Kit Components 01/17/2008
Product code Description
1610449 Silver Stain Plus™ Kit
1610449EDU
Components:
1610448 Development Accelerator Reagent
1610461 Fixative Enhancer Concentrate
1610462 Silver Complex Solution
1610463 Reduction Moderator Solution
1610464 Image Development Reagent
Page 1/5
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
DR
1 Identification of substance:
· Product details:
· Trade name: Development Accelerator Reagent
· Catalog or product number: 1610448, 1610448EDU
· Application of the substance / the preparation Laboratory chemicals
· Manufacturer/Supplier:
Bio-Rad Laboratories, Life Science Group
2000 Alfred Nobel Drive
Hercules, California 94547 (510)741-1000
· Information department: Technical services, customer support.
· Emergency information:
1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT.
510-741-1000
* 2 Composition/Information on components:
· Chemical characterization:
· CAS No. Description:
497-19-8 sodium carbonate
· Identification number(s):
· EINECS Number: 207-838-8
· EU Number: 011-005-00-2
· Additional information: For the wording of the listed risk phrases refer to section 16.
* 3 Hazards identification
· Emergency overview:
Irritant to eyes.
Xi Irritant
· Information pertaining to particular dangers for man and environment
R 36 Irritating to eyes.
· Classification system
The classification was made according to OSHA 29CFR 1910.1200 and 1910.1030, and is expanded upon from company and/or
literature information.
4 First aid measures
· After inhalation Supply fresh air; consult doctor in case of complaints.
· After skin contact Generally the product does not irritate the skin.
· After eye contact Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
· After swallowing Induce vomiting and call for medical help.
5 Fire fighting measures
· Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· Protective equipment: No special measures required.
USA
(Contd. on page 2)
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Development Accelerator Reagent
(Contd. of page 1)
DR
6 Accidental release measures
· Person-related safety precautions: Not required
· Measures for environmental protection: Do not allow to enter sewers/ surface or ground water.
· Measures for cleaning/collecting: Pick up mechanically.
7 Handling and storage
· Handling
· Information for safe handling:
No special measures required.
Prevent formation of dust.
No special precautions are necessary if used correctly.
· Information about protection against explosions and fires: No special measures required.
· Storage
· Requirements to be met by storerooms and receptacles: According to product specification
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: Keep receptacle tightly sealed.
8 Exposure controls and personal protection
· Additional information about design of technical systems: No further data; see item 7.
· Components with limit values that require monitoring at the workplace: Not required.
· Additional information: The lists that were valid during the creation were used as basis.
· Personal protective equipment
· General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
· Breathing equipment:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective
device that is independent of circulating air.
· Protection of hands: Protective gloves.
· Material of gloves Synthetic gloves
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
· Eye protection:
Safety glasses
Tightly sealed goggles.
9 Physical and chemical properties:
· General Information
Form: Crystalline powder
Color: White
Odor: Odorless
(Contd. on page 3)
USA
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Development Accelerator Reagent
(Contd. of page 2)
DR
· Change in condition
Melting point/Melting range: 854°C
Boiling point/Boiling range: undetermined
· Flash point: Not applicable
· Flammability (solid, gaseous) Product is not flammable.
· Danger of explosion: Product does not present an explosion hazard.
· Density at 20°C: 2.533 g/cm³
· Bulk density at 20°C: 500-600 kg/m³
· Solubility in / Miscibility with
Water at 20°C: 212 g/l
· pH-value at 20°C: 11.5
· Organic solvents: 0.0 %
· Solids content: 100.0 %
10 Stability and reactivity
· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Dangerous reactions No dangerous reactions known
· Dangerous products of decomposition: No dangerous decomposition products known
11 Toxicological information
· Acute toxicity:
· LD/LC50 values for hazardous components per OSHA criteria:
497-19-8 sodium carbonate
Oral LD50 4000 mg/kg (rat)
· Primary irritant effect:
· on the skin: No irritant effect.
· on the eye: Irritant effect.
· Sensitization: No sensitizing effects known.
· Target organs: Eye.
12 Ecological information:
· General notes:
Water hazard class 1 (German Regulation) (Assessment by list): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
Rinse off of bigger amounts into drains or the aquatic environment may lead to increased pH-values. A high pH-value harms aquatic
organisms. In the dilution of the use-level the pH-value is considerably reduced, so that after the use of the product the aqueous waste,
emptied into drains, is only low water-dangerous.
USA
(Contd. on page 4)
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Development Accelerator Reagent
(Contd. of page 3)
DR
13 Disposal considerations
· Product:
· Recommendation
Hand over to hazardous waste disposers.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
14 Transport information
· DOT regulations:
· Hazard class: -
· Land transport ADR/RID (cross-border)
· ADR/RID class: -
· Maritime transport IMDG:
· IMDG Class: -
· Marine pollutant: No
· Air transport ICAO-TI and IATA-DGR:
· ICAO/IATA Class: -
* 15 Regulations
· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)
· Section 302/304 (40CFR355.30 / 40CFR355.40):
Substance not listed.
· Section 313 (40CFR372.65):
Substance is not listed.
· TSCA (Toxic Substances Control Act):
Substance is listed.
· Cancerogenity categories
· EPA (Environmental Protection Agency)
Substance is not listed.
· IARC (International Agency for Research on Cancer)
Substance is not listed.
· NTP (National Toxicology Program)
Substance is not listed.
· TLV (Threshold Limit Value established by ACGIH)
Substance is not listed.
· MAK (German Maximum Workplace Concentration)
Substance is not listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)
Substance is not listed.
(Contd. on page 5)
USA
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Material Safety Data Sheet
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Trade name: Development Accelerator Reagent
(Contd. of page 4)
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· OSHA-Ca (Occupational Safety & Health Administration)
Substance is not listed.
· Markings according to EU guidelines:
The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials
· Code letter and hazard designation of product:
Xi Irritant
· Risk phrases:
36 Irritating to eyes.
· Safety phrases:
22 Do not breathe dust.
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
· National regulations
· Water hazard class: Water hazard class 1 (Assessment by list): slightly hazardous for water.
16 Other information:
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and
shall not establish a legally valid contractual relationship.
· Department issuing MSDS: Environmental Health and Safety.
· Contact:
Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000
Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000
· * Data compared to the previous version altered.
USA
Page 1/5
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
DR
* 1 Identification of substance:
· Product details:
· Trade name: Fixative Enhancer Concentrate
· Catalog or product number: 1610461, 1610461EDU
· Application of the substance / the preparation Laboratory chemicals
· Manufacturer/Supplier:
Bio-Rad Laboratories, Life Science Group
2000 Alfred Nobel Drive
Hercules, California 94547 (510)741-1000
· Information department: Technical services, customer support.
· Emergency information:
1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT.
510-741-1000
* 2 Composition/Information on components:
· Chemical characterization
· Description: Mixture of the substances listed below with non-hazardous additions.
· Listing of dangerous and non-hazardous components:
CAS: 56-81-5
EINECS: 200-289-5
RTECS: MA 8050000
glycerol 35-50%
CAS: 7732-18-5
EINECS: 231-791-2
RTECS: ZC 0110000
water 35-50%
· Additional information For the wording of the listed risk phrases refer to section 15.
* 3 Hazards identification
· Emergency overview: not applicable
· Information pertaining to particular dangers for man and environment
The product does not have to be labelled due to the calculation procedure of the "General Classification guideline for preparations of
the EU" in the latest valid version.
· Classification system
The classification was made according to the latest editions of the EU-lists, and expanded upon from company and literature data.
4 First aid measures
· General information No special measures required.
· After inhalation Supply fresh air; consult doctor in case of complaints.
· After skin contact Generally the product does not irritate the skin.
· After eye contact Rinse opened eye for several minutes under running water.
· After swallowing Induce vomiting and call for medical help.
5 Fire fighting measures
· Suitable extinguishing agents Use fire fighting measures that suit the environment.
(Contd. on page 2)
USA
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Material Safety Data Sheet
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Trade name: Fixative Enhancer Concentrate
(Contd. of page 1)
DR
· Protective equipment: No special measures required.
6 Accidental release measures
· Person-related safety precautions: Not required
· Measures for environmental protection: Dilute with plenty of water.
· Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
· Additional information: No dangerous substances are released.
* 7 Handling and storage
· Handling
· Information for safe handling:
No special measures required.
No special precautions are necessary if used correctly.
· Information about protection against explosions and fires: No special measures required.
· Storage
· Requirements to be met by storerooms and receptacles: According to product specification
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: None.
* 8 Exposure controls and personal protection
· Additional information about design of technical systems: No further data; see item 7.
· Components with limit values that require monitoring at the workplace:
56-81-5 glycerol
PEL ()
TLV ()
15* 5** mg/m³
*total dust **respirable fraction
10 ppm
· Additional information: The lists that were valid during the creation were used as basis.
· Personal protective equipment
· General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed.
· Breathing equipment: Not required.
· Protection of hands: Protective gloves.
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from
manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be
calculated in advance and has therefore to be checked prior to the application.
Synthetic gloves
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
· Eye protection: Safety glasses
USA
(Contd. on page 3)
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Fixative Enhancer Concentrate
(Contd. of page 2)
DR
* 9 Physical and chemical properties:
· General Information
Form: liquid
Color: Colorless
Odor: Odorless
· Change in condition
Melting point/Melting range: undetermined
Boiling point/Boiling range: 100°C
· Flash point: > 100°C
· Ignition temperature: 400°C
· Auto igniting: Product is not selfigniting.
· Danger of explosion: Product does not present an explosion hazard.
· Explosion limits:
Lower: 0.9 Vol %
· Vapor pressure at 20°C: 23 hPa
· Density at 20°C: 1.11504 g/cm³
· Solubility in / Miscibility with
Water: Fully miscible
· Solvent content:
· Organic solvents: 50.0 %
· Water: 50.0 %
10 Stability and reactivity
· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Dangerous reactions No dangerous reactions known
· Dangerous products of decomposition: No dangerous decomposition products known
* 11 Toxicological information
· Acute toxicity:
· Primary irritant effect:
· on the skin: No irritant effect.
· on the eye: No irritant effect.
· Sensitization: No sensitizing effects known.
· Additional toxicological information:
The product is not subject to classification according to the calculation method of the General EU Classification Guidelines for
Preparations as issued in the latest version:
When used and handled according to specifications, the product does not have any harmful effects according to our experience and the
information provided to us.
· Target organs: Not applicable.
USA
(Contd. on page 4)
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Material Safety Data Sheet
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Trade name: Fixative Enhancer Concentrate
(Contd. of page 3)
DR
* 12 Ecological information:
· General notes: Generally not hazardous for water.
13 Disposal considerations
· Product:
· Recommendation Hand over to hazardous waste disposers.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
· DOT regulations:
· Hazard class: -
· Land transport ADR/RID (cross-border)
· ADR/RID class: -
· Maritime transport IMDG:
· IMDG Class: -
· Marine pollutant: No
· Air transport ICAO-TI and IATA-DGR:
· ICAO/IATA Class: -
· Transport/Additional information: Not dangerous according to the above specifications.
* 15 Regulations
· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)
· Section 302/304 (40CFR355.30 / 40CFR355.40):
None of the ingredients is listed.
· Section 313 (40CFR372.65):
None of the ingredients is listed.
· TSCA (Toxic Substances Control Act):
All ingredients are listed.
· Cancerogenity categories
· EPA (Environmental Protection Agency)
None of the ingredients is listed.
· IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
· NTP (National Toxicology Program)
None of the ingredients is listed.
· TLV (Threshold Limit Value established by ACGIH)
None of the ingredients is listed.
(Contd. on page 5)
USA
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Material Safety Data Sheet
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Trade name: Fixative Enhancer Concentrate
(Contd. of page 4)
DR
· MAK (German Maximum Workplace Concentration)
None of the ingredients is listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients is listed.
· OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.
· Markings according to EU guidelines:
Observe the general safety regulations when handling chemicals
The product is not subject to identification regulations under EU Directives and the Ordinance on Hazardous Materials (GefStoffV).
· Safety phrases:
60 This material and its container must be disposed of as hazardous waste.
· National regulations
Class Share in %
NK 35-50
· Water hazard class: Generally not hazardous for water.
16 Other information:
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and
shall not establish a legally valid contractual relationship.
· Department issuing MSDS: Environmental Health and Safety.
· Contact:
Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000
Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000
· * Data compared to the previous version altered.
USA
Page 1/5
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 05/03/2007
DR
* 1 Identification of substance:
· Product details:
· Trade name: Silver Complex Solution
· Catalog or product number: 1610462, 1610462EDU
· Application of the substance / the preparation Laboratory chemicals
· Manufacturer/Supplier:
Bio-Rad Laboratories, Life Science Group
2000 Alfred Nobel Drive
Hercules, California 94547 (510)741-1000
· Information department: Technical services, customer support.
· Emergency information:
1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT.
510-741-1000
1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT.
* 2 Composition/Information on components:
· Chemical characterization:
· CAS No. Description:
7732-18-5 water
· Identification number(s):
· EINECS Number: 231-791-2
· Additional information: For the wording of the listed risk phrases refer to section 16.
· Chemical characterization
· Listing of dangerous and non-hazardous components:
CAS: 7761-88-8
EINECS: 231-853-9
silver nitrate C, N; R 34-50/53 1.0-2.5%
CAS: 6484-52-2
EINECS: 229-347-8
RTECS: BR9050000
ammonium nitrate O; R 8-9 1.0-2.5%
* 3 Hazards identification
· Emergency overview: not applicable
· Information pertaining to particular dangers for man and environment
R 52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
· Classification system
The classification was made according to OSHA 29CFR 1910.1200 and 1910.1030, and is expanded upon from company and/or
literature information.
* 4 First aid measures
· After inhalation Supply fresh air; consult doctor in case of complaints.
· After skin contact Generally the product does not irritate the skin.
· After eye contact Rinse opened eye for several minutes under running water.
· After swallowing Induce vomiting and call for medical help.
USA
(Contd. on page 2)
Page 2/5
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 05/03/2007
Trade name: Silver Complex Solution
(Contd. of page 1)
DR
5 Fire fighting measures
· Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· Protective equipment: No special measures required.
* 6 Accidental release measures
· Person-related safety precautions: Not required
· Measures for environmental protection:
Inform respective authorities in case of seepage into water course or sewage system.
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
· Measures for cleaning/collecting: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
* 7 Handling and storage
· Handling
· Information for safe handling:
No special measures required.
No special precautions are necessary if used correctly.
· Information about protection against explosions and fires: No special measures required.
· Storage
· Requirements to be met by storerooms and receptacles: According to product specification
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: None.
* 8 Exposure controls and personal protection
· Additional information about design of technical systems: No further data; see item 7.
· Components with limit values that require monitoring at the workplace: Not required.
· Additional information: The lists that were valid during the creation were used as basis.
· Personal protective equipment
· General protective and hygienic measures Wash hands before breaks and at the end of work.
· Breathing equipment: Not required.
· Protection of hands: Protective gloves.
· Material of gloves Synthetic gloves
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
· Eye protection: Safety glasses
9 Physical and chemical properties:
· General Information
Form: liquid
Color: Colorless
Odor: Odorless
(Contd. on page 3)
USA
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Material Safety Data Sheet
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Trade name: Silver Complex Solution
(Contd. of page 2)
DR
· Change in condition
Melting point/Melting range: 0°C
Boiling point/Boiling range: 100°C
· Flash point: Not applicable
· Danger of explosion: Product does not present an explosion hazard.
· Vapor pressure at 20°C: 23 hPa
· Density at 20°C: 1 g/cm³
· Solubility in / Miscibility with
Water: Fully miscible
· Organic solvents: 0.0 %
· Water: 96.0 %
· Solids content: 4.0 %
10 Stability and reactivity
· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Dangerous reactions No dangerous reactions known
· Dangerous products of decomposition: No dangerous decomposition products known
* 11 Toxicological information
· Acute toxicity:
· Primary irritant effect:
· on the skin: No irritant effect.
· on the eye: No irritant effect.
· Sensitization: No sensitizing effects known.
* 12 Ecological information:
· Ecotoxical effects:
· Remark: Harmful to fish
· General notes:
Water hazard class 2 (Self-assessment): hazardous for water.
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
Harmful to aquatic organisms
* 13 Disposal considerations
· Product:
· Recommendation
Hand over to hazardous waste disposers.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
(Contd. on page 4)
USA
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Material Safety Data Sheet
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Trade name: Silver Complex Solution
(Contd. of page 3)
DR
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.
* 14 Transport information
· DOT regulations:
· Hazard class: -
· Land transport ADR/RID (cross-border)
· ADR/RID class: -
· Maritime transport IMDG:
· IMDG Class: -
· Marine pollutant: No
· Air transport ICAO-TI and IATA-DGR:
· ICAO/IATA Class: -
* 15 Regulations
· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)
· Section 302/304 (40CFR355.30 / 40CFR355.40):
Substance not listed.
· Section 313 (40CFR372.65):
6484-52-2 ammonium nitrate
· TSCA (Toxic Substances Control Act):
Substance is listed.
· Cancerogenity categories
· EPA (Environmental Protection Agency)
Substance is not listed.
· IARC (International Agency for Research on Cancer)
Substance is not listed.
· NTP (National Toxicology Program)
Substance is not listed.
· TLV (Threshold Limit Value established by ACGIH)
Substance is not listed.
· MAK (German Maximum Workplace Concentration)
Substance is not listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)
Substance is not listed.
· OSHA-Ca (Occupational Safety & Health Administration)
Substance is not listed.
· Markings according to EU guidelines:
Observe the general safety regulations when handling chemicals
(Contd. on page 5)
USA
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 05/03/2007
Trade name: Silver Complex Solution
(Contd. of page 4)
DR
The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials
· Risk phrases:
52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
· Safety phrases:
60 This material and its container must be disposed of as hazardous waste.
61 Avoid release to the environment. Refer to special instructions/Safety data sheets
· National regulations
· Water hazard class: Water hazard class 2 (Self-assessment): hazardous for water.
16 Other information:
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and
shall not establish a legally valid contractual relationship.
· Department issuing MSDS: Environmental Health and Safety.
· Contact:
Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000
Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000
· * Data compared to the previous version altered.
USA
Page 1/6
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
DR
1 Identification of substance:
· Product details:
· Trade name: Reduction Moderator Solution
· Catalog or product number: 1610463, 1610463EDU
· Application of the substance / the preparation Laboratory chemicals
· Manufacturer/Supplier:
Bio-Rad Laboratories, Life Science Group
2000 Alfred Nobel Drive
Hercules, California 94547 (510)741-1000
· Information department: Technical services, customer support.
· Emergency information:
1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT.
510-741-1000
2 Composition/Information on components:
· Chemical characterization
· Description: Mixture of the substances listed below with non-hazardous additions.
· Listing of dangerous and non-hazardous components:
CAS: 7732-18-5
EINECS: 231-791-2
RTECS: ZC 0110000
water 50-100%
CAS: 12027-43-9 Tungstosilicic acid hydrate Xi; R 36/37/38 5-10%
· Additional information For the wording of the listed risk phrases refer to section 15.
* 3 Hazards identification
· Emergency overview:
Corrosive.
May cause irreversible eye damage.
C Corrosive
· Information pertaining to particular dangers for man and environment
The product has to be labelled due to the calculation procedure of the "General Classification guideline for preparations of the EU" in
the latest valid version.
R 34 Causes burns.
· Classification system
The classification was made according to the latest editions of the EU-lists, and expanded upon from company and literature data.
4 First aid measures
· General information Immediately remove any clothing soiled by the product.
· After inhalation In case of unconsciousness place patient stably in side position for transportation.
· After skin contact Immediately wash with water and soap and rinse thoroughly.
· After eye contact Rinse opened eye for several minutes under running water. Then consult a doctor.
· After swallowing Drink copious amounts of water and provide fresh air. Immediately call a doctor.
USA
(Contd. on page 2)
Page 2/6
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Reduction Moderator Solution
(Contd. of page 1)
DR
5 Fire fighting measures
· Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· Protective equipment: No special measures required.
6 Accidental release measures
· Person-related safety precautions: Wear protective equipment (See section 8). Keep unprotected persons away.
· Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
· Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Use neutralizing agent.
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
7 Handling and storage
· Handling
· Information for safe handling:
No special measures required.
Ensure good ventilation/exhaustion at the workplace.
Prevent formation of aerosols.
No special precautions are necessary if used correctly.
· Information about protection against explosions and fires: No special measures required.
· Storage
· Requirements to be met by storerooms and receptacles: According to product specification
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: Keep receptacle tightly sealed.
* 8 Exposure controls and personal protection
· Additional information about design of technical systems: No further data; see item 7.
· Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace.
· Additional information: The lists that were valid during the creation were used as basis.
· Personal protective equipment
· General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.
· Breathing equipment:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective
device that is independent of circulating air.
· Protection of hands: Protective gloves.
(Contd. on page 3)
USA
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Reduction Moderator Solution
(Contd. of page 2)
DR
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from
manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be
calculated in advance and has therefore to be checked prior to the application.
Synthetic gloves
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
· Eye protection:
Safety glasses
Tightly sealed goggles.
* 9 Physical and chemical properties:
· General Information
Form: liquid
Color: Colorless
Odor: Odorless
· Change in condition
Melting point/Melting range: undetermined
Boiling point/Boiling range: 100°C
· Flash point: Not applicable
· Auto igniting: Product is not selfigniting.
· Danger of explosion: Product does not present an explosion hazard.
· Vapor pressure at 20°C: 23 hPa
· Density: Not determined
· Solubility in / Miscibility with
Water: Fully miscible
· pH-value at 20°C: 1.5
· Solvent content:
· Organic solvents: 0.0 %
· Water: 90.0 %
· Solids content: 10.0 %
10 Stability and reactivity
· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Dangerous reactions No dangerous reactions known
· Dangerous products of decomposition: No dangerous decomposition products known
11 Toxicological information
· Acute toxicity:
· Primary irritant effect:
· on the skin: Caustic effect on skin and mucous membranes.
(Contd. on page 4)
USA
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Material Safety Data Sheet
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Trade name: Reduction Moderator Solution
(Contd. of page 3)
DR
· on the eye: Strong caustic effect.
· Sensitization: No sensitizing effects known.
· Additional toxicological information:
The product shows the following dangers according to the calculation method of the General EU Classification Guidelines for
Preparations as issued in the latest version:
Corrosive
Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of esophagus and stomach.
· Target organs: Skin.
12 Ecological information:
· General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
Must not reach bodies of water or drainage ditch undiluted or unneutralized.
Rinse off of bigger amounts into drains or the aquatic environment may lead to decreased pH-values. A low pH-value harms aquatic
organisms. In the dilution of the use-level the pH-value is considerably increased, so that after the use of the product the aqueous waste,
emptied into drains, is only low water-dangerous.
13 Disposal considerations
· Product:
· Recommendation
Hand over to hazardous waste disposers.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.
14 Transport information
· DOT regulations:
· Hazard class: -
· Land transport ADR/RID (cross-border)
· ADR/RID class: -
· Maritime transport IMDG:
· IMDG Class: -
· Marine pollutant: No
· Air transport ICAO-TI and IATA-DGR:
· ICAO/IATA Class: -
USA
(Contd. on page 5)
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Material Safety Data Sheet
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Trade name: Reduction Moderator Solution
(Contd. of page 4)
DR
* 15 Regulations
· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)
· Section 302/304 (40CFR355.30 / 40CFR355.40):
None of the ingredients is listed.
· Section 313 (40CFR372.65):
None of the ingredients is listed.
· TSCA (Toxic Substances Control Act):
7732-18-5 water
· Cancerogenity categories
· EPA (Environmental Protection Agency)
None of the ingredients is listed.
· IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
· NTP (National Toxicology Program)
None of the ingredients is listed.
· TLV (Threshold Limit Value established by ACGIH)
None of the ingredients is listed.
· MAK (German Maximum Workplace Concentration)
None of the ingredients is listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients is listed.
· OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.
· Markings according to EU guidelines:
The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials
· Code letter and hazard designation of product:
C Corrosive
· Risk phrases:
34 Causes burns.
· Safety phrases:
23 Do not breathe gas/fumes/vapour/spray.
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
45 In case of accident or if you feel unwell, seek medical advice immediately.
60 This material and its container must be disposed of as hazardous waste.
· National regulations
· Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
16 Other information:
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and
shall not establish a legally valid contractual relationship.
· Department issuing MSDS: Environmental Health and Safety.
(Contd. on page 6)
USA
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 01/16/2008
Trade name: Reduction Moderator Solution
(Contd. of page 5)
DR
· Contact:
Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000
Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000
· * Data compared to the previous version altered.
USA
Page 1/5
Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 06/21/2007
DR
1 Identification of substance:
· Product details:
· Trade name: Image Development Reagent
· Catalog or product number: 1610464, 1610464EDU
· Application of the substance / the preparation Laboratory chemicals
· Manufacturer/Supplier:
Bio-Rad Laboratories, Life Science Group
2000 Alfred Nobel Drive
Hercules, California 94547 (510)741-1000
· Information department: Technical services, customer support.
· Emergency information:
1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION or ACCIDENT.
510-741-1000
* 2 Composition/Information on components:
· Chemical characterization:
· CAS No. Description:
7732-18-5 water
· Identification number(s):
· EINECS Number: 231-791-2
· Additional information: For the wording of the listed risk phrases refer to section 16.
· Chemical characterization
· Listing of dangerous and non-hazardous components:
CAS: 50-00-0
EINECS: 200-001-8
RTECS: LP 8925000
formaldehyde Carc. Cat. 3; T, C; R 23/24/25-34-40-43 2.5-5%
3 Hazards identification
· Emergency overview:
Irritant to skin.
Sensitizer by dermal contact.
Irritant to respiratory system and skin.
Xn Harmful
· Routes of exposure: Skin
· Information pertaining to particular dangers for man and environment
R 40 Limited evidence of a carcinogenic effect.
R 43 May cause sensitization by skin contact.
· Classification system
The classification was made according to OSHA 29CFR 1910.1200 and 1910.1030, and is expanded upon from company and/or
literature information.
4 First aid measures
· After inhalation
Supply fresh air and to be sure call for a doctor.
In case of unconsciousness place patient stably in side position for transportation.
· After skin contact Immediately wash with water and soap and rinse thoroughly.
(Contd. on page 2)
USA
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Material Safety Data Sheet
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Trade name: Image Development Reagent
(Contd. of page 1)
DR
· After eye contact Rinse opened eye for several minutes under running water. Then consult a doctor.
· After swallowing Induce vomiting and call for medical help.
5 Fire fighting measures
· Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· Protective equipment: No special measures required.
6 Accidental release measures
· Person-related safety precautions: Not required
· Measures for environmental protection:
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
· Measures for cleaning/collecting:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Dispose contaminated material as waste according to item 13.
7 Handling and storage
· Handling
· Information for safe handling: No special precautions are necessary if used correctly.
· Information about protection against explosions and fires: No special measures required.
· Storage
· Requirements to be met by storerooms and receptacles: According to product specification
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: None.
8 Exposure controls and personal protection
· Additional information about design of technical systems: No further data; see item 7.
· Components with limit values that require monitoring at the workplace:
50-00-0 formaldehyde
PEL ()
REL ()
TLV ()
Short-term value: 2 ppm
Long-term value: 0.75 ppm
see 29 CFR 1910.1048
Short-term value: C 0.1* ppm
Long-term value: 0.016 ppm
*15-min
Short-term value: C 0.37 mg/m³, C 0.3 ppm
SEN
· Additional information: The lists that were valid during the creation were used as basis.
· Personal protective equipment
· General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing
Wash hands before breaks and at the end of work.
(Contd. on page 3)
USA
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Material Safety Data Sheet
Printing date 01/17/2008 Reviewed on 06/21/2007
Trade name: Image Development Reagent
(Contd. of page 2)
DR
· Breathing equipment: Not required.
· Protection of hands: Protective gloves.
· Material of gloves Synthetic gloves
· Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
· Eye protection: Safety glasses
9 Physical and chemical properties:
· General Information
Form: liquid
Color: Colorless
Odor: Odorless
· Change in condition
Melting point/Melting range: 0°C
Boiling point/Boiling range: 100°C
· Flash point: Not applicable
· Danger of explosion: Product does not present an explosion hazard.
· Vapor pressure at 20°C: 23 hPa
· Density at 20°C: 1 g/cm³
· Solubility in / Miscibility with
Water: Fully miscible
· Organic solvents: 2.8 %
· Water: 97.2 %
10 Stability and reactivity
· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
· Dangerous reactions No dangerous reactions known
· Dangerous products of decomposition: No dangerous decomposition products known
11 Toxicological information
· Acute toxicity:
· LD/LC50 values for hazardous components per OSHA criteria:
50-00-0 formaldehyde
Oral LD50 >200 mg/kg (rat)
· Primary irritant effect:
· on the skin: No irritant effect.
· on the eye: No irritant effect.
· Sensitization: Sensitization possible through skin contact.
· Target organs: Skin.
USA
(Contd. on page 4)
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Material Safety Data Sheet
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(Contd. of page 3)
DR
12 Ecological information:
· General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
13 Disposal considerations
· Product:
· Recommendation
Hand over to hazardous waste disposers.
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.
14 Transport information
· DOT regulations:
· Hazard class: -
· Land transport ADR/RID (cross-border)
· ADR/RID class: -
· Maritime transport IMDG:
· IMDG Class: -
· Marine pollutant: No
· Air transport ICAO-TI and IATA-DGR:
· ICAO/IATA Class: -
* 15 Regulations
· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)
· Section 302/304 (40CFR355.30 / 40CFR355.40):
50-00-0 formaldehyde
· Section 313 (40CFR372.65):
50-00-0 formaldehyde
· TSCA (Toxic Substances Control Act):
Substance is listed.
· California Proposition 65:
· Chemicals known to cause cancer:
50-00-0 formaldehyde
· Cancerogenity categories
· EPA (Environmental Protection Agency)
Substance is not listed.
(Contd. on page 5)
USA
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Material Safety Data Sheet
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Trade name: Image Development Reagent
(Contd. of page 4)
DR
· IARC (International Agency for Research on Cancer)
50-00-0 formaldehyde 1
· NTP (National Toxicology Program)
50-00-0 formaldehyde R
· TLV (Threshold Limit Value established by ACGIH)
Substance is not listed.
· MAK (German Maximum Workplace Concentration)
Substance is not listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)
Substance is not listed.
· OSHA-Ca (Occupational Safety & Health Administration)
Substance is not listed.
· Markings according to EU guidelines:
The product has been classified and marked in accordance with EU Directives / Ordinance on Hazardous Materials
· Code letter and hazard designation of product:
Xn Harmful
· Risk phrases:
40 Limited evidence of a carcinogenic effect.
43 May cause sensitization by skin contact.
· Safety phrases:
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
45 In case of accident or if you feel unwell, seek medical advice immediately.
51 Use only in well-ventilated areas.
60 This material and its container must be disposed of as hazardous waste.
· National regulations
Class Share in %
I 2.5-5
· Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.
16 Other information:
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and
shall not establish a legally valid contractual relationship.
· Department issuing MSDS: Environmental Health and Safety.
· Contact:
Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000
Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000
· * Data compared to the previous version altered.
USA