This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the information
contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet must be determined by the user
to be in accordance with appropriate applicable regulations.
For Further Asia Pacific Canada Former Soviet Union Japan Norway Spain USA
Information, +852 2811 8693 1 800 463 5800 +7 (095) 232 0250 81 3 5331 9337 63 89 23 10 935 944 950 USB Corporation
contact your (216) 765-5000
local USB Australia Central and East Europe France Latin America Portugal Sweden If purchased from
authorized +61 2 9894 5188 +43 1 982 3826 0169 18 28 00 +55 11 3667 5700 01 417 70 35 018 164000 Amersham Pharmacia
distributor, Biotech use
Amersham Austria Denmark Germany Middle East and Africa South East Asia Switzerland 1 800 526 3593
Pharmacia 01 576 0616 10 +45 4516 2400 07 61 49 03 0 +30 (1) 96 00 687 60 3 724 2080 01 802 81 50
Biotech
Belgium Finland Italy Netherlands South East Europe UK
0800 73888 358 (9) 512 3940 02 27322 1 0165 580 410 +43 (1) 982 3826 0800 515313
MSDS information may be continued on back of page.
Material Safety Data Sheet
Revision: 08/16/2001
Haza rd inform ation is p rovide d for co mplian ce w ith both the UK Chem icals
(Hazard Inform ation and Pack aging) (CHIP) Re gulations and the US Haz ard
Communication Standard (HCS)
IDENTIFICATION OF THE
SUBSTANCE/PREPARATION
AND COMPANY
PRODUCT NAM E:
Tris-Glycin e-SDS Buffer,
10X Solution (Ultrapure)
PRODUCT COD E:
75895
EEC NUMBER:
None
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Outside USA & Canada 703 527 3887
COMPOSITION/
HAZARDOUS COMPO NENTS HAZARD CAS NO.
%WT
TLV CHIP R & S Phrases
Sodium D odecyl Sulfate
Tris
For the mixture / preparation:
151-21 -3
77-86-1
1%
3%
---
R:22 Harmful if swallowed
R:36/37/38 Irritating to eyes,
respira tory sy stem and sk in
S:24/25 A void contact w ith
skin and eyes
HAZARDS IDENTIFICATION CHIP
Harmful
HCS
Irritant
FIRST-AID MEASURES EYES : Flush w ith water fo r 15 min utes. See k med ical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and wash
before reuse. Seek medical attention if irritation persists.
INHALA TION: Re move the victim from ex posure and move to fres h air. If breathing is difficult, give oxygen. If
not breath ing, give artificial re spiration. K eep victim quiet and warm . Seek im mediate medica l attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mo uth to an uncon scious pe rson.
FIRE-FIGHTING INFORMATION Use m edia su itable to exting uish th e supp orting o r surrou nding fire. We ar NIO SH (o r equiv alent) a pprov ed self
conta ined br eathin g app aratus . For sm all fires on ly: use c arbon dioxide , dry po wde r or foam . Und er certa in
conditions of combustion, may emit toxic fumes of sulfur dioxide, carbon monoxide and carbon dioxide.
Flash Point = 212°F (Closed Cup) for SDS.
ACCIDENTAL RELEASE MEAS URES Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH -approved res pirator. Collect in a man ner that does no t create dust and place in a suitable wa ste
container. Avoid contact of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH -approved res pirator. Avoid con tact of material with sk in or eyes. Use a dequate ve ntilation. Store
ambient away from oxidizing agents and mineral acids. Avoid heat or acidic conditions.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection.
Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of
material with skin or e yes. Mech anical ventilation or local exha ust as needed to control expos ure to dust,
vapors or mists. Access to a safety shower and eye-wash.
PHYSICAL AN D CHEMICA L
PROPERTIES
App earan ce: SD S in so lution (M ay be precip itated) Bo iling Poin t: No d ata av ailable
Vapo r Press ure: N o data availab le Vapor De nsity: N o data availab le
Solubil i ty (Water): Soluble Speci f ic Gravity: ~0.35 g/cm3 (for SDS)
Perce nt Vo latile: No data av ailable Evapo ration R ate: No data av ailable
Chemical formula: C12-H26-O4-S A Na
STABILITY AND REACTIVITY Product is stable. Avoid heat or acidic conditions. Incompatible with oxidizing agents and mineral acids. When
heated to decomposition may emit toxic fumes of sulfur dioxide, carbon monoxide and carbon dioxide.
Hazardou s polymerization will not occur.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOS URE:
EYES: Contact may cause severe irritation and possible temporary eye injury.
SKIN: C ontact m ay caus e irritation and /or allergic reac tions. Chro nic conta ct expo sure m ay lead to drying,
cracking, redness and dermatitis. May be harmful if absorbed through the skin.
INHA LATIO N: Ma y cause irritation to the u pper resp iratory tract. M ay be ha rmful if inhale d. Strong sensitizer.
Symp toms o f exposu re may include bu rning sen sation, cou ghing, w heezing , laryngitis, sho rtness of b reath,
headache, nausea and vomiting. May cause allergic respiratory reaction. Pulmonary sensitization resulting in
hyperac tive airwa y dysfu nction an d pulm onary a llergy acco mpan ied by fatigu e, malaise , and ach ing.
Significant symp toms of exp osure can pe rsist for more than tw o years and c an be activated by a variety of
nonspe cific environ menta l stimuli such as autom obile exha ust, perfum es and p assive sm oking.
INGESTION: Chronic ingestion or excessive dosage may cause irritation of the mouth, throat, esophagus and
gastrointestinal tract. May be harmful if ingested.
Target Organ(s): Lungs.
ADDITIONAL INFORMATION:
Reproductive effects, irritation, mutation and toxicity data listed in RTECS under WT1050000.
Oral Rat LD50 = 1288 m g/kg (London, UK - 1967). Inhalation Rat LC50 = >390 0 mg/m3/1H. Toxic effects
may included ataxia and gastrointestinal hypermotility, diarrhea.
Reprod uctive: Effe cts on em bryo or fe tus include d fetotox icity (excep t death, e.g . stunted fe tus)(197 6).
Definition(s): RTECS = Registry of Toxic Effects of Chemical Substances.
ECOLOGICAL INFORMATION No information available.
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: No applicable information.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 - No applicable information.
SARA 313 - No applicable information.
EPA TSCA Section 8(b) - Chemical Inventory.
Section 8(d) - unpublished health/safety studies.
Section 8(e) - Risk Notification, 8EHQ-0892-8800.
Exposure Limits - Not established.
California Proposition 65 - No applicable information.