======================================================= MSDS Safety Information ======================================================= NAME: ACETET FOR ANALYSIS ======================================================= In USA: In Europe: Thermo Fisher Scientific Perbio Science P.O. Box 117 Industriezone III Rockford, IL 61105 Industrielaan 27 USA 9320 Erembodegem-Aalst 815.968.0747 or Belgium 1.800.874.3723 Tel:+32 53 83 44 04 Fax:+32 53 83 76 38 Conforms to 93/112/EC and ISO 11014-1 Material Safety Data Sheet Antibodies/Proteins in Potassium Acetate R20001 1900729 Product Name Supplier Manufacturer Product no. In case of emergency Section 1. Chemical Product and Company Identification Responsible Name MSDS Administrator Use of the substance/preparation Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. Eng CHEMTREC: 800.424.9300 OUTSIDE US: 703.527.3887 Print date 8/24/2007 Validation date 8/24/2007 MSDS# 6412 Pierce 3747 N. Meridian Road P.O. Box 117 Rockford, IL 61105 USA 815.968.0747 or 1.800.874.3723 (815)968-7316 fax www.thermo.com Substance/preparation : Preparation Section 2. Composition, Information on Ingredients No hazardous ingredient according to 29 CFR 1910.1200 Hazard Communication Standard (USA) and Directives 1999/45/EC-2001/59/EC (EU) Physical/chemical hazards Human health hazards Environmental hazards Not applicable. Not applicable. Not applicable. Eye contact. Inhalation. Ingestion. Emergency overview Medical conditions aggravated by overexposure Repeated or prolonged exposure is not known to aggravate medical condition. Over-exposure signs/symptoms Not available. Section 3. Hazards identification Routes of entry Carcinogenic effects See toxicological Information (section 11) CARCINOGENIC EFFECTS: Classified None. by OSHA, None. by NIOSH [Potassium Acetate]. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. Review the most current and approved institutional guideline, protocol, standard operating procedure(s) and MSDS(s) for the proper handling of institutional materials/equipment associated with the use of this product. No specific hazard. Classification Not classified. United States Europe Potential acute health effects No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. Eyes Skin Inhalation Ingestion Potential chronic health effects Continued on Next Page Antibodies/Proteins in Potassium Acetate Page: 2/6 Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if symptoms appear. Skin contact Ingestion In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs. In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Not available. Not available. Skin contact Irritation of the product in case of skin contact: Not available. Sensitization of the product: Not available. Eye contact Not available. Inhalation Aggravating conditions Repeated or prolonged exposure is not known to aggravate medical condition. First-Aid measures If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention. Notes to physician Not available. Protection of first-aiders Not available. Ingestion Effects and symptoms Inhalation Eye contact Section 4. First aid measures Hazardous thermal decomposition products Not applicable. Non-flammable. Not applicable. Use an extinguishing agent suitable for surrounding fires. Not applicable. Section 5. Fire fighting measures Flammability of the product Flash Points Fire hazards in presence of various substances Fire fighting media and instructions Protective clothing (fire) Not applicable. Absorb with an inert material and put the spilled material in an appropriate waste disposal. Neutralize the residue with a dilute solution of acetic acid. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 6. Accidental release measures Small spill and leak Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. If necessary: Neutralize the residue with a dilute solution of acetic acid. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Environmental precautions and clean-up methods Personal precautions Safety glasses. Lab coat. Keep container tightly closed. Keep container in a cool, well-ventilated area. Wash thoroughly after handling. Section 7. Handling and storage Handling Storage Suitable / Not suitable Packaging materials Use original container. Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. Continued on Next Page Antibodies/Proteins in Potassium Acetate Page: 3/6 United States Ingredient Name Occupational Exposure Limits Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective occupational exposure limits. Section 8. Exposure Controls, Personal Protection Exposure Limit Values Personal Protection Eyes Body Protective Clothing (Pictograms) Safety glasses. Lab coat. The lowest known value is 100°C (212°F) (water). Liquid. Basic. May start to solidify at 0°C (32°F) based on data for: water. The only known value is 1 (Water = 1) (water). The highest known value is 0.62 (Air = 1) (water). The highest known value is 2.3 kPa (17.5 mm Hg) (at 20°C) (water). See solubility in water, methanol, acetone. Easily soluble in cold water, hot water, methanol, acetone. The lowest known value is 374.2°C (705.6°F) (water). Not applicable. Not available. Not available. Not available. Boiling/condensation point Melting/freezing point 0.36 (water) compared to (n-BUTYL ACETATE=1) Dynamic: The highest known value is 1 cP (water) Physical State Molecular weight pH Critical temperature Specific Gravity Vapor pressure Vapor density Evaporation rate Viscosity Dispersion properties Solubility Odor Taste Color Section 9. Physical and chemical properties The product is stable. Not available. Will not occur. Not available. Section 10. Stability and reactivity Stability and Reactivity Conditions to avoid Materials to avoid Hazardous polymerization Hazardous Decomposition Products Not available. Continued on Next Page Antibodies/Proteins in Potassium Acetate Page: 4/6 water: ORAL (LD50): Acute: >90000 mg/kg [ Rat]. Potassium Acetate: ORAL (LD50): Acute: 3250 mg/kg [Rat]. No specific information is available in our database regarding the other toxic effects of this material for humans. CARCINOGENIC EFFECTS: Classified None. by OSHA, None. by NIOSH [Potassium Acetate]. Not available. Not available. Not available. Section 11. Toxicological information Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Special Remarks on Toxicity to Animals Special Remarks on Chronic Effects on Humans Special Remarks on Other Toxic Effects on Humans Skin Ingestion Inhalation No known significant effects or critical hazards. No known significant effects or critical hazards. No known significant effects or critical hazards. Over-exposure signs/symptoms Carcinogenicity No known significant effects or critical hazards. Mutagenicity No known significant effects or critical hazards. Reproductive toxicity No known significant effects or critical hazards. Ecotoxicity Not available. Mobility Germany water class Not available. Not available. Not available. Persistence/degradability Bioaccumulative potential VCI WGK: No products were found. Section 12. Ecological information Mobility : Not available. Species Period Ecotoxicity data Ingredient name LogPow BCF Persistence/degradability Bioaccumulative potential Other ecological information Other adverse effects : No known significant effects or critical hazards. Ingredient name Ingredient name BOD5 COD Ingredient name Aquatic half-life Photolysis Continued on Next Page Antibodies/Proteins in Potassium Acetate Page: 5/6 Waste Stream Not available. Section 13. Disposal considerations Denmark – Carcinogenic waste Not available. Sweden - thermoset plastic Not available. waste European waste catalogue Not available. (EWC) To present knowledge of the supplier, this product is not regarded as hazardous waste as defined by EU Directive 91/689/EC. Hazardous waste Austria - Waste catalogue Not available. Denmark - Waste card number Not available. Denmark - Waste group Not available. Sweden - Waste group Not available. Norway - Waste number Not available. Switzerland - Waste code Not available. The generation of waste should be avoided or minimized wherever possible. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Methods of disposal Norway - Hazardous waste To present knowledge of the supplier, this product is not regarded as hazardous waste as defined by SFT’s Directive on special waste. Contact the supplier for all information regarding the proper transportation method for this material. Section 14. Transport information U.S. Federal Regulations HCS Classification -- Section 15. Regulatory information TSCA 8(b) inventory: water; Potassium Acetate Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean air act (CAA) 112 accidental release prevention: No products were found. Clean air act (CAA) 112 regulated flammable substances: No products were found. Clean air act (CAA) 112 regulated toxic substances: No products were found. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/311/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. This product is not classified according to the EU regulations. Label Requirements (Europe) 1 Pennsylvania RTK: Potassium Acetate New Jersey: Potassium Acetate State regulations Continued on Next Page Antibodies/Proteins in Potassium Acetate Page: 6/6 Pennsylvania RTK: Potassium Acetate New Jersey: Potassium Acetate State Regulations CEPA DSL: water; Potassium Acetate Australia (NICNAS): water China: water Germany water class: Potassium Acetate Japan (METI): water Korea (TCCL): water Philippines (RA6969): water WHMIS (Canada) Not controlled under WHMIS (Canada). DSCL (EEC) This product is not classified according to the EU regulations. International Regulations EINECS Not available. International Lists Version 4.02 Date of previous issue 7/13/2007 Not available. Section 16. Other information References Validated by MSDS Administrator on 8/24/2007. Verified by MSDS Administrator. Printed 8/24/2007. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Hazardous Material Information System (U.S.A.) National Fire Protection Association (U.S.A.) History of Document Changes Any information changes since last document version are marked with a triangle symbol. Intended Use Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. 0 0 0 C Health Fire hazard Reactivity Personal protection 0 0 Health 0 Special Instability Flammability