International Chemical Safety Cards (WHO/IPCS/ILO)International Chemical 
      Safety Cards 
            NICOTINE ICSC: 0519 
            NICOTINE
            (S)-3-(1-Methylpyrrolidin-2-yl)pyridine
            3-(1-Methyl-2-pyrrolidinyl)pyridine
            b-Pyridyl-a-N-methylpyrrolidine
            1-Methyl-2-(3-pyridyl)pyrrolidine
            C10H14N2
            Molecular mass: 162.2

            CAS # 54-11-5 
            RTECS # QS5250000
            ICSC # 0519
            UN # 1654
            EC # 614-001-00-4


            TYPES OF
            HAZARD/
            EXPOSURE ACUTE HAZARDS/
            SYMPTOMS PREVENTION FIRST AID/
            FIRE FIGHTING 
            FIRE Combustible. Gives off irritating or toxic fumes (or gases) in 
            a fire. 
            NO open flames. 
            Powder, alcohol-resistant foam, water spray, carbon dioxide. 

            EXPLOSION Above 95°C explosive vapour/air mixtures may be formed. 
            Above 95°C use a closed system, ventilation. 



            EXPOSURE 
            PREVENT GENERATION OF MISTS! AVOID EXPOSURE OF (PREGNANT) WOMEN! 
            IN ALL CASES CONSULT A DOCTOR! 

            INHALATION 
            Burning sensation. Nausea. Vomiting. Convulsions. Abdominal pain. 
            Diarrhoea. Headache. Sweating. Weakness. Dizziness. Confusion. 
            Ventilation, local exhaust, or breathing protection. 
            Fresh air, rest. Refer for medical attention. 

            SKIN 
            MAY BE ABSORBED! Redness. Burning sensation (see Inhalation). 
            Protective gloves. Protective clothing. 
            Remove contaminated clothes. Rinse and then wash skin with water and 
            soap. Refer for medical attention. 

            EYES 
            Pain. Redness. 
            Safety goggles, face shield, or eye protection in combination with 
            breathing protection. 
            First rinse with plenty of water for several minutes (remove contact 
            lenses if easily possible), then take to a doctor. 

            INGESTION 
            (see Inhalation). 
            Do not eat, drink, or smoke during work. Wash hands before eating. 
            Give a slurry of activated charcoal in water to drink. Induce 
            vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. 

            SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING 
            Collect leaking liquid in sealable containers. Absorb remaining 
            liquid in sand or inert absorbent and remove to safe place. Do NOT 
            wash away into sewer (extra personal protection: complete protective 
            clothing including self-contained breathing apparatus). 
            Provision to contain effluent from fire extinguishing. Separated 
            from strong oxidants, food and feedstuffs. Dry. Ventilation along 
            the floor. 
            Do not transport with food and feedstuffs. 
            T+ symbol
            R: 25-27
            S: (1/2-)36/37-45
            UN Hazard Class: 6.1
            UN Packing Group: II

            SEE IMPORTANT INFORMATION ON BACK 
                  ICSC: 0519 Prepared in the context of cooperation between the 
                  International Programme on Chemical Safety & the Commission of 
                  the European Communities © IPCS CEC 1993 


      International Chemical Safety Cards 
            NICOTINE ICSC: 0519 

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                  PHYSICAL STATE; APPEARANCE:
                  OILY, COLOURLESS HYGROSCOPIC LIQUID , WITH CHARACTERISTIC 
                  ODOUR. TURNS BROWN ON EXPOSURE TO AIR. 

                  PHYSICAL DANGERS:


                  CHEMICAL DANGERS:
                  The substance decomposes on heating producing toxic fumes 
                  including nitrogen oxides and carbon monoxide. Reacts 
                  violently with strong oxidants. 

                  OCCUPATIONAL EXPOSURE LIMITS (OELs):
                  TLV: 0.5 mg/m3 (as TWA) (skin) (ACGIH 1996). 
                  MAK: 0.07 ppm; 0.5 mg/m3; H (1996). 


                  ROUTES OF EXPOSURE:
                  The substance can be absorbed into the body by inhalation and 
                  through the skin, and by ingestion. 

                  INHALATION RISK:
                  A harmful contamination of the air can be reached rather 
                  quickly on evaporation of this substance at 20°C. 

                  EFFECTS OF SHORT-TERM EXPOSURE:
                  The substance irritates the eyes and the skin. The substance 
                  may cause effects on the cardiovascular system and central 
                  nervous system , resulting in convulsions and respiratory 
                  failure. Exposure far above the OEL may result in death. The 
                  effects may be delayed. Medical observation is indicated. 

                  EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
                  Animal tests show that this substance possibly causes toxic 
                  effects upon human reproduction. 

            PHYSICAL
            PROPERTIES
                  Boiling point (decomposes): 247°C
                  Melting point: -80°C
                  Relative density (water = 1): 1.01
                  Solubility in water: miscible 
                  Vapour pressure, kPa at 20°C: 0.006
                  Relative vapour density (air = 1): 5.6
                  Relative density of the vapour/air-mixture at 20°C (air = 1): 
                  1.00
                  Flash point: 95°C c.c. 
                  Auto-ignition temperature: 240°C
                  Explosive limits, vol% in air: 0.7-4
                  Octanol/water partition coefficient as log Pow: 1.2


            ENVIRONMENTAL
            DATA
            The substance is very toxic to aquatic organisms. Avoid release to 
            the environment in circumstances different to normal use. 

            N O T E S 
            Destruxol, XL All Insecticide are trade names. Transport 
                  Emergency Card: TEC (R)-61G68 
                  NFPA Code: H4; F1; R0; 


            ADDITIONAL INFORMATION 



                  ICSC: 0519 NICOTINE 
                  © IPCS, CEC, 1993 


            IMPORTANT LEGAL NOTICE: Neither the CEC or the IPCS nor any person 
            acting on behalf of the CEC or the IPCS is responsible for the use 
            which might be made of this information. This card contains the 
            collective views of the IPCS Peer Review Committee and may not 
            reflect in all cases all the detailed requirements included in 
            national legislation on the subject. The user should verify 
            compliance of the cards with the relevant legislation in the country 
            of use.