Methoxyamine Hydrochloride Methoxyamine Hydrochloride MSDS Number: M2121 --- Effective Date: 05/08/00 1. Product Identification Synonyms: None CAS No.: 593-56-6 Molecular Weight: 83.52 Chemical Formula: CH3ONH2.HCl 2. Composition/Information on Ingredients Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------- --------- Methoxyamine Hydrochloride 593-56-6 97 - 100% Yes 3. Hazards Identification Emergency Overview -------------------------- DANGER! CAUSES SEVERE SKIN AND EYE BURNS. MAY CAUSE CYANOSIS BASED ON ANIMAL DATA (BLUE-GRAY SKIN AND LIPS CAUSED BY LACK OF OXYGEN) HEAT SENSITIVE. CAN VIOLENTLY DECOMPOSE IF HEATED. DUST IRRITATING TO RESPIRATORY TRACT TARGET ORGAN(S): Eyes, skin, liver, kidneys, blood, cardiovascular system, central nervous system, lungs. Potential Health Effects ---------------------------------- Inhalation: Irritation of respiratory system, headache, nausea, vomiting, dizziness, cyanosis, unconsciousness, rapid ineffective breathing, weakness, convulsions, low blood pressure, and may be fatal. Ingestion: Gastrointestinal irritation, headache, nausea, vomiting, dizziness, cyanosis, unconsciousness, rapid ineffective breathing, weakness, convulsions, low blood pressure, and may be fatal. Skin Contact: Severe burns. Eye Contact: Severe burns. Chronic Exposure: No information found. Aggravation of Pre-existing Conditions: Central nervous system disorders, kidney, liver, or blood disorders, respiratory system disease, skin disorders, thyroid disorders. 4. First Aid Measures Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Prompt action is essential. Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention. Skin Contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before re-use. Eye Contact: In case of eye contact, immediately flush with plenty of water for at least 15 minutes. 5. Fire Fighting Measures Fire: Not expected to be a fire hazard. Explosion: Fire or excessive heat may produce hazardous decomposition products. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion Fire Extinguishing Media: Water spray; Dry chemical; Carbon dioxide. Special Information: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Use water to keep fire-exposed containers cool. 6. Accidental Release Measures Sweep up material and package for safe feed to an incinerator. 7. Handling and Storage Store in a cool place. Fire or high temperatures may cause explosive decomposition especially if confined. Since the empty container retains product residue, follow label warnings even after container is empty. Keep from contact with oxidizing materials. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: None established. Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres. Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area. Other Control Measures: There is insufficient data in the published literature to assign complete numerical SAF-T-DATA* ratings and laboratory protective equipment for this product. Special precautions must be used in storage, use and handling. Protective equipment for laboratory bench use should be chosen using professional judgment based on the size and type of reaction or test to be conducted and the available ventilation, with overriding consideration to minimize contact with the chemical. 9. Physical and Chemical Properties Appearance: White crystalline solid. Odor: No information found. Solubility: Appreciable (> 10%) Specific Gravity: No information found. pH: No information found. % Volatiles by volume @ 21C (70F): 0 Boiling Point: No information found. Melting Point: 140C (284F) Vapor Density (Air=1): No information found. Vapor Pressure (mm Hg): 0 @ 20C (68F) Evaporation Rate (BuAc=1): 0 10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, Hydrogen chloride gas oxides of nitrogen. Hazardous Polymerization: Will not occur. Incompatibilities: Strong oxidizing agents. Conditions to Avoid: Avoid temperatures above 40C Can decompose above 140C 11. Toxicological Information --------\Cancer Lists\------------------------------------------------------ ---NTP Carcinogen--- Ingredient Known Anticipated IARC Category ------------------------------------ ----- ----------- ------------- Methoxyamine Hydrochloride No No None (593-56-6) 12. Ecological Information Environmental Fate: No information found. Environmental Toxicity: No information found. 13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements. 14. Transport Information Domestic (Land, D.O.T.) ----------------------- Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (METHOXYAMINE HYDROCHLORIDE) Hazard Class: 8 UN/NA: UN3261 Packing Group: II Information reported for product/size: 100G International (Water, I.M.O.) ----------------------------- Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (METHOXYAMINE HYDROCHLORIDE) Hazard Class: 8 UN/NA: UN3261 Packing Group: II Information reported for product/size: 100G 15. Regulatory Information --------\Chemical Inventory Status - Part 1\--------------------------------- Ingredient TSCA EC Japan Australia ----------------------------------------------- ---- --- ----- --------- Methoxyamine Hydrochloride (593-56-6) Yes Yes Yes Yes --------\Chemical Inventory Status - Part 2\--------------------------------- --Canada-- Ingredient Korea DSL NDSL Phil. ----------------------------------------------- ----- --- ---- ----- Methoxyamine Hydrochloride (593-56-6) Yes Yes No Yes --------\Federal, State & International Regulations - Part 1\---------------- -SARA 302- ------SARA 313------ Ingredient RQ TPQ List Chemical Catg. ----------------------------------------- --- ----- ---- -------------- Methoxyamine Hydrochloride (593-56-6) No No No No --------\Federal, State & International Regulations - Part 2\---------------- -RCRA- -TSCA- Ingredient CERCLA 261.33 8(d) ----------------------------------------- ------ ------ ------ Methoxyamine Hydrochloride (593-56-6) No No No Chemical Weapons Convention: No TSCA 12(b): No CDTA: No SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No Reactivity: No (Pure / Solid) Australian Hazchem Code: No information found. Poison Schedule: No information found. WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR. 16. Other Information Label Hazard Warning: DANGER! CAUSES SEVERE SKIN AND EYE BURNS. MAY CAUSE CYANOSIS BASED ON ANIMAL DATA (BLUE-GRAY SKIN AND LIPS CAUSED BY LACK OF OXYGEN) HEAT SENSITIVE. CAN VIOLENTLY DECOMPOSE IF HEATED. DUST IRRITATING TO RESPIRATORY TRACT TARGET ORGAN(S): Eyes, skin, liver, kidneys, blood, cardiovascular system, central nervous system, lungs. Label Precautions: No SAF-T-DATA Ratings have been developed for this product. Read and follow all warnings, precautions, instructions and other safety and handling information on the label and MSDS. Avoid contact with eyes, skin, clothing. Store in a cool place. Keep away from heat and flame. Avoid breathing dust. Use with adequate ventilation. Wash thoroughly after handling. Label First Aid: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Prompt action is essential. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Product Use: Laboratory Reagent. Revision Information: New 16 section MSDS format, all sections have been revised. Disclaimer: ************************************************************************************************ Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION. ************************************************************************************************ Prepared by: Environmental Health & Safety Phone Number: (314) 654-1600 (U.S.A.)