ÿþPage 1 of 5 MATERIAL SAFETY DATA SHEET Section 1 Company and Product Identification Product Name FREE T3 CALIBRATORS S0, S1, S2, S3, S4, S5 Part Number 33855 Doc. ID 3385575 AA Issued (day/month/year) 21/10/1998 Series Name ACCESSâ Manufacturer Beckman Instruments, Inc. 2500 Harbor Blvd. Fullerton, CA 928343100, U.S.A. Distributor and Emergency Phone No. % Refer to attached list, Document ID: 472050, for local distributor and emergency phone numbers. Section 2 Composition and Information on Ingredients Hazardous Ingredients: Meets Hazardous Criteria: Chemical Name CAS # % by wt. EU US OSHA WHMIS ProClin* 300  <0.7 Yes No Exempt See Section 15 Regulatory Information for additional information on ingredient hazard classifications. Section 3 Hazards Identification Emergency Overview Light yellow; Translucent; Liquid; Musty Nonflammable aqueous solution. Skin, eye and respiratory tract irritant. Contains material of human origin. Physical Hazards No physical hazards were determined from a review of available literature. Potential Health Effects Summary Exposure may result in irritation of skin, eyes, and mucous membranes. See Section 11 Toxicological Information for more detailed health information. Product Hazard Classifications EU: Xi;R43 WHMIS: Exempt US OSHA: Not applicable Section 4 First Aid Measures Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not breathing, begin artificial respiration immediately and obtain medical attention. Eye Contact If product is splashed in eyes, wash eyes under gently running water for 15 minutes or longer, making sure that the eyelids are held open. Obtain medical attention. ã1998 Beckman Instruments, Inc. Global MSDS  English FREE T3 CALIBRATORS S0, S1, S2, S3, S4, S5 MSDS # 3385575 AA Page 2 of 5 Section 4 First Aid Measures (Continued) Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes. Then gently wash skin with soap and water; rinse well. If product contacted broken skin, soak the wound area with a 1:10 dilution of fresh household bleach for 10 minutes. Rinse with water to remove residual bleach. (Remove contaminated clothing and disinfect with a 1:10 dilution of fresh household bleach.) Obtain medical attention. Ingestion If ingested, wash out mouth with water. Call a physician. Section 5 Fire Fighting Measures Flash Point Not applicable Flammable Limits Not applicable Autoignition Temp. Not applicable Extinguishing Media Use extinguishing media suitable for surrounding fire. Special Fire and Explosion Hazards No special hazards determined. Hazardous Combustion Products Due to the composition and volume of this product, combustion products generated from it are not expected to present a significant hazard. Protective Equipment for Firefighters Selfcontained breathing apparatus is recommended for firefighters. Section 6 Accidential Release Measures Personal Precautions Use universal precautions during clean up procedures. Spill and Leak Procedures As a precautionary measure, treat spilled material with a 1:10 bleach/water solution. Absorb liquid and place in container suitable for disposal. Avoid generation of aerosols during clean up. Comply with applicable waste disposal regulations. Environmental Precautions Contain spill to prevent migration. Section 7 Handling and Storage Handling Precautions This product should be handled as though capable of transmitting infectious diseases. Universal precautions should be followed when using this product. Recommended Storage Conditions Keep away from incompatible material. To maintain efficacy, store according to the instructions in the product labeling. Section 8 Exposure Controls and Personal Protection Exposure Limits US OSHA: None established ACGIH: None established DFG MAK: None established FREE T3 CALIBRATORS S0, S1, S2, S3, S4, S5 MSDS # 3385575 AA Page 3 of 5 Section 8 Exposure Controls and Personal Protection (Continued) Engineering Controls Use in well ventilated area. Respiratory Protection Under normal conditions, the use of this product should not require respiratory protection. If overexposure should occur and ventilation is not adequate to maintain airborne concentrations at acceptable levels, the use of respiratory protection should be evaluated by a qualified professional. Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact. Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin contact. Section 9 Physical and Chemical Properties Physical State Liquid Color Light yellow Transparency Translucent Odor Musty Odor Threshold Not applicable pH 7.4 Boiling Point Not available Melting Point Not available Specific Gravity 1.025 @20°C Vapor Pressure Not available Vapor Density Not available Evaporation Rate Not available Coefficient of Water/Oil Distribution Not available Percent Volatiles Not available Solubility Water Miscible Organic Not available Section 10 Stability and Reactivity Stability Stable under normal temperatures and pressures. Hazardous Incompatibilities Metals and metallic compounds Strong Oxidizers Perchloric Acid Sodium azide forms explosive compounds with heavy metals. Repeated contact of low concentrations of azide with lead and copper commonly found in plumbing drains may result in the build up of shock sensitive compounds. Hazardous Decomposition Products When stored as labeled, no known hazardous decomposition products are formed during the shelflife of this product. Conditions to Avoid Keep away from incompatible material. FREE T3 CALIBRATORS S0, S1, S2, S3, S4, S5 MSDS # 3385575 AA Page 4 of 5 Section 11 Toxicological Information Toxicity Data for Hazardous Ingredients Not applicable Primary Routes of Exposure Common routes of entry include inhalation, ingestion and eye/skin contact. Specific paths of concern for potentially infectious materials are skin puncture, contact with broken skin, contact with mucous membranes and inhalation of aerosolized material. Potential Effects of Acute Exposure Exposure to ProClin 300 may result is irritation of skin, eyes and mucous membranes. Skin contact may result in possible sensitization. Eye contact may cause clouding of the cornea. Ingestion may cause gastrointestinal irritation; large doses given to animals resulted in collapse and coma. This product contains material of human origin and should be considered as potentially capable of transmitting infectious diseases. Potential Effects of Chronic Exposure Frequent or longterm eye and skin exposure to ProClin 300 may result in conjunctivitis and dermatitis. Symptoms of Overexposure Symptoms may include: coughing, headache, fatigue, nausea, vomiting, dizziness, blurred vision, red and watery eyes, abdominal pain and unconsciousness. Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I. Other Effects None identified. Conditions Aggravated by Exposure None identified. Section 12 Ecological Information Ecotoxicity No information available. Biodegradability No information available. Mobility No information available. Section 13 Disposal Considerations Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance with federal, state and local regulations. If unsure of the applicable requirements, contact the authorities for information. Sodium azide preservative may form explosive compounds in metal drain lines. See NIOSH Bulletin: Explosive Azide Hazard (8/16/76). Section 14 Transport Information Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG. FREE T3 CALIBRATORS S0, S1, S2, S3, S4, S5 MSDS # 3385575 AA Page 5 of 5 Section 15 Regulatory Information US Federal and State Regulations SARA 313 Methanol is subject to reporting requirements of Section 313, Title III of SARA. Sodium Azide is subject to reporting requirements of Section 313, Title III of SARA. CERCLA RG s, 40 CFR 302.4 Methanol is listed. Sodium Azide is listed. California Proposition 65 No ingredients listed Massachusetts MSL Methanol is listed. Sodium Azide is listed. New Jersey Dept. of Health RTK List Methanol is listed. Sodium Azide is listed. Pennsylvania RTK Methanol is listed. Sodium Azide is listed. EU Dangerous Ingredients: EINECS Number Classification Risk and Safety Phrases ProClin* 300: 0 C Corrosive R43 May cause sensitization by skin contact. R34 Causes burns. Canada This product is exempt from WHMIS label and MSDS requirements. PIN: Not applicable Ingredients on Ingredient Disclosure List: Methanol Sodium Azide Ingredients with unknown toxicological properties: None Section 16 Other Information * ProClin is a trademark of the Rohm and Haas Company. For further information, please contact your local Beckman representative. WHILE BECKMAN INSTRUMENTS, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN MAKES NO WARRANTY OR REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS. Printed in U.S.A.