CA 928343100,
U.S.A.
Distributor and
Emergency Phone No. % Refer to attached list, Document ID: 472050, for local distributor and
emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Tris(hydroxymethyl)aminomethane 77861
<5.0 No Yes Exempt
See Section 15 Regulatory Information for additional information on ingredient hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Colorless; Clear; Liquid; Odorless
Nonflammable aqueous solution.
Contains animal material which may have come in contact with human material.
Skin, eye and respiratory tract irritant.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health
Effects Summary
Exposure may result in irritation of skin, eyes, and mucous membranes.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard
Classifications
EU:
Not applicable
WHMIS:
Exempt
US OSHA:
Hazardous
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product is splashed in eyes, wash eyes under gently running water for
15 minutes or longer, making sure that the eyelids are held open. Obtain
medical attention.
hLH Doc. ID: 3351075
AA Page 13 of 16
hLH (Compartment R1c)
Section 4 First Aid Measures (Continued)
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15
minutes. Then gently wash skin with soap and water; rinse well. If product
contacted broken skin, soak the wound area with a 1:10 dilution of fresh
household bleach for 10 minutes. Rinse with water to remove residual bleach.
(Remove contaminated clothing and disinfect with a 1:10 dilution of fresh
household bleach.) Obtain medical attention.
Ingestion If ingested, wash out mouth with water. Call a physician.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and
Explosion Hazards
Combustion products may contain minute amounts of mercury.
Hazardous Combustion
Products
Due to the composition and volume of this product, combustion products
generated from it are not expected to present a significant hazard.
Protective Equipment
for Firefighters
Selfcontained
breathing apparatus is recommended for firefighters.
Section 6 Accidential Release Measures
Personal Precautions Use universal precautions during clean up procedures.
Spill and Leak
Procedures
As a precautionary measure, treat spilled material with a 1:10 bleach/water
solution. Absorb liquid and place in container suitable for disposal. Avoid
generation of aerosols during clean up. Comply with applicable waste
disposal regulations.
Environmental
Precautions
Contain spill to prevent migration.
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious
diseases. Universal precautions should be followed when using this product.
Recommended Storage
Conditions
Keep away from incompatible material.
To maintain efficacy, store according to the instructions in the product
labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK: None established
hLH Doc. ID: 3351075
AA Page 14 of 16
hLH (Compartment R1c)
Section 8 Exposure Controls and Personal Protection (Continued)
Engineering Controls Use in well ventilated area.
Respiratory Protection Under normal conditions, the use of this product should not require
respiratory protection. If overexposure should occur and ventilation is not
adequate to maintain airborne concentrations at acceptable levels, the use
of respiratory protection should be evaluated by a qualified professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent
skin contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Clear
Odor Odorless
Odor Threshold Not applicable
pH 8.2
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.015 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Coefficient of Water/Oil
Distribution
Not available
Percent Volatiles Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous
Incompatibilities
Metals and metallic compounds
Strong Oxidizers
Strong acids
Sodium azide forms explosive compounds with heavy metals. Repeated
contact of low concentrations of azide with lead and copper commonly found
in plumbing drains may result in the build up of shock sensitive compounds.
Hazardous
Decomposition Products
When stored as labeled, no known hazardous decomposition products are
formed during the shelflife
of this product.
Conditions to Avoid Keep away from incompatible material.
hLH Doc. ID: 3351075
AA Page 15 of 16
hLH (Compartment R1c)
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Tris(hydroxymethyl)aminomethane
Oral LD50 Rat: 5900 mg/kg
Primary Routes
of Exposure
Common routes of entry include inhalation, ingestion and eye/skin contact.
Specific paths of concern for potentially infectious materials are skin puncture,
contact with broken skin, contact with mucous membranes and inhalation of
aerosolized material.
Potential Effects of
Acute Exposure
Exposure to TRIS may result in irritation of skin, eyes and mucous
membrane. Eye contact may result in redness, pain and corneal injury.
Inhalation may result in chest pain and tightness, coughing, and difficult
breathing. Ingestion may cause gastrointestinal irritation with burns to mouth
and stomach, and large doses may cause weakness, collapse and death in
laboratory animals.
This product contains materials of animal origin, some of which may have
come into contact with human material during processing. The product
should be considered as potentially capable of transmitting infectious
diseases.
Potential Effects of
Chronic Exposure
Prolonged or repeated exposure to TRIS by skin contact may result in
dermititis. Eye contact may cause conjunctivitis.
Symptoms of
Overexposure
Symptoms of overexposure may include: throat irritation and coughing; dry,
red, cracked skin; red irritated eyes; headache, drowsiness, dizziness, stupor;
convulsions and coma.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC,
NTP, OSHA or 67/548/EEC Annex I.
Other Effects None identified.
Conditions Aggravated
by Exposure
None identified.
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging
in compliance with federal, state and local regulations. If unsure of the
applicable requirements, contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain
lines. See NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
This product contains a low level (<0.05%) of Thimerosal. Specific federal,
state, and local regulations for disposal of mercury compounds may apply.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG.
hLH Doc. ID: 3351075
AA Page 16 of 16
hLH (Compartment R1c)
Section 15 Regulatory Information
US Federal and State
Regulations
SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of
SARA.
Thimerosal is subject to reporting requirements of Section 313, Title III of SARA.
Zinc Chloride is subject to reporting requirements of Section 313, Title III of
SARA.
CERCLA RG’s,
40 CFR 302.4
Zinc Chloride is listed.
Sodium Azide is listed.
Thimerosal is listed.
California Proposition 65 Thimerosal has been identified by the State of California to cause reproductive
harm. The State of California has adopted a regulation which requires a warning
be given to individuals who may be exposed to chemicals identified by the State
to cause cancer or reproductive harm. Accordingly, Beckman Coulter advises
you of the following warning:
WARNING: This product contains a chemical known to the State of California to
cause reproductive harm.
Massachusetts MSL Zinc Chloride is listed.
Sodium Azide is listed.
Thimerosal is listed.
Magnesium Chloride is listed.
Magnesium Chloride, Hexahydrate is listed.
New Jersey Dept. of
Health RTK List
Zinc Chloride is listed.
Sodium Azide is listed.
Thimerosal is listed.
Magnesium Chloride is listed.
Magnesium Chloride, Hexahydrate is listed.
Pennsylvania RTK Zinc Chloride is listed.
Sodium Azide is listed.
Thimerosal is listed.
Magnesium Chloride is listed.
Magnesium Chloride, Hexahydrate is listed.
EU
Dangerous Ingredients None
Canada
This product is exempt from WHMIS label and MSDS requirements.
PIN: Not applicable
Ingredients on Ingredient
Disclosure List:
Thimerosal
Zinc Chloride
Sodium Azide
Ingredients with unknown
toxicological properties:
None
Section 16 Other Information
For further information, please contact your local Beckman representative.
WHILE BECKMAN INSTRUMENTS, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN MAKES NO WARRANTY OR REPRESENTATION
AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER
THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.