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Laboratory Products Safety Products Services Contact Us Customer Service GJS Mass Measurement 1-877-627-7225 Instrument Service 1-800-267-6633 Mailing Addresses Corporate Profile Employment Global Links President's Message Quality Management Policy Certificates of Analysis Material Safety Data Sheets Site Search Product Search **** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION **** MSDS Name: N,N-Dimethylformamide, 99% Catalog Numbers: AC116220200, AC116225000, AC408320040, AC423640040, AC423640200, S79999SPEC BP1160 4, BP1160 500, BP1160-4, BP1160-500, BP11604, BP1160500, BP1160RS115 BP1160RS19, BP1160RS200, BP1160RS28, BP1160RS50, BP1160SS-11, BP1160SS-20, BP1160SS-30, BP1160SS-50, BP1160SS115, BP1160SS200, BP1160SS28, BP1160SS50, BP2610100, D119 1, D119 20, D119 4, D119 500, D119-1, D119-20, D119-4, D119-500, D1191, D11920, D11920001, D11920LC, D1194, D119500, D119FB115, D119FB19, D119FB200, D119FB50, D119J4, D119RB115, D119RB19, D119RB200, D119RB50, D119RRS115, D119RS115, D119RS200, D119RS28, D119RS50, D119S 4, D119S-4, D119S4, D119SS115, D119SS200, D119SS28, D119SS50, D131 1, D131 4, D131-1, D131-4, D1311, D1314, D133-4, FLBP1160RS-115, FLBP1160RS-200, FLBP1160RS-28, FLBP1160RS-50 Synonyms: N,N-Dimethylmethanamide; DMF; DMFA. Company Identification: Fisher Scientific 1 Reagent Lane Fairlawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887 **** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS **** +----------------+--------------------------------------+----------+-----------+ | CAS# | Chemical Name | % | EINECS# | |----------------|--------------------------------------|----------|-----------| | 68-12-2 |N,N-Dimethylformamide | 99 | 200-679-5 | +----------------+--------------------------------------+----------+-----------+ Hazard Symbols: T Risk Phrases: 20/21 36 61 **** SECTION 3 - HAZARDS IDENTIFICATION **** EMERGENCY OVERVIEW Harmful by inhalation and in contact with skin. Irritating to eyes. May cause harm to the unborn child. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause liver damage. Inhalation: Causes respiratory tract irritation. Vapors may cause dizziness or suffocation. Chronic: Possible cancer hazard based on tests with laboratory animals. Prolonged or repeated skin contact may cause dermatitis. May cause reproductive and fetal effects. **** SECTION 4 - FIRST AID MEASURES **** Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Induce vomiting by giving one teaspoon of Syrup of Ipecac. Inhalation: Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Treat symptomatically and supportively. **** SECTION 5 - FIRE FIGHTING MEASURES **** General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water. **** SECTION 6 - ACCIDENTAL RELEASE MEASURES **** General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Do not flush into a sewer. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. **** SECTION 7 - HANDLING and STORAGE **** Handling: Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not ingest or inhale. Use with adequate ventilation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. **** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION **** Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR :1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. **** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES **** Physical State: Liquid Appearance: clear, colorless Odor: Faint, amine odor. pH: 6 - 8 @ 20% aq.sol. Vapor Pressure: 4.9 mbar @ 20 C Vapor Density: 2.5 (air=1) Evaporation Rate: 0.17 (butylacetate=1) Viscosity: 0.8 mPas @ 20 C Boiling Point: 153 deg C Freezing/Melting Point: 61 deg C Autoignition Temperature: 445 deg C ( 833.00 deg F) Flash Point: 57 deg C ( 134.60 deg F) Explosion Limits, lower: 2.2 Explosion Limits, upper: 15.2 Decomposition Temperature: Not available. Solubility: Completely soluble in water. Specific Gravity/Density: 0.9450 Molecular Formula: C3H7NO Molecular Weight: 73.0551 **** SECTION 10 - STABILITY AND REACTIVITY **** Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Mechanical shock, incompatible materials, ignition sources, excess heat, temperatures above 55&C. Incompatibilities with Other Materials: Oxidizing materials, ammonia, anhydrides, iron, nitrates, phenols, isocyanates, acids (mineral, non-oxidizing, e.g. hydrochloric acid, hydrofluoric acid, muriatic acid, phosphoric acid), acids (mineral, oxidizing, e.g. chromic acid, hypochlorous acid, nitric acid, sulfuric acid), metals (alkali and alkaline, e.g. cesium, potassium, sodium), metals and metal compounds (toxic, e.g. beryllium, lead acetate, nickel carbonyl, tetraethyl lead), oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), reducing agents (strong, e.g. aluminum carbide, chlorosilane, hydrogen phosphide, lithium hydride), water reactive substances (e.g. acetic anyhdride, alkyl aluminum chloride, calcium carbide, ethyl dichlorosilane), carbontetrachloride, chlorinated hydrocarbons, violent reaction with halogens, organic materials. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Will not occur. **** SECTION 11 - TOXICOLOGICAL INFORMATION **** RTECS#: CAS# 68-12-2: LQ2100000 LD50/LC50: CAS# 68-12-2: Inhalation, mouse: LC50 = 9400 mg/m3/2H; Oral, mouse: LD50 = 2900 mg/kg; Oral, rabbit: LD50 = 5 gm/kg; Oral, rat: LD50 = 2800 mg/kg; Skin, rabbit: LD50 = 4720 mg/kg. Carcinogenicity: N,N-Dimethylformamide - ACGIH: A4 - Not Classifiable as a Human Carcinogen IARC: Group 3 carcinogen Epidemiology: No information available. Teratogenicity: No information available. Reproductive Effects: No information available. Neurotoxicity: No information available. Mutagenicity: No information available. Other Studies: No data available. **** SECTION 12 - ECOLOGICAL INFORMATION **** **** SECTION 13 - DISPOSAL CONSIDERATIONS **** Dispose of in a manner consistent with federal, state, and local regulations. **** SECTION 14 - TRANSPORT INFORMATION **** US DOT Shipping Name: N,N-DIMETHYLFORMAMIDE Hazard Class: 3 UN Number: UN2265 Packing Group: III Canadian TDG Shipping Name: N N DIMETHYLFORMAMIDE Hazard Class: 3 UN Number: UN2265 Other Information: FLASHPOINT 58C **** SECTION 15 - REGULATORY INFORMATION **** US FEDERAL TSCA CAS# 68-12-2 is listed on the TSCA inventory. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE N,N-Dimethylformamide can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 20/21 Harmful by inhalation and in contact with skin. R 36 Irritating to eyes. R 61 May cause harm to the unborn child. Safety Phrases: S 53 Avoid exposure - obtain special instructions before use. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 68-12-2: 1 United Kingdom Occupational Exposure Limits CAS# 68-12-2: OES-United Kingdom, TWA 10 ppm TWA; 30 mg/m3 TWA CAS# 68-12-2: OES-United Kingdom, STEL 20 ppm STEL; 61 mg/m3 STEL Canada CAS# 68-12-2 is listed on Canada's DSL List. CAS# 68-12-2 is listed on Canada's Ingredient Disclosure List. Exposure Limits CAS# 68-12-2: OEL-AUSTRALIA:TWA 10 ppm (30 mg/m3);Skin OEL-BELGIUM:TWA 10 ppm (30 mg/m3);Skin OEL-CZECHOSLOVAKIA:TWA 30 mg/m3;STEL 60 mg/m3 OEL-DENMARK:TWA 10 ppm (30 mg/m3);Skin OEL-FINLAND:TWA 10 ppm (30 mg/m3);STEL 20 ppm (60 mg/m3);Skin OEL-FRANCE:TWA 10 ppm (30 mg/m3);Skin OEL-GERMANY:TWA 20 ppm (60 mg/m3);Skin OEL-HUNGARY:TWA 10 mg/m3;STEL 20 mg/m3;Skin OEL-JAPAN:TWA 10 ppm (30 mg/m3);Skin OEL-THE NETHERLANDS:TWA 10 ppm (30 mg/m3);Skin OEL-THE PHILIPPINES:TWA 10 ppm (30 mg/m3);Skin OEL-POLAND:TWA 10 mg/m3 OEL-RUSSIA:TWA 10 ppm;STEL 10 mg/m3;Skin OEL-SWEDEN:TWA 10 ppm (30 mg/m3);STEL 15 ppm (45 mg/m3);Skin OEL-SWITZERLAND:TWA 10 ppm (30 mg/m3);STEL 20 ppm;Skin OEL-TURKEY:TWA 10 ppm (30 mg/m3);Skin OEL-UNITED KINGDOM:TWA 10 ppm (30 mg/m3);STEL 20 ppm;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV **** SECTION 16 - ADDITIONAL INFORMATION **** MSDS Creation Date: 5/25/1999 Revision #2 Date: 8/02/2000 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------